[2T11a-09（1P-268）] Milisecond dynamics of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM

^〇Sajidah Elma Sakinatus¹, Keesiang Lim², Tomoyoshi Yamano³, Takeshi Yoshida^2,3, Akiko Kobayashi⁴, Masaharu Hazawa^2,4, Yuka Inaba⁵, Hiroshi Inoue⁵, Rikinari Hanayama^2,3, Toshio Ando², Richard W. Wong^1,2,4 (1.Division of Nano Life Science in the Graduate School of Frontier Science Initiative, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 2.WPI-Nano Life Science Institute, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 3.Department of Immunology, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan, 4.Cell-Bionomics Research Unit, Institute for Frontier Science Initiative (INFINITI), Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 5.Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative (INFINITI), Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:40 PM - 2:50 PM

[2T12a-01（1P-218）] Protein tyrosine kinase Abl promotes hepatitis C virus particle assembly via interaction with viral substrate activator NS5A

Daisuke Miyamoto^1,2, Kenji Takeuchi^2,3, Kazuyasu Chihara^2,3, Shigeharu Fujieda^1,3, ^〇Kiyonao Sada^2,3 (1.Department of Otorhinolaryngology Head & Neck Surgery, Faculty of Medical Sciences, University of Fukui, 2.2Department of Genome Science and Microbiology, Faculty of Medical Sciences, University of Fukui, 3.Organization for Life Science Advancement Programs, University of Fukui)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:20 PM - 1:30 PM

[2T12a-02（2P-228）] Analysis of function of STAT3 acetylation on carcinogenesis induction by fusion type Tyrosine NPM-ALK

^〇Akira Korai¹, Xin Lin¹, Megumi Tago¹, Kenji Tago² (1.Keio university, 2.Jichi Medical university)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:30 PM - 1:40 PM

[2T12a-03（2P-211）] Identification of novel ubiqutination-related gene for the regulation of tumor suppressor PTEN

^〇Tomohiko Maehama¹, Shintaro Ikesue¹, Miki Nishio¹, Junji Otani¹, Akira Suzuki¹ (Div. Mol. Cell. Biol., Kobe Univ. Grad. Sch. of Med.)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:40 PM - 1:50 PM

[2T12a-04（3P-215）] Analysis of the molecular mechanism of STAT5-independent cell proliferation induced by erythropoietin

^〇Kengo Takeda¹, Kenji Tago², Fumihito Ueda¹, Megumi Tago¹ (1.Division of Hygienic Chemistry, Graduate School of Pharmaceutical Science , Keio University, 2.Division of Structural Biochemistry, Department of Biochemistry, Jichi Medical University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:50 PM - 2:00 PM

[2T12a-05（2P-222）] A novel κB-Ras-binding protein TRB3 exhibits tumor-suppressive activity against oncogenic Ras signaling

^〇Kenji Tago¹, Naoyuki Sugiyama², Satoshi Ohta¹, Chihiro Aoki-Ohmura¹, Jitsuhiro Matsugi¹, Ken Yanagisawa¹, Kaoru Tominaga¹, Hiroshi Itoh³, Megumi Funakoshi-Tago⁴ (1.Division of Structural Biochemistry, Jichi Medical University, 2.Graduate School of Pharmaceutical Sciences, Kyoto University, 3.Department of Cell Biology, Graduate School of Biological Sciences, Nara Institute of Science and Technology, 4.Graduate School of Pharmaceutical Sciences, Keio University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:00 PM - 2:10 PM

[2T12a-06（3P-206）] BAG6 regulates actin stress fiber via controlling RhoA ubiquitination

^〇Maho Miyauchi¹, Hiroyuki Kawahara¹ (Laboratory of Cell Biology and Biochemistry, Department of Biological Sciences, Tokyo Metropolitan University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:10 PM - 2:20 PM

[2T12a-07（3P-209）] Endogenous ligand recognition and structural transition of a human PTH receptor

^〇Kazuhiro Kobayashi¹, Kouki Kawakami², Tsukasa Kusakizako¹, Hirotake Gono¹, Atsuhiro Tomita¹, Kan Kobayashi¹, Wataru Shihoya¹, Keitaro Yamashita^1,3, Tomohiro Nishizawa⁴, Hideaki E. Kato^1,5, Asuka Inoue², Osamu Nureki¹ (1.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2.Graduate School of Pharmaceutical Sciences, Tohoku University, 3.MRC Laboratory of Molecular Biology, , 4.Graduate School of Medical Life Science, Yokohama City University, 5.Komaba Institute for Science, The University of Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:20 PM - 2:30 PM

[2T12a-08（3P-211）] Tumor suppressive activity of RGS16 against oncogenic Ras-provoked signal transduction pathway

^〇Kouki Ohtawa¹, Chihiro Aoki-Ohmura¹, Satoshi Ohta¹, Jitsuhiro Matsugi¹, Megumi Funakoshi-Tago², Kaoru Tominaga¹, Kenji Tago¹ (1.Division of Structural Biochemistry, Department of Biochemistry, School of Medicine, Jichi Medical University, 2.Division of Hygienic Chemistry, Faculty of Pharmacy, Keio University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:30 PM - 2:40 PM

[2T12a-09（2P-226）] FilGAP-mTORC1/2 interaction is involved in glioma progression

^〇Ayumi Nohara¹, Koji Tsutsumi¹, Taiki Tanaka¹, Moe Murano¹, Yasutaka Ohta¹ (Division of Cell Biology, Department of Biosciences, School of Science, Kitasato University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:40 PM - 2:50 PM