[1P-046] LPGAT1/LPLAT7-mediated regulation of acyl chain profiles in murine muscular phospholipids and its function (1)

^〇Shinji Miura¹, Shuhei Umebayashi¹, Tomoki Sato¹, Nanami Senoo¹, Takumi Akahori¹, Hiyori Ichida¹, Noriyuki Miyoshi¹, Takuya Yoshida², Yuki Sugiura³, Naoko Goto-Inoue⁴, Hiroki Kawana⁵, Hideo Shindou^6,7, Takashi Baba⁸, Yuki Maemoto⁸, Yasutomi Kamei⁹, Takao Shimizu¹⁰, Junken Aoki⁵ (1.School of Food and Nutritional Sciences, University of Shizuoka, 2.School of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3.Graduate School of Medicine, Kyoto University, 4.College of Bioresource Sciences, Nihon University, 5.Graduate School of Pharmaceutical Sciences, The University of Tokyo, 6.National Center for Global Health and Medicine, 7.Graduate School of Medicine, The University of Tokyo, 8.School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 9.Graduate School of Environmental and Life Science, Kyoto Prefectural University, 10.Institute of Microbial Chemistry)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-047] Lysophospholipase D activity of intact kidney-derived cell line, NKR52E, possibly due to glycerophosphodisetrease 7

^〇Toshihiko Tsutsumi¹, Kohei Kawabata², Hiroyuki Nishi², Naoshi Yamazaki³, Kenji Tsukigawa⁴, Akira Tokumura^2,3 (1.Graduate School of Clinical Pharmacy, Kyushu University of Health and Welfare, 2.Faculty of Pharmacy, Yasuda Women's University, 3.Faculty of Pharmaceutical Sciences, Tokushima University, 4.Faculty of Pharmaceutical Sciences, Sojo University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-048] Analysis of Deuterium-Labeled Phosphoinositides Using Supercritical Fluid Chromatography-Mass Spectrometry

^〇Tsumugi Iwata¹, Yuki Ishino¹, Shenwei Ni¹, Nozomu Kono^1,2, Junken Aoki ¹ (1.Dept. of Health Chem., Grad. Sch. Of Pharmaceut. Sci, the Univ. of Tokyo, 2.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-049（2T04a-09）] Therapeutic effects of overexpression of lysophosphatidylcholine acyltransferase 4 (LPCAT4)/lysophospholipid acyltransferase 10 (LPLAT10) in the liver on glucose metabolism

^〇Kahori Shimizu¹, Moe Ono¹, Takenari Mikamoto¹, Yuya Urayama¹, Hiroki Nakanishi², Tomoyuki Terada¹, Fuminori Sakurai³, Hiroyuki Mizuguchi^3,4,5,6, Hideo Shindou^7,8, Koji Tomita¹, Toru Nishinaka¹ (1.Faculty of Pharmacy, Osaka Ohtani University, 2.Lipidome Lab Company, Limited., 3.Graduate School of Pharmaceutical Sciences, Osaka University, 4.National Institute of Biomedical Innovation, Health and Nutrition, 5.Global Center for Medical Engineering and Informatics, Osaka University, 6.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), 7.National Center for Global Health and Medicine, 8.Graduate School of Medicine, The University of Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-050（3T04a-02）] Lipid-metabolizing enzyme PNPLA6 maintains retinal homeostasis via choline pathway

^〇Takashi Ono^1,2, Yoshitaka Taketomi¹, Tomoyoshi Soga³, Suzumi Tokuoka⁴, Yoshiya Oda⁴, Makoto Aihara², Makoto Murakami^1,5 (1.CDBIM, UTokyo, 2.Ophthalmol.,UTokyo, 3.IAB, Keio Univ., 4.Lipidomics, UTokyo, 5.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-051] Myristic acid selectively increases beta-tubulin levels in C2C12 myotubes through diacylglycerol kinase delta

^〇Hiromichi Sakai¹, Fumio Sakane² (1.Dpt. of Biosign. and Radioiso. Exp., Interdiscip. Cent. for Sci. Res., Shimane Univ., 2.Dpt. of Chem., Grad. Sch. of Sci., Chiba Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-052（1T04a-09）] Phosphorylation of the splicing regulator SRSF1 by PKA and retinoic acid-induced HL60 cell differentiation

^〇Daisuke Saito¹, Masahiko Imai¹, Shinya Hasegawa¹, Masahiro Yamasaki¹, Noriko Takahashi¹ (Lab. of Physiolog. Chem., Hoshi Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-053] Analysis of levels of bioactive lipids and their metabolic enzymes in social defeat stress-exposed mice.

^〇Katsuya Morito¹, Yuki Nishimura¹, Yusuke Hara¹, Kosuke Hajiri¹, Takeshi Yasukawa², Hirotoshi Morimoto², Kentaro Takayama¹, Yoshinobu Uozumi², Kazuki Nagasawa¹ (1.Kyoto Pharmaceutical University, 2.Ako Kasei Co., Ltd.)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-054（2T04a-07）] The group XIIA secreted phospholipase A₂ regulates Th17 cell differentiation leading to Th17 associated autoimmune diseases

^〇Chika Mochizuki¹, Yoshitaka Taketomi¹, Takahiro Nakajima², Yusuke Endo², Kuniyuki Kano³, Junken Aoki³, Makoto Murakami^1,4 (1.CDBIM, Grad. Sch. Med., UTokyo, 2.Lab. Med. Omics Res., Kazusa DNA Res. Inst, 3.Lab. Health Chem., Grad. Sch. Pharm. Sci., UTokyo, 4.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-055（1T03a-02）] Ablation of cPLA₂ζ impairs cutaneous wound healing

^〇Yuki Nagasaki¹, Yoshitaka Taketomi², Yoshimi Miki², Ken Yasukawa³, Kazuko Saeki³, Takehiko Yokomizo³, Toshiko Yamamoto¹, Makoto Murakami^2,4 (1.Dept. of Nutr. Scie., Okayama Prefectural Univ., 2.CDBIM, Grad. Sch. of Med., UTokyo, 3.Dept. of Biochem., Grad. Sch. of Med., Juntendo Univ., 4.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society