[1P1222] Functional analysis of miR-17-92 cluster in chronic pain and neurite outgrowth following nerve injury

〇Atsushi Sakai¹, Noriko Miyake², Motoyo Maruyama^1,3, Koichi Miyake², Takashi Shimada², Takashi Okada², Hidenori Suzuki¹ (1.Dept. of Pharmacol., Nippon Med. Sch., 2.Dept. of Biochem. Mol. Biol., Nippon Med. Sch., 3.Div. of Lab. Anim. Sci., Nippon Med. Sch.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1223] Development of novel Drosophila model for Amyotrophic Lateral Screlosis (ALS) and Charcot-Marie-Tooth disease (CMT) by knockdown of the dFIG4 gene and identification of its genetic interactants

〇Akane Kyotami^1,3, Yumiko Azuma², Itaru Yamamoto^1,3, Hideki Yoshida^1,3, Ikuko Mizuta², Toshiki Mizuno², Masanori Nakagawa⁵, Takahiko Tokuda^2,4, Masamitsu Yamaguchi^1,3 (1.Dept. of Appl. Bio., Grad. Sch. of Sci. Technol., Kyoto Inst. of Technol, 2.Dep. of Neuro., Grad. Sch. of Med. Sci., Kyoto Prefec. Uni.of Med, 3.Insect Biomed. Res. Ctr., Kyoto Inst. of Technol, 4.Dep. of Molecular Pathobiology of Brain Diseases, Grad. Sch. of Med. Sci., Kyoto Prefec. Uni.of Med, 5.North Medical Center, Kyoto Prefec. Uni.of Med)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1224] Molecular mechanism for abnormal prion protein accumulation during prion infection

〇Keiji Uchiyama¹, Mitsuru Tomita¹, Suehiro Sakaguchi¹ (1.Inst. for Enz. Res., Tokushima Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1225] Mechanism of glutathione reduction in the 2nd generation mouse model of Alzheimer's disease

〇Shoko Hashimoto¹, Takashi Saito¹, Takaomi C. Saido¹ (1.RIKEN BSI)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1226] Genetic screen for common pathway(s) in which ALS-causing genes involve by using Drosophila model

〇Aya Nakamura¹, Masamitsu Yamaguchi^1,3, Itaru Yamamoto¹, Akane Kyotami¹, Hideki Yoshida¹, Yumiko Azuma², Ikuko Mizuta², Toshiki Mizuno², Masanori Nakagawa⁵, Takahiko Tokuda^2,4 (1.Dep. of Neuro., Grad.Sch. of Med.Sci.,Kyoto Prefec.Uni.of Med, 2.Dep.of Neuro.,Grad.Sch.of Med.Sci., Kyoto Prefec.Uni.of Med, 3.Insect Biomed. Res.Ctr., Kyoto Inst. of Technol, 4.Dep.of Molecular Parthology of Brain Diseases, Grad.Sch.of Med.Sci.,Kyoto Prefec.Uni.of Med, 5.North Medical Center, Kyoto Prefec. Uni.of Med)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1227] Inhibitory effect of apomorphine on LPS-induced IL-23 expression in HAPI cells

〇Hirokazu Hara¹, Dai Kimoto¹, Tetsuro Kamiya¹, Tetsuo Adachi¹ (1.Gifu Pharma. Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1228] Pathogenic mutations in ALS2 alter the oligomeric state of the ALS2 complex and its subcellular localization

〇Kai Sato¹, Yui Hiratsuka¹, Asako Otomo¹, Shinji Hadano¹ (1.Dept.Mol Life Sci,Tokai Univ Sch Med)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1229] The mechanism of FUS R495X aggregation

〇Daiki Kawahara¹, Tadashi Nakaya¹, Toshiharu Suzuki¹ (1.Lab. of NeuroSci.,Grad.Sch.of Pharm.,Univ of Hokkaido)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1230] NADH diphosphatase activity promotes injury-induced axonal degeneration

〇Shinji Tokunaga¹, Toshiyuki Araki¹ (1.Dept. of PNS Res., Natl. Inst. of Neurosci., NCNP)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P1231] Comprehensive profiles of molecules with altered expression in the brain of Ts1Cje, a mouse model of Down syndrome, by omics analyses

〇Ryohei Shimizu¹, Eri Kawashita¹, Ryosuke Takekoshi¹, Haruhiko Sago², Kazuhiro Yamakawa³, Satoshi Akiba¹, Keiichi Ishihara¹ (1.Dept. of Pathol. Biochem., Kyoto Phaem. Univ, 2.Div. of Fetal Med., Natl. Cent. for Child Health & Dev., 3.Lab. for Neurogenetics, BSI, RIKEN)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM