[4T15L-07(3P1237)] Regulation of an Aβ-degrading enzyme activity by genes on chromosome 21

〇Masashi Asai^1,2, Takashi Kawakubo¹, Ryotaro Mori¹, Aimi Kinjo², Shoko Kimura², Shifu Takashima², Keiro Shirotani^1,2, Nobuhisa Iwata^1,2 (1.Dept. of Genome-based Drug Discov., Grad. Sch. of Biomed. Sci., Nagasaki Univ., 2.Dept. of Genome-based Drug Discov., Sch. of Pharm. Sci., Nagasaki Univ.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:45 PM - 12:55 PM

[4T15L-08(3P1238)] UBE3A regulates global protein turnover by negatively controlling the ubiquitin-proteasome pathway

〇Hiroshi Kokubu¹, Janghoo Lim¹ (1.Dept. of Genetics, Yale University School of medicine)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:55 PM - 1:05 PM

[4T15L-09(3P1275)] The role of ASK3 in acetaminophen-induced liver injury

〇Toshiya Machida¹, Isao Naguro¹, Hidenori Ichijo¹ (1.Cell Signaling, Grad. Sch. Pharm. Sci., Univ. Tokyo)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:05 PM - 1:15 PM

[4T15L-10(3P1276)] A Study of Cigarette Smoke-Induced COPD in C57BL/6 Mice: The changes in lung epigenome and proteome after smoking cessation or switching to aerosol from a prototypic modified risk tobacco product

〇Nicolas Sierro¹, Thomas Schneider¹, Marja Talikka¹, Sophie Dijon¹, Ashraf Elamin¹, Blaine Phillips², Emilija Veljkovic¹, Bjoern Titz¹, Florian Martin¹, Nikolai V. Ivanov¹, Julia Hoeng¹, Manuel C. Peitsch¹ (1.Philip Morris International, Research & Development, Neuchatel, Switzerland., 2.Philip Morris International, Research & Development, Singapore.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:15 PM - 1:25 PM

[4T15L-11(3P1277)] Dramatic change in oligosaccharides on serum fucosylated haptoglobin is a possible glyco-biomarker for chronic pancreatitis and pancreatic ductal adenocarcinoma

〇Tomohiro Maekawa¹, Makiko Ueda¹, Yoshihiro Kamada¹, Akiko Yamamoto¹, Hironobu Fujii¹, Tomoaki Sobajima¹, Kimihiro Nishino¹, Shinji Takamatsu¹, Eiji Miyoshi¹ (1.Dept. of Mol. Biochem. & Clin. Invest., Osaka Univ. Grad. Sch. of Med.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:25 PM - 1:35 PM

[4T15L-12(3P1278)] Dual-vector suicide gene therapy using retroviral replicating vectors derived from amphotropic murine leukemia virus and gibbon ape leukemia virus

〇Shuji Kubio¹, Noriyuki Kasahara² (1.Dept. Genetics, Hyogo College Med., 2.Dept. Cell Biol. & Path., Univ. Miami)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:35 PM - 1:45 PM

[4T16L-01(3P0139)] Possible regulatory roles of heparin sulfate on differentiation control of keratinocytes by extracellular syntaxins

〇Nanako Kadono¹, Tomoatsu Horigome¹, Ayumi Nakashima², Tomomi Hasegawa², Hiroko Yano², Yohei Hirai¹ (1.Dep. Bioscience, Grad. Sch. Sci. and Tec., Kwansei Gakuin Univ., 2.Kobayashi Pharmaceutical Co., Ltd.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 11:45 AM - 11:55 AM

[4T16L-02(3P0140)] Epidermis-specific mesotrypsin regulates the process of corneocyte desquamation-The hidden mechanism of desquamation-

〇Masashi Miyai¹, Michio Shibata¹, Haruyo Yamanishi¹, Akira Motoyama¹, Yuuko Matsumoto¹, Mami Tanaka-Yamamoto^1,2, Ryoji Tsuboi², Toshihiko Hibino¹ (1.Shiseido Research Center, 2.Department of Dermatology, Tokyo Medical University)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 11:55 AM - 12:05 PM

[4T16L-03(3P0141)] The role of LRP1-mediated endocytosis of metalloproteinases in extracellular matrix turnover

〇Kazuhiro Yamamoto¹, Hideaki Nagase¹ (1.Kennedy Inst. of Rheumatology, Univ. of Oxford)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:05 PM - 12:15 PM

[4T16L-04(3P0142)] Meso-scale intracellular molecular-patterning in bacteria: cell division septum positioning by the Min system

〇Kiyoshi Mizuuchi¹, Anthony G. Vecchiarelli¹, Min Li¹, Michiyo Mizuuchi¹, Ling Chin Hwang¹, Yeonee Seol¹, Keir C. Neuman¹ (1.National Institutes of Health)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:15 PM - 12:25 PM