[1P-220] Tardigrade-unique tolerance protein CAHS forms filaments via electrostatic interaction and stiffens cells in response to hyperosmotic stress.

^○Akihiro Tanaka¹, Gen Honda², Miho Yanagisawa², Takekazu Kunieda¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2.Dept. of Basic Sci., Grad. Sch. of Arts and Sci., Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-221] Tfs1/TFIIS-dependent transcription causes gross chromosomal rearrangements through DNA-RNA hybrid formation at centromeres

^○Ran Xu^1,2, Crystal Tang¹, Takuro Nakagawa^1,2 (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ., 2.Forefront Res. Cent., Grad. Sch. of Sci., Osaka Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-222] Werner helicase and MutLα endonuclease control the fidelity of single-strand annealing

^○Yoshitaka Kawasoe¹, Satomi Oda², Aya Sakazume³, Ryoko Hisamochi³, Tatsuro Takahashi¹ (1.Div. of Biol., Fac. of Sci., Kyushu Univ, 2.Dept. of Biol., Grad. Sch. of Sci., Osaka Univ, 3.Grad. Sch. of Systems Life Sci., Kyushu Univ)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-223] The sustainment of chronological lifespan by mitochondrial homologous DNA pairing-promoting protein Mhr1 in budding yeast

^○LING Feng¹, ZHU Wenjuan^1,2, MATSUMOTO Ken¹, YOSHIDA Minoru^1,2,3 (1.Chem. Genomics Res. Gr., RIKEN CSRS, 2.Dept. Biotechnol., Univ. Tokyo, 3.CRIIM, Univ. Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-224] Molecular Analysis of Rad50 Adenylate Kinase Activity in the Mre11-Rad50-Nbs1-Ctp1 Complex that functions at the Initial Step of Homologous Recombination

^○Niu Jia Hao¹, Zdravkovic Aleksandar², Kanamaru Shuji¹, Tsubouchi Hideo², Iwasaki Hiroshi^2,1 (1.Dept. of Life Sci. and Tech., Grad. Sch. of Life Sci. and Tech., Tokyo Inst. of Tech., 2.Cell Bio. Cntr., Inst. of Innov. Res., Tokyo Inst. of Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-225] Regulatory mechanism of homologous recombination repair by the ubiquitylation of DNA-RNA helicase DHX9

^○Komei Takimoto¹, Yuina Tsuchiya¹, Saaya Matsuya¹, Hayaki Ikegame², Ryotaro Nishi^1,2 (1.Mol. Biol. Lab., Grad. Sch. Bionics, Tokyo Uni. Tech., 2.Mol. Biol. Lab., Sch. Biosci. Biotech., Tokyo Uni. Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-226] Analysis of the mechanism of anti-recombination by in vitro reconstitution

^○Ryoko Hisamochi¹, Aya Sakazume¹, Yoshitaka Kawasoe², Tatsuro Takahashi² (1.Grad. Sch. of Systems Life Sci., Kyushu Univ., 2.Div. of Biol., Fac. of Sci., Kyushu Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-227] Functional discrimination of DNA binding sites of human RAD52 protein in DNA double-strand break repairs

Nakako Nakajima¹, Wataru Kagawa², Tomoko Yanaka³, Takaya Gotoh⁴, Yuka Nakazawa⁵, Tomoo Ogi⁵, Tajima Katsushi⁶, ^○Takeshi Yasuda³ (1.iQMS, QST, 2.Dept. of Chem., Grad. Sch. Sci. Eng., Meisei Univ., 3.iQLS, QST, 4.Dept. of Heal. Sci., Daito Bunka Univ., 5.Dept. of Genet., RIeM, Nagoya Univ., 6.Dept. of Hemat., Yamagata Prefect. Central Hospital)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-228] New functional analysis of DGCR8 against the oxidative stress induced by UV-A irradiation in normal human dermal cells.

^○Kaisei Hoshiai¹, Takaaki Watanabe², Toshiyasu Taniguchi² (1.Dept. of Mol. Life Sci., Sch., of Med., Tokai Univ., 2.Tokai Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-229] Functional analysis of the domain regulating DExH Box Helicase DHX9 dynamics in homologous recombination

^○Yuina Tsuchiya¹, Hayaki Ikegame², Yurina Abe², Ryotaro Nishi^1,2 (1.Mol. Biol. Lab., Grad. Sch. Bionics, Tokyo Uni. Tech., 2.Mol. Biol. Lab., Sch. Biosci. Biotech., Tokyo Uni. Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan