[2P1153(2T特p-04)] Suppression of immune responses by non-immunogenic oligodeoxynucleotides with high-affinity for HMGB proteins

〇Kosuke Matsuki¹, Hideyuki Yanai¹, Tadatsugu Taniguchi¹ (1.Dept. of Mol. Immunol., IIS., The Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1154(2T特p-05)] Mitochondrial damage induces antiviral innate immune response

〇Tatsuya Saitoh^1,2,3, Tatsuya Kozaki^1,2,3, Shizuo Akira^2,3 (1.Div of Mol Genetics, IER, Tokushima Univ, 2.Lab of Host defense, IFReC, Osaka Univ, 3.Dep of Host defense, RIMD, Osaka Univ)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1155(2T特p-06)] Prostaglandin E2 inhibits neutrophil extracellular traps formation through production of cyclic AMP

〇Tomohiro Kimura¹, Kyosuke Shishikura¹, Takahiro Horiuchi¹, Natsumi Sakata¹, Duc-Anh Trinh¹, Ryutaro Shirakawa¹, Hisanori Horiuchi¹ (1.Dept. of Mol. Cell. Biol., Inst. of Dev. Aging and Cancer, Univ. of Tohoku)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1156(2T特p-07)] The role of Polyprimidine tract binding protein-1 (PTBP1) in B cell development and function

〇Hiroki Sasanuma¹, Nobuaki Yoshida¹ (1.IMSUT, Univ. of Tkyo)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1157(2T特p-08)] Regulation of IL-7 signaling and immunoglobulin gene recombination by the transcription factor Sip1

〇Tatsunari Hayashi¹, Yukiko Nambu¹, Hiroto Mano¹, Kyoungjin Jang¹, Yujiro Higashi², Verschueren Kristin³, Huylebroeck Danny³, Akira Shimizu¹, Manabu Sugai¹ (1.iACT, Kyoto Univ Hosp., 2.Inst. Dev. Res., Aichi Human Service Ctr., 3.Lab. Mol. Biol., Campus Gasthuisberg K/U. Leuven)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1158(2T特p-09)] Functional defect of regulatory T cells in chronic colitis due to epithelial barrier dysfunctions

〇Takahiro Yamada¹, Yukihiro Furusawa², Yuuki Obata^1,3, Daisuke Takahashi¹, Kouji Hase^1,3 (1.Grad. Sch. of Pharm., Keio Univ., 2.Dept. of Libe. and Sci., Toyama Pref. Univ., 3.Inst. of Med. Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1159(2T特p-10)] Monoclonal intestinal IgAs are poly-reactive but recognize a specific amino acid sequence of protein expressed by multiple bacteria.

〇Fumihito Usui¹, Shinsaku Okai¹, Makoto Hasegawa², Kazuya Yamamoto³, Eri Nishiyama³, Hiroshi Mori³, Takuji Yamada³, Ken Kurokawa⁴, Reiko Shinkura^1,5 (1.Dept. of Immunol.,Nagahama Institute of Bioscience and Technology, 2.Dept. of Protein Function Analysis,Nagahama Institute of Bioscience and Technology, 3.Grad. Sch. of Bioscience and Biotechnology, Tokyo Institute of Technology, 4.Earth-Life Sci., Tokyo Institute of Technology, 5.PRESTO)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1160(2T特p-11)] High-affinity, poly-reactive IgA is required for gut homeostatic maintenance to prevent colitis in mice.

〇Shinsaku Okai¹, Fumihito Usui¹, Makoto Hasegawa¹, Toshinobu Nakamura², Kazuya Yamamoto³, Eri Nishiyama³, Hiroshi Mori³, Takuji Yamada³, Ken Kurokawa⁴, Tamotsu Kato⁵, Eiji Miyauchi⁵, Hiroshi Ohno^5,6,7,8, Reiko Shinkura^1,9 (1.Department of Immunology, Nagahama Institute of Bioscience and Technology, 2.Department of Epigenetics, Nagahama Institute of Bioscience and Technology, 3.Graduate School of Bioscience and Biotechnology,Tokyo Institute of Technology, 4.Earth-Life Science Institute,Tokyo Institute of Technology, 5.RIKEN Center for Integrative Medical Sciences (IMS), 6.Graduate School of Medicine, Chiba University, 7.Graduate School of Medical Life Science, Yokohama City University, 8.AMED-CREST, 9.PRESTO)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1161(2T特p-12)] Analysis of Interleukin-11 producing cells in a colitis-associated cancer model using IL-11 reporter mice

〇Takashi Nishina¹, Yutaka Deguchi¹, Masato Ohtsuka², Eri Nakamura³, Yuko Kojima⁴, Tetsuo Mikami⁵, Norihiro Tada³, Hiroyasu Nakano¹ (1.Dep. of Biochem., Toho Univ. Sch. of Med., 2.Dep. of Mol. Life Sci., Div. of Basic Med. Sci. and Mol. Med., Tokai Univ. Sch. of Med., 3.Lab. of Genome Res., Res. Inst. for Dis. of Old Age, Juntendo Univ. Grad. Sch. of Med., 4.Lab. of Biomed. Imaging Research, Biomed. Res. Center, Juntendo Univ. Grad. Sch. of Med.,, 5.Dep. of Patho., Toho Univ. Sch. of Med.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P1162(2T特p-13)] GADD34 promotes inflammation and colon carcinogenesis in murine colitis associated-cancer model

〇Yuriko Tanaka¹, Sachiko Ito¹, Ken-ichi Isobe^1,2 (1.Dept. of Immunol., Grad. Sch. of Med., Nagoya Univ., 2.Dept. of Food Sci. and Nutr., Nagoya Wumen's Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM