[2P0187(2T21-10)] IRS-1 is a novel feedback regulator of IGF-I receptor endocytosis via its association with AP-2 clathrin adaptor complex.

〇Yosuke Yoneyama¹, Kazuhiro Chida¹, Fumihiko Hakuno¹, Shin-Ichiro Takahashi¹ (1.Dept. of Anim. Res. Sci., Grad. Sch. of Agri. Life Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0188(2T21-11)] Roles of the Dok adaptor proteins in osteoclast differentiation.

〇Shuhei Kajikawa¹, Yuu Taguchi², Tadayoshi Hayata³, Yoichi Ezura⁴, Sumimasa Arimura¹, Jun-ichiro Inoue², Masaki Noda⁴, Yuji Yamanashi¹ (1.Div. of Genet., Inst. of Med. Sci., Univ. of Tokyo, 2.Div. of Cell. and Mol. Biol., Inst. of Med. Sci., Univ. of Tokyo, 3.Dep. of Biol. Sig. and Reg., Fac. of Med., Univ. of Tsukuba, 4.Dept. of Mol. Pharmacol., MRI, TMDU)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0189(2T21-12)] Inhibition of PRMT5-Gli1 pathway suppress tumor recurrence and anticancer drug resistant tumor formation in non-small cell lung cancer

〇Yoshibori Abe¹, Susumu Takeuchi², Nobuyuki Tanaka¹ (1.Dept. of Mol. Oncl., Inst. for Adv. Med. Sci., Nippon Med. Sch., 2.Dept. of Plum. Med. and Oncl., Grad. Sch. of Med., Nippon Med. Sch.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0190(2T21-13)] Functional analysis of TRB1 in tumorigenesis and TRB1 as a potential target for cancer therapy

〇Chiaki Suzuki¹, Chiharu Miyajima², Yasumichi Inoue¹, Hiromi Iwanaka¹, Yuka Itoh¹, Hidetoshi Hayashi¹ (1.Dept. of Cell Signal., Grad. Sch. of Pharm. Sci., Ngoya City Univ., 2.Dept. of Mol. Biol., Hamamatsu Univ. Sch. of Med.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0191] Requirement of Loxl2 for TGF-β-induced epithelial-mesenchymal transition

〇Takahito Tanaka¹, Arisa Nishio¹, Yasumichi Inoue¹, Chihiro Sumita¹, Yuka Itoh¹, Hidetoshi Hayashi¹ (1.Dept. of Cell Signal., Grad. Sch. of Pharm. Sci., Nagoya City Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0192] Regulation of TRB1 gene expression by TGF-β and functional characterization of TRB1 in TGF-β signaling

Miki Sawanaka¹, Eriko Mizukawa¹, 〇Yuka Itoh¹, Yasumichi Inoue¹, Hidetoshi Hayashi¹ (1.Dept. of Cell Signal., Grad. Sch. of Pharm. Sci., Nagoya City Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0193(2T21-14)] Cytoplasmic RelA/TAD regulates IKK activation

〇Yoshihiro Tsuchiya¹, Toru Higuchi¹, Yasuka Matsunaga¹, Ena Takahashi¹, Yusuke Nakatsu¹, Tomoichiro Asano¹, Hideaki Kamata¹ (1.Dep. of Med., Gra. Sch. of Biomed. Health Sci., Hiroshima Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0194(2T21-15)] NPM1 enhances inflammatory genes mediated by NF-kB

〇Jianhuang Lin¹, Mitsuru Okuwaki², Mitsuyasu Kato³, Kyosuke Nagata⁴ (1.Human Biology Program, Univ. of Tsukuba, 2.Dept. of Infection Biol., Univ. of Tsukuba, 3.Dept. of Experimental Pathology, Univ. of Tsukuba, 4.Univ. of Tsukuba)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0195(2T21p-01)] Possible roles of MKK7 in remodeling of the liver following injury

〇Takako Ooshio¹, Masahiro Yamamoto¹, Kiyonaga Fujii¹, Xi Chen¹, Bing Xin¹, Yoko Okada¹, Yuji Nishikawa¹ (1.Div. of Tumor Pathol., Dept. Pathol., Asahikawa Med. Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0196(2T21p-02)] Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling

〇Yuki Shindo^1,2, Kazunari Iwamoto², Kazunari Mouri³, Kayo Hibino^2,3, Masaru Tomita⁴, Hidetaka Kosako⁵, Yasushi Sako³, Koichi Takahashi^2,4 (1.Front. Biosci., Osaka Univ., 2.QBiC, RIKEN, 3.Cell. Inform. Lab., RIKEN, 4.Inst. Adv. Biosci., Keio Univ., 5.Div. Cell Signal., Tokushima Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM