[2P-681] Development and use of a kinetical and real-time monitoring system to analyze the replication of hepatitis C virus and related flaviviruses

^○Masahiko Ito¹, Xiaoyu Li¹, Haruyo Aoyagi², Murayama Asako², Kwangsu Kim³, Toru Takada⁴, Ryosuke Suzuki², Shingo Iwami³, Koichi Watashi⁵, Takanobu Kato², Hideki Aizaki², Tetsuro Suzuki¹ (1.Dept. of Virol. and Parasitol., Hamamatsu Univ. Sch. of Med., 2.Dept. of Virol II, NIID, 3.iBLab, Div. of Biol. Sci., Nagoya Univ., 4.Dept. of Biol., Facul. of Sci., Kyushu Univ., 5.Res. Cent. for Drug and Vac. Dev., NIID.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-682] Ontological description modeling of cellular senescence processes

^○Yuki Yamagata^1,2, Hiroshi Masuya^3,2, Shuichi Onami^1,2 (1.RIKEN BDR, 2.RIKEN R-IH, 3.RIKEN BRC)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-683] Gain of function mutation in chondroitin polymerizing factor, MIG-22, delays aging and extends lifespan

^○Yukimasa Shibata¹, Yuri Tanaka¹, Shion Fujii¹, Toshihiro sassa², Hidenao Toyota³, Kiyoji Nishiwaki¹ (1.Dept. of Biomed. Sci., Sch. of Biol, and Env. Sci., Kwansei Gakuin Univ.,, 2.CDB, RIKEN, 3.Depart.of Pharm. Sci., Fac. of Pharm. Sci., Ritsumeikan Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-684] Analysis of senescent marker p16INK4a expression-associated cluster gene regulation aroused physiological aging

^○Yuma Sugiyama¹, Tanenobu Harada¹, Akihiko Nishikimi², Mitsuo Maruyama^1,3 (1.Dept. of Infla. and Immunosene., Gerosci. Res. Cent., Res. Inst., Natio. Cent. for Geriat. and Gero., 2.Biosafety Div., Res. Inst., Natio. Cent. for Geriat. and Gero., 3.Dept. of Aging Res., Grad. Sch. of Med., Univ. of Nagoya)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-685] Identification and functional analysis of proteins and RNAs in senescence-associated aggregate

^○Yasuhiro Takenaka^1,2, Masataka Hirasaki³, Ikuo Inoue², Masaaki Ikeda⁴, Yoshihiko Kakinuma¹ (1.Dept. of Physiol., Nippon Med. Sch., 2.Dept. of Diabetes and Endocrinol., Saitama Med. Univ., 3.Dept. of Clinical Cancer Genomics, Saitama Med. Univ., 4.Dept. of Physiol., Saitama Med. Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-686] ST6GAL1 sialyltransferase, a potential player in epidermal stem cell aging

^○Thi Kim Nguyen Nguyen¹, Raja Erna^1,2, Oinam Lalhaba³, Xuan Ngo Yen¹, Yanagisawa Hiromi^2,4, Tateno Hiroaki³, Sada Aiko^1,2 (1.International Research Center for Medical Sciences, Kumamoto Univ., 2.Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), Univ. of Tsukuba, 3.Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Japan, 4.Faculty of Medicine, Univ. of Tsukuba)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-687] Changes in characteristics of murine hair follicles through the lifetime and tissue stem cells

^○Kimihiko Sugaya (Dept. of Mol. Imaging and Theranostics, Inst. for Quant. Med. Sci., QST)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-688] Royal jelly maintains epidermal stem cell-properties by repressing senescence

^○Saya Goto¹, Mariko Moriyama¹, Yuko Miyake¹, Tomomi Degawa^2,3, Nobuaki Okumura^2,3, Hiroyuki Moriyama¹ (1.Pharm. Res. Technol. Inst., Kindai Univ., 2.Inst. Bee Prod.& Health Sci., Yamada Bee Company, Inc., 3.Gr. Cosmetic Central Lab., Yamada Bee Company, Inc.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-689] Physiological elucidation of senescent cells in skin aging using novel senolytic mouse model

^○Tanenobu Harada¹, Yuma Sugiyama¹, Yu Aoki², Yuka Kamei¹, Keiko Tsuji², Daijirou Sugiyama², Mitsuo Maruyama^1,3 (1.DII., GSRC., NCGG, 2.DSHC, 3.Dept.Aging., Grad. Sch. Med., Nagoya Univ)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-690] Mechanisms of adrenal aging and enhancement of the Glucocorticoid-system

^○Noriyuki Okudaira¹, MiHo Akimoto¹, Takao Susa¹, Miho Akimoto¹, Yukihiro Kohara¹, Harumi Hisaki¹, Masayoshi Iizuka², Tomoki Okazaki¹, Mimi TamamoriAdachi¹ (1.Dept. of Biochem., Teikyo Univ. Sch. of Med, 2.Med. Edu. Centre., Teikyo Univ. Sch. of Med)

The 45th Annual Meeting of the Molecular Biology Society of Japan