[1P-0052] Structural studies of eukaryotic MATE transporter

〇Hirotake Miyauchi¹, Tsukasa Kusakizako¹, Kaoru Kumazaki¹, Tomohiro Nishizawa¹, Ryuichiro Ishitani¹, Osamu Nureki¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0053] Crystal structures of human endothelin ETB receptor in complex with B-type selective agonists

〇Tamaki Izume¹, Wataru Shihoya², Tomohiro Nishizawa¹, Osamu Nureki¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2.Grad. Sch. of Sci., Nagoya Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0054] Structural basis for endothelin recognition by human endothelin ETB receptor

〇Wataru Shihoya^1,2,3, Tomohiro Nishizawa^3,4, Akiko Okuta², Kazutoshi Tani², Yoshinori Fujiyoshi^1,2, Osamu Nureki³, Tomoko Doi⁵ (1.Grad. Sch. of Pham., Nagoya Univ., 2.Cellular and structural physiology institute, Nagoya Univ., 3.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 4.JST PRESTO, 5.Dept. of Biol. Sci., Grad. Sch. of Sci., Kyoto Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0055] Novel approach to mechano-medicine towards development of drugs targeting the lipid-protien interactions on mechanosensitive channels

〇Hisashi Kawasaki¹, Ken-ichi Hashimoto¹, Yoshitaka Nakayama³, Yasuyuki Sawada², Kazuhiro Nobata¹, Kosuke Komazawa¹, Masahiro Sokabe², Boris Martinac³ (1.Dept. of Materials Sci., Grad. Sch. of Eng., TDU, 2.Grad. Sch. of Med., Univ. of Nagoya, 3.Victor Chang Cardiac Research Institute)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0056(2PS2-4)] Molecular mechanisms of the Lon AAA+ protease

〇Wataru Nishii¹, Mutsuko Kukimoto-Niino², Takaho Terada¹, Mikako Shirouzu², Tomonari Muramatsu¹, Toru Sengoku¹, Yoshifumi Fujii¹, Shigeyuki Yokoyama¹ (1.RIKEN Struct. Biol. Lab, 2.RIKEN CLST)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0057] Characterization of a novel Issatchenkia orientalis GPI-anchored protein involved in tolerance to low pH and salt stress

〇Akinori Matsushika^1,2, Toshihiro Suzuki¹, Kanako Negi¹, Tetsuya Goshima³, Tamotsu Hoshino^1,2 (1.ISC, AIST, 2.Grad. Sch. Adv. Sci. Mat., Hiroshima Univ., 3.NRIB)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0058] Verification of the trade-off hypothesis between the catalytic activity at a moderate temperature and the thermal stability of a thermophilic isopropylmalate dehydrogenase

〇Mizumo Bessho¹, Satoshi Akanuma², Hikono Kimura¹, Akihiko Yamagishi¹ (1.Dept. of Appl. Life Sci., Tokyo Univ. of Pharm. Life Sci., 2.Facl. Human Sci., Waseda Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0059] The contributions of phosphate group of FMN on the cofactor-binding reaction of FMN-binding protein

〇Masahiro Oda¹, Takeshi Nakanishi¹, Masaya Kitamura¹ (1.Dept. of Appl. Chem. and Bioeng., Grad. Sch. of Eng., Univ of Osaka City.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0060] Discovery of potent, reversible and specific chemical inhibitors of Midasin, an essential AAA+ protein for ribosome biogenesis

〇Shigehiro A. Kawashima^1,2, Zhen Chen², Yuki Aoi¹, Yuki Kobayashi¹, Paul Nurse^2,3, Tarun M. Kapoor² (1.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 2.The Rockefeller University, 3.The Francis Crick Institute)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0061] For efficient disaggregation, ClpB is activated by DnaK which binds a substrate

〇Sayaka Hayashi¹, Kei Kagii², Yosuke Nakazaki², Yo-hei Watanabe^1,2,3 (1.Dept. of Biol., Grad. Sch. of Nat. Sci., Konan Univ.,, 2.Dept. of Biol., Fac. of Sci. and Eng., Konan Univ.,, 3.Inst. for Integrative Neurobiol., Konan Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan