[2P-173（3T09a-01）] Differential digitonin-mediated release of Bcnt/Cfdp1, a chromatin remodeler of intrinsically disordered protein, from the cytoplasm

^〇Shintaro Iwashita¹, Takehiro Suzuki², Takeshi Yasuda³, Koichi Nishimura⁴, Yoshito Kakihara⁵, Yoshimitsu Kiriyama¹, Yoshiharu Ohoka¹, Kentaro Nakashima⁶ (1.Kagawa Sch. of Pharma. Sci. Tokushima Bunri Univ., 2.Biomol. Characterization Unit, CSRS, Riken, 3.iQLS, QST, 4.Grad. Sch. of Bio. Sci., Tokushima Univ. , 5. Niigata Univ. Grad. Sch. Med. Dent. Sci., 6.Inst. of Neurosci., Tokushima Bunri Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-174] Phenylarsine oxide stimulates STING-mediated innate immune activity

^〇Kentaro Matsumoto¹, Shenwei Ni², Kojiro Mukai¹, Yoshiro Saitoh³, Takashi Toyama³, Naoshi Dohmae⁴, Takehiro Suzuki⁴, Tomohiko Taguchi¹ (1.Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, 2.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, 3.Laboratory of Molecular Biology and Metabolism, Graduate School of Pharmaceutical Sciences, Tohoku University, 4.Biomolecular Characterization Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-175（2T17m-06）] Ferritin phase separation driven by NCOA4 promotes ferritin delivery to lysosomes via two pathways, macro-autophagy and endosomal micro-autophagy

^〇Hayashi Yamamoto¹, Tomoko Ohshima¹, Yuriko Sakamaki², Chieko Saito¹, Noboru Mizushima¹ (1.Graduate School and Faculty of Medicine, The University of Tokyo, 2.Research Core, Tokyo Medical and Dental University)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-176（1T17m-08）] Understanding the role of ATG16L1 isoforms in the central nervous system

^〇Kazuya Murata¹, Natsuki Mikami², Yoko Daitoku¹, Misuzu Hashimoto³, Seiya Mizuno¹, Fumihiro Sugiyama¹ (1.Faculty of Medicine, University of Tsukuba, 2.Ph.D. Program in Human Biology, University of Tsukuba, 3.Graduate School of Natural Science and Technology, Gifu University)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-177（2T17m-02）] Analysis of endoplasmic reticulum tethering factors required for selective autophagy

^〇Haruki Tanabe¹, Momoko Higashi¹, Takayuki Shima², Hidetaka Kosako³, Akiko Kuma², Tamotsu Yoshimori^1,2 (1.Osaka University Graduate school of Frontier Biosciences Laboratory of Intracellular Membrane dynamics, 2.Osaka University Graduate school of Medicine , 3.Institute of Advanced Medical Sciences)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-178（1T17m-01）] Selective increment of phosphatidylserine in the autophagic body membrane in the yeast vacuole

^〇Yuki Yamakuchi¹, Akikazu Fujita¹, Shiomi Koudatsu¹, Yuna Kurokawa¹, Kayoko Fukuda¹, Sayuri Kuriyama¹, Tatsunori Masatani² (1.Kagoshima university, 2.Gifu university)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-179（1T17m-04）] Establishment of a novel purification method for p62 droplets and comprehensive search for ubiquitinated proteins in p62 droplets

^〇Shuhei Takada¹, Hideaki Morishita¹, Masaaki Komatsu¹ (Dept. of Physiology, Juntendo Univ. Grad. School of Med.)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-180] Assessment for autolysosome formation using abemaciclib or vacuolin-1 induced vacuole formation

^〇Yoshinori Tanaka¹, Hirotsugu Hino², Kosuke Takeya¹, Masumi Eto¹ (1.Biochem. Unit, Fac. of Veterinary Med., Okayama Univ. of Sci., 2.Div. of Anat. Sci., Dept. of Funct. Morpho., Nihon Univ. Sch. of Med.)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-181（3T17m-04）] Development of novel autophagy inhibitors targeting autophagosome membrane formation

^〇Yudai Kudo¹, Mei Fujita¹, Yuta Yoshino¹, Yuji Kamatari², Yoshimasa Tanaka³, Takeshi Ishikawa⁴, Naohiro Fujimoto⁵, Takuya Okada⁶, Naoki Toyooka⁶, Satoshi Endo¹, Akira Ikari¹ (1.Lab Biochem, Gifu Pharm Univ, 2.Life Science Reserch Center, Gifu Univ, 3.Nagasaki Univ Center for Medical Inovation, 4.Department of Chemistry and Biotechnology, Kagoshima Univ, 5.Department of Urology, U.O.E.H, 6.Faculty of Engineering, Toyama Univ)

The 95th Annual Meeting of the Japanese Biochemical Society

[2P-182] A novel mouse line systemically expressing an autophagic flux reporter revealed autophagy suppression in pathological conditions.

^〇Yuki Kanda¹, Tomoya Eguchi¹, Hideaki Morishita^1,2, Yutaro Hama^1,3, Manabu Abe⁴, Kenji Sakimura⁴, Noboru Mizushima¹ (1.Dept. of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 2.Dept. of Physiology, Juntendo University Graduate School of Medicine, 3.Division of Biological Molecular Mechanisms, Institute for Genetic Medicine, Hokkaido University, 4.Dept. of Cellular Neurobiology, Brain Research Institute, Niigata University)

The 95th Annual Meeting of the Japanese Biochemical Society