[2P-751] Wnt activation-induced disturbance of cell competition causes diffuse invasion of transformed cells through NF-κB-mediated MMP21 upregulation.

^○Kazuki Nakai¹, Hancheng Lin¹, Shinya Tanaka², Yoku Hayakawa³, Yasuyuki Fujita⁴, Shunsuke Kon¹ (1.Div. of Mol. Biol., Div. of Cancer Cell Biol., RIBS., TUS., 2.Div. of Mol. Oncology, IGM., Hokkaido Univ., 3.Dept. of Gastroenterology, The Univ. of Tokyo, 4.Dept. of Molecular Oncology, Grad. Sch. of Med., Kyoto Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-752] Mechanism of anticancer activity of kaurenoic acid derivatives to identify their target molecules

^○Kyosuke Egashira¹, Norika Tanaka², Hiroshi Takemori^2,1 (1.Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, 2.Department of Life Science and Chemistry, Graduate School of Natural Science and Technology, Gifu University)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-753] Impact of ARID1A Loss-of-function mutation on DNA methylation and gene regulation in cancer molecular subtype

^○Ryoji Fujiki^1,2, Norikazu Yogi¹, Genki Usui¹, Bahityar Nawai¹, Shin Matsumoto¹, Tianhui Zhu¹, Atsushi Okabe¹, Atsushi Kaneda^1,2 (1.Dept. of Mol. Oncol., Grad. Sch. of Med., Chiba Univ., 2.CGC, Chiba Univ. Hosp.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-754] Elucidation of the pathophysiological roles of O-linked glycosylated GRP78/Bip on breast cancer cell proliferation

^○Kosei Hagiwara, Keiji Uchiyama, Tetsuro Yoshimaru, Yosuke Matsushita, Toyomasa Katagiri (Div. Genome Med., Inst. Advanced Med. Sci., Tokushima Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-755] Pan-cancer analysis of the association between silent mutation and cancer pathogenesis

^○Chie Kikutake, Mikita Suyama (Div. of Bioinfo, MIB, Kyushu Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-756] Generation and analysis of bispecific antibodies against human cancer antigens and T cell antigen CD3 using a cell fusion method

^○Honoka Yamamoto¹, KanIchiro Ihara^2,1, Takeshi Nakanishi^2,1, Chikako Yokoyama^2,1, Taro Tachibana^1,2 (1.Dept. of Appl. Chem. Bioeng., Grad. Sch. of Eng., Osaka city Univ., 2.Dept. of Appl. Chem. Bioeng., Grad. Sch. of Eng., Osaka Metropol Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-757] Screening of epigenetic regulators relating to drug resistance in lung cancer cells

^○Akihiko Ishimura^1,2, Gerelsuren Batbayar¹, Hanbing Lyu¹, Sasithorn Wannaudom¹, Suphakhong Kusuma¹, Minoru Terashima^1,2, Seiji Yano^1,3, Takeshi Suzuki^1,2 (1.Div. Functional Genomics, Cancer Res. Inst., Kanazawa Univ., 2.Unit Mol. Therapeutic Target, Inst. Frontier Sci. Initiative, Kanazawa Univ., 3.Fac. Med., Inst. of Medical, Pharmaceutical and Health Sci.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-758] Relationship between the proto-oncogene product FLI1 and the oncogenic potential of Ewing's sarcoma.

^○Runa Sato, Kazuo Kamemura (Grad. Sch. of Biosci., Nagahama Inst. of Bio-Sci. & Technol.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-759] The effect of KRAS inhibitors on hypoxic related factors in cancers

^○Noritaka Tanaka, Takeharu Sakamoto (Dept. of Cancer Biol., Inst. of Biomed. Sci, Kansai Med. Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-760] Induction of genes encoding Turandot peptides dependent on JAK/STAT signaling and their anti-tumor effects in Drosophila mxc hematopoietic tumor mutants

^○Yuriko Kinsohita, Naoka Shiratsuchi, Yoshihiro Inoue (Biomedical Res.Ctr.,Kyoto Inst. Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan