[1W4-p-6] Local production of S-adenosylmethionine for local consumption to promote and to regulate methylation of chromatin and beyond

〇Kazuhiko Igarashi¹, Masayuki Ebina¹, Hiroki Shima¹, Yasutake Katoh^1,2 (1.Dept. Biochem., Grad. Sch. Med., Tohoku Univ., 2.Tohoku Med. Megabank, Tohoku Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:07 PM - 3:22 PM

[1W4-p-7] Mediator complex cooperatively regulates transcription of retinoic acid-target genes with Polycomb repressive complex PRC2 during neuronal differentiation

〇Yoshiaki Ohkuma^1,2, Satoshi Iida¹, Taiki Tsutsui^1,3, Yutaka Hirose¹, Rikiya Fukasawa¹ (1.Lab. Gene Reg., Grad. Sch. Med. & Pharm. Sci., Univ. Toyama, 2.Dept. Biochem., Nagasaki Univ. Sch. of Med., 3.Dept. Cell. & Mol. Med., UCSD Sch. Me.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:22 PM - 3:37 PM

[1W4-p-8] Role of Human Mediator Subunit Med26 in Transcription Elongation

〇Hidehisa Takahashi¹, Joan W. Conaway², Ronald C. Conaway², Shigetsugu Hatakeyama¹ (1.Dept. of Biochem. Hokkaido Univ. Grad. Sch. of Med., 2.Stowers Institute for Medical Research)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:37 PM - 3:52 PM

[1W4-p-9] Noncanonical histone-containing particles in dynamic chromatin

Jia Fei¹, Mai T. Khuong¹, Sharon E. Torigoe¹, Christopher R. Brown², Hinrich Boeger², Haruhiko Ishii³, Bing Ren³, 〇James T. Kadonaga¹ (1.UCSD, 2.UC Santa Cruz, 3.Ludwig Institute, UCSD)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:52 PM - 4:27 PM

[Conclusion] Conclusion

〇Yoshiaki Ohkuma¹ (1.Nagasaki University)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:27 PM - 4:30 PM

[1W5-p-1] Significance of Rare Disease Research

〇Kosuke Izumi¹, Katsuhiko Shirahige¹ (1.IMCB, Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 2:00 PM - 2:20 PM

[1W5-p-2] Abnormal Endosome System Equilibrium in MIRAGE Syndrome Caused by Activating SAMD9 Mutations

〇Satoshi Narumi¹, Naoko Amano¹, Tomohiro Ishii¹, Noriyuki Katsumata², Ryuji Fukuzawa³, Shinsuke Shibata⁴, Hideyuki Okano⁴, Atsushi Shimizu⁵, Noriko Miyake⁶, Naomichi Matsumoto⁶, Tomonobu Hasegawa¹ (1.Pediatrics, Keio Univ. Sch. of Med., 2.Mol. Endocrinol., Natl. Res. Institute for Child Health & Dev., 3.Pathology, Tokyo Met. Children Med. Center, 4.Physiology, Keio Univ. Sch. of Med., 5.Tohoku Med. Megabank Organization, 6.Hum. Genet., Yokohama City Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 2:20 PM - 2:45 PM

[1W5-p-3] Dominant mutations in ORAI1 cause tubular aggregate myopathy

〇Ichizo Nishino¹ (1.Dept. of Neuromucul. Res., NIN, NCNP)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 2:45 PM - 3:10 PM

[1W5-p-4] Identification of novel genes and mouse modeling in RASopathies

〇Yoko Aoki¹, Shin-ichi Inoue¹, Tetsuya Niihori¹, Yoichi Matsubara² (1.Dept.Med.Genet., Tohoku.Univ.Sch.Med, 2.Natl. Res.Inst.Child Health.Develop.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:10 PM - 3:35 PM

[1W5-p-5] From Cohesinopathies to Transcriptomopathies: Insights from Cornelia de Lange Syndrome and Related Diagnoses

〇Ian D. Krantz¹ (1.The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 3:35 PM - 4:05 PM