[3P-372（1T18e-04）] Microtubule affinity-regulating kinase 4 induces stress granule formation and tau-induced neurodegeneration

^〇Sho Nakajima¹, Aoi Fukuchi¹, Grigorii Sultanakhmetov¹, Akiko Asada^1,2, Taro Saito^1,2, Kanae Ando^1,2 (1.Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 2.Department of Biological Sciences, Faculty of Science, Tokyo Metropolitan University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-373] Erythrocyte-derived extracellular vesicles containing α-synuclein as a potential biomarker of neurodegenerative diseases.

^〇Ryosuke Amagai¹, Ryunosuke Hosoi¹, Sakura Yoshioka¹, Takayuki Kawai², Tomoaki Tanaka³, Ryuji Sakakibara⁴, Ayako Okado-Matsumoto¹ (1.Laboratory of Biochemistry, Department of Biology, Faculty of Science, Toho University., 2.Department of Medical Research, Sakura Medical Center, Toho University., 3.Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University., 4.Division of Neurology, Department of Internal Medicine, Sakura Medical Center, Toho University.)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-374] Effects of direct injection of neurotropin into injured tissues in mouse models for scar formation and associated chronic pain

^〇Xuan Zhou¹, Iida Hiromi ¹, Kimata Koji ¹, Yuqiang Li¹, Akinobu Ota², Takahiro Ushida ¹ (1.Multidisciplinary Pain Center, Aichi Medical University, 2.Department of Biochemistry, Aichi Medical University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-375] Development of unique methodologies to detect Super Sulfide

^〇Miyuki Nara¹, Takashi Toyama¹, Runa Kudo¹, Yoshiro Saito¹ (Division of molecular-biology and metabolism, Department of Pharmaceutical Sciences, Tohoku University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-376] Chemiluminecence probe LISA-103 for the detection of γ-glutamyl cyclotransferase activity

^〇Yukie Nohara¹, Keiko Taniguchi², Hiromi Ii³, Shun Masuda¹, Hiroko Kawakami¹, Masakatsu Matsumoto⁴, Susumu Nakata³, Toshiyuki Sakai², Taku Yoshiya^1,5 (1.Peptide Institute, Inc., 2.Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine, 3.Department of Clinical Oncology, Kyoto Pharmaceutical University, 4.Department of Chemistry, Kanagawa University, 5.Institute for Protein Research, Osaka University )

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-377] Drug discovery using a marine microbial extract library

Jun Takouda¹, Moeka Nakamura¹, Kyoka Koreeda¹, Takuro Sugiyama¹, Kimito Kai¹, Megumi Kuroiwa¹, Shota Jinnai¹, Akane Murasaki¹, Susumu Tanimura¹, Yoshimasa Tanaka², ^〇Kohsuke Takeda^1,2 (1.Cell Regulation, Graduate School of Biomedical Sciences, Nagasaki University, 2.Center for Medical Innovation, Nagasaki University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-378（1T18e-03）] An exploratory study of inhibitors that target YAP-TEAD interaction in the Hippo pathway

^〇Saaya Sekine^1,2, Shohei Takase¹, Kota Noritsugu¹, Rumi Kurokawa², Yasue Ichikawa², Kenji Ogawa^2,3, Ken Matsumoto², Hiroyuki Osada², Minoru Yoshida^2,4, Akihiro Ito^1,2 (1.Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2.RIKEN CSRS, 3.Col. of Biores. Sci., Nihon Univ., 4.Dept. Biotechnol. and CRIIM, Univ. Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-379] Taming AI: Creating a Compound Library with Structural Diversity

^〇Kazutoshi Kiyooka¹, Takuma Shiraki¹ (Graduate School of Biology-Oriented Science and Technology. Kindai University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-380（1T18e-06）] Development of drug repositioning method using kinase inhibitor proteomics

^〇Satomi Ohtsuka¹, Akari Yoshida¹, Naoya Hatano¹, Taisei Okumura², Naoki Sawa², Naoki Kanayama¹, Masaki Magari¹, Teruhiko Ishikawa², Hiroshi Tokumitsu¹ (1.Okayama University Graduate School of Interdisciplinary Science and Engineering in Health Systems, 2.Okayama University Graduate School of Education / Faculty of Education)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-381（1T18e-07）] Development of SLIPT system for chemogenetic control of signaling activity at the plasma membrane in mammalian cells and S. pombe

^〇Akinobu Nakamura^1,2, Sachio Suzuki³, Yuhei Goto^2,4, Shinya Tsukiji³, Kazuhiro Aoki^2,4 (1.Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2.Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 3.Nagoya Institute of Technology, 4.National Institute for Basic Biology, National Institutes of Natural Sciences)

The 95th Annual Meeting of the Japanese Biochemical Society