[1SP-28-09] Molecular basis for autism caused by mutations of the chromatin remodeler CHD8

^○Taichi Shiraishi¹, Yuta Katayama¹, Masaaki Nishiyama², Kiyoe Ura³, Hirotaka Shoji⁴, Tsuyoshi Miyakawa⁴, Keiichi Nakayama¹ (1.Dept. of Mol. Cell. Biol., M.I.B., Kyushu-univ., 2.Dept. of Hist. Cell Biol., Grad. sch. of Med. Sci., Kanazawa-univ., 3.Dept. of Biol., Lab. of Chromatin Metabol. Epigene., Chiba-univ., 4.Div. of System Med. Sci., Fujita health univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-11] Analysis of pathogenesis of retinal degeneration using goldfish

^○Natsuki Noda¹, Keigo Matsuura¹, Ryota Ichikawa¹, Kota Suzuki², Atsushi Nagano³, Kentaro Fukuta⁴, Atsushi Toyoda⁵, Hideki Noguchi⁴, Tetsuo Kon¹, Yoshihiro Omori¹ (1.Grad.Sch.of Bioscience, Nagahama Inst. of Bioscience and Technology, 2.Yatomi Station, Aichi Fisheries Res. Inst., 3.Ryukoku Univ. Dept of Agriculture, 4.Joint Support-Center for Data Science Research (ROIS-DS), 5.Advanced Genomics Center, National Inst. of Genetics)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-12] The identification of specific mutations in amyloid precursor protein modulating γ-secretase cleavage.

^○Ryota Suzuki, Haruka Takahashi, Masafumi Hidaka, Tomohisa Ogawa, Eugene Futai (Dept. of Enzymology, Grad. Sch. of Agriculture, Univ. of Tohoku)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-10] Investigation on the mechanisms of disorder-like behavior seen in Importin α4/KPNA4 KO mice

^○Koki Sakurai¹, Yoichi Miyamoto², Makiko Morita¹, Tom Macpherson¹, Takaaki Ozawa¹, Yoshihiro Yoneda³, Masahiro Oka², Takatoshi Hikida¹ (1.Lab. for Adv. Brain Func., Inst. for Prot. Res., Osaka U., 2.Lab. of Neuc. Trans. Dyna., NIBIOHN, 3.Res. Found. for Microb. Dis. of Osaka U.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-13] Novel ligand screening for an orphan G protein-coupled receptor involved in neuropsychiatric disorders

^○Nanami Hoshino¹, Hiroyuki Hirano², Hiroyuki Osada^2,3, Shigeki Takeda¹ (1.Grad. Sch. of Sci. and Tech., Univ. of Gunma, 2.RIKEN・center for Sustainable Resource Sci., 3.Dept. of Pham Sci., Univ. of Shizuoka)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-14] Roles of mitochondrial localization in proteostasis decline in neurons during aging

^○Kanako Shinno¹, Emiko Suzuki^2,3,1, Yuri Miura⁴, Koichi Iijima.M^5,6, Kanae Ando^1,7 (1.Grad Sch of Sci, Tokyo Metropolitan Univ., 2.NIG, 3.Sch of Life Sci, SOKENDAI, 4.TMIG, 5.NCGG, 6.Grad Sch of Pharm Sci, Nagoya City Univ., 7.Sch of Sci, Tokyo Metropolitan Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-15] Generation of a-synuclein mutant protein library to screen amino acids responsible for aggregation

^○Tomoyuki Yamanaka^1,2, Akiko Hiyama², Hideaki Matsui¹, Nobuyuki Nukina² (1.Brain Res. Inst., Niigata Univ., 2.Doshisha Univ. Grad Sch. Brain Sci.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-16] Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability

^○Takumi Taketomi¹, Takunori Yasuda², Rikuri Morita³, Yasuteru Shigeta³, Ryuhei Harada³, Fuminori Tsuruta^4,1 (1.PhD. Prog. in Hum. Biol., Grad. Sch. of Comp. Hum. Sci., Univ. of Tsukuba, 2.PhD. Prog. in Biol., Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba, 3.Center for Comp. Sci., Univ. of Tsukuba, 4.Fac. of Life and Env. Sci., Univ. of Tsukuba)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-17] The Role of Exosome in the Etiology and Diagnosis of Autism Spectrum Disorder

^○Kei Sugiura, Mantaro Kawaguchi, Ayuko Hoshino (Dept. of Life Sci. and Tech., Sch. of Life Sci. and Tech., Tokyo Inst. of Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1SP-28-18] Screening of lipid species and associated enzymes that participate in α-synuclein aggregation.

^○Ryota Kasahara, Jun Ogata, Kenta Shiina, Kahori ShibaFukushima, Tsuyoshi Inoshita, Nobutaka Hattori, Yuzuru Imai (Dept. of Neur., Grad. Sch. of Med., Juntendo Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan