[1AS9-4] Maintenance of genome integrity: rate, causes and consequences of de novo germline mutation

〇Mizuki Ohno¹ (1.Dept. of Medical Biophysics and Radiation Biology, Faculty of Med. Sci., Kyushu Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 10:20 AM - 10:45 AM

[1AS9-5] Detection of germline spontaneous mutations by high-throughput sequencing and functional studies based on population genetics.

〇Yoichi Gondo¹ (1.RIKEN BioResource Center)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 10:45 AM - 11:10 AM

[1AS9-Conclusion] Germline mutations and organism evolution

〇Yoichi Gondo¹ (1.RIKEN BioResource Center)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 11:10 AM - 11:15 AM

[1AS10-Introduction] Molecular Mechanisms and Regulations for Construction and Structural Changes of Chromosomal Replication Machinery

〇Tsutomu Katayama¹ (1.Dept. of Mol. Biol., Grad. Sch. of Pharm. Sci., Kyushu Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 9:00 AM - 9:03 AM

[1AS10-1] Molecular mechanisms of DnaA complexes constructed on oriC and those for regulation of replication initiation at oriC

〇Tsutomu Katayama¹, Kazutoshi Kasho¹, Yukari Sakiyama¹, Yusuke Akama¹, Yukie Inoue¹, Ryuji Sakai¹, Ryo Sugiyama¹, Hironori Kawakami¹ (1.Dept. of Mol. Biol., Grad. Sch. of Pharm. Sci., Kyushu Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 9:03 AM - 9:19 AM

[1AS10-2] Near-atomic structure for bacterial DNA replication initiation complex and its functional insights

Masahiro Shimizu¹, Yasunori Noguchi², Yukari Sakiyama², Hironori Kawakami², Tsutomu Katayama², 〇Shoji Takada¹ (1.Dept. Biophys. Grad. Sch. of Sci. Kyoto Univ., 2.Dept. Mol. Biol. Grad. Sch. of Pharm. Sci. Kyushu Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 9:19 AM - 9:35 AM

[1AS10-3] Switch-like assembly of preinitiation complex in the initiation of DNA replication

Mayumi Miyazawa-Onami¹, Hiroyuki Araki^1,2, 〇Seiji Tanaka^1,2 (1.Div. Microbial Genet., Natl. Inst. Genetics, 2.SOKENDAI)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 9:35 AM - 9:51 AM

[1AS10-4] Regulation of Replication Initiation Complex Formation by Nuclear Localization in Fission Yeast

〇Hisao Masukata^1,2, Hidesato Ogawa², Haruhiko Asakawa², Tatsuro Takahashi¹, Takuro Nakagawa¹, Yasushi Hiraoka², Shiho Ogawa¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ., 2.Dept. of Biol. Sci., Grad. Front. Sci., Osaka Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 9:51 AM - 10:07 AM

[1AS10-5(2P-0111)] Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells

〇Chi-Chun Yang¹, Masahiro Suzuki¹, Shiori Yamakawa¹, Syuzi Uno¹, Ai Ishii¹, Satoshi Yamazaki¹, Rino Fukatsu¹, Ryo Fujisawa², Kenji Sakimura³, Toshiki Tsurimoto², Hisao Masai¹ (1.Dept. of Genome Med., Tokyo Metropol. Instit. Med. Sci., 2.Dept. of Biol., Facul. of Sci., Kyushu Univ., 3.Dept. of Cell. Neurobiol., Brain Res. Inst., Niigata Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 10:07 AM - 10:19 AM

[1AS10-6(3P-0106)] Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA

〇Hirokazu Nishida^1,2, Takuya Yoda³, Maiko Tanabe¹, Toshiyuki Tsuji⁴, Takao Yoda⁴, Sonoko Ishino⁵, Tsuyoshi Shirai⁴, Haruko Takeyama³, Yoshizumi Ishino⁵ (1.Hitachi, Ltd., 2.NEDO, 3.Waseda Univ., 4.Nagahama Inst. of Bio-Science and Technology, 5.Kyushu University)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 30, 2016 10:19 AM - 10:31 AM