[3SP-28-09] Tumor-specific immune activation mechanism in radiotherapy using alpha-emitting radionuclides

^○Koki Mayusumi¹, Kazuya Kabayama^1,2,3, Xuhao Huang¹, Kazuko Kaneda^2,3, Atsushi Toyoshima^2,3, Koichi Fukase^1,2,3 (1.Dept. of Chem., Grad. Sch. of Sci., Osaka Univ., 2.FRC, Grad. Sch. of Sci., Osaka Univ., 3.Inst. for Radiation Sciences, Osaka Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-10] Estimation of curative effects in stereotactic body radiotherapy for lung cancer based on a theoretical model considering cancer stem-like cells for predicting radiosensitivity

^○Ryo Saga¹, Yusuke Matsuya², Hikari Sato¹, Kazuki Hasegawa¹, Hideki Obara³, Fumio Komai³, Hironori Yoshino¹, Hiroyuki Date², Masahiko Aoki⁴, Yoichiro Hosokawa¹ (1.Dept. of Radiat. Sci., Grad. Sch. of Health Sci., Hirosaki Univ., 2.Fac. of Health Sci., Hokkaido Univ., 3.Dept. of Radiol., Div. of Med. Technol., Hirosaki Univ. Hosp., 4.Dept. of Radiat. Oncol., Grad. Sch. of Med., Hirosaki Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-11] Synthesis and evaluation of XIAP inhibitors designed by structural optimization of lead compounds using AI technology

^○Koutaro Sasaki¹, Kouji Kuramochi², Atsushi Yoshimori³, Ryoko Takasawa^4,1 (1.Dept. Pharm. Sci., Grad. Sch. Pharm. Sci., Tokyo Univ. Sci., 2.Facul. Sci. Tech., Tokyo Univ. Sci., 3.ITM, Inc., 4.Facul. Pharm. Sci., Tokyo Univ. Sci.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-12] Anticancer drug bleomycin does not cause fibrosis under cytotoxic dominance in the lung
～Evaluation of anticancer drug using precision-cut lung slices, PCLS～

^○Yoko Miura, Satoshi Kanazawa (Dept. of Neu. Disorder Genet.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-13] Retroviral replicating vector-mediated suicide gene therapy for osteosarcoma

^○Ayane Kawabe^1,2, Hiroaki Fujino^1,2, Emiko Sonoda¹, Yuya Takeuchi^1,2, Toru Takarada³, Noriyuki Kasahara⁴, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-07] Suicide gene therapy by retroviral replicating vectors for canine malignancies

^○Emiko Sonoda¹, Hiroaki Fujino^1,2, Ayane Kawabe^1,2, Yuya Takeuchi^1,2, Toru Takarada³, Shunsuke Noguchi⁴, Noriyuki Kasahara⁵, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Lab. of Vet. Radio., Grad. Sch. of Vet. Sci., Osaka Metropolitan Univ., 5.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-14] ACA-28 and the derivative ACAGT-007a induce apoptosis by further activating ERK MAPK signaling in cancer cells

^○Ryosuke Sato, Golam Iftakhar Khandakar, Fumihiro Ishikawa, Teruaki Takasaki, Genzoh Tanabe, Reiko Sugiura (Fac. of Pharm., Kindai Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-15] Functional analysis of novel modifications of microRNAs in pancreatic cancer.

^○Mayuka Ohkawa¹, Takahito Ohshiro², Jun Koseki³, Shunsuke Kon¹, Masateru Taniguchi², Teppei Shimamura³, Masamitsu Konno¹ (1.Grad. Sch. of Biol. Sci., Tokyo Univ. of Sci., 2.Sanken., Osaka Univ., 3.Grad. Sch. of Med., Nagoya Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-16] Investigation of novel radiosensitizing strategy against radioresistant cancer cells via hyaluronan synthase 3 suppression

^○Kazuki Hasegawa, Ryo Saga, Eichi Tsuruga, Yoichiro Hosokawa (Dept. of Radiat Sci., Grad. Sch. of Health Sci., Univ. of Hirosaki)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3SP-28-17] Interleukin-15 derived from Guanylin-Guanylase Cyclase C-expressing macrophages inhibits fat accumulation in adipocytes.

^○SAYAKA AKIEDA, FUMITAKE YAMAGUCHI, YUKARI DATE (Frontier Science Research Center, Univ. of Miyazaki)

The 45th Annual Meeting of the Molecular Biology Society of Japan