[3PW-05-6] NGLY1 deficiency

^○Tadashi SUZUKI (RIKEN, CPR; T-CiRA Program)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 5:30 PM - 5:49 PM

[3PW-05-7] Development of novel in vivo therapy for lysosomal neuraminidase1 deficiencies

^○Kohji Itoh, Jun Tsukimoto, Mizuki Miyoshi, Rin Fukuike (Dept. of Medicinal Biotechnol., Grad Sch. of Pharmaceut. Sci., Tokushima Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 5:49 PM - 6:08 PM

[3PW-05-8] Diagnosis and treatment of inherited GPI deficiency

^○Yoshiko Murakami (RIMD, Osaka Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 6:08 PM - 6:27 PM

[3PW-05-Discussion] Discussion

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 6:27 PM - 6:43 PM

[3PW-05-Conclusion] Conclusion

^○Yoshiko Murakami¹, Shoko Nishihara² (1.Osaka University, 2.Soka University)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 6:43 PM - 6:45 PM

[3AW-06-1] Targeting the GTP-Energy Metabolism as the Next-Generation Therapeutics

^○Atsuo Sasaki^1,2 (1.University of Cincinnati College of Medicine, 2.Institute of Advanced Lifesciences， Keio University)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 9:00 AM - 9:25 AM

[3AW-06-2] Elucidating GTP sensor regulatory network that reconciles the imbalance of metabolism and its association with human phenotypic traits

^○Risa Kawaguchi (CiRA, Univ. of Kyoto)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 9:25 AM - 9:50 AM

[3AW-06-3] IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia

^○Xiaoxiao Liu¹, Naru Sato², Tomohiro Yabushita², Moe Tamura², Shuhei Asada², Takeshi Fujino², Tsuyoshi Fukushima², Taishi Yonezawa², Yosuke Tanaka², Tomofusa Fukuyama², Akiho Tsuchiya², Shiori Shikata², Hiroyuki Iwamura³, Chieko Kinouchi⁴, Kensuke Komatsu⁴, Satoshi Yamasaki⁵, Tatsuhiro Shibata⁵, Atsuo Sasaki⁶, Yuki Sugiura⁷, Hitoshi Takizawa⁸, Takuma Shibata⁹, Kensuke Miyake⁹, Toshio Kitamura², Susumu Goyama² (1.Dvi. of Mol. Oncol., Dept. of CBMS, Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2.Div. of Cell. Therapy, IMSUT, 3.FUJIFILM Corp. Pharm. PD. Div., 4.FUJIFILM Corp. Pharm.&Healthcare Res. Lab, 5.Lab of Mol. Med., Human Genome Center, IMSUT, 6.Div. of Hem. and Onocol., Dept. of Internal Med., Univ. of Cincinnati, 7.Sch. of Med. Dept.t of Biochemistry, Keio Uni., 8.Lab. of Stem Cell Stress, IRCMS, Kumamoto Uni., 9.Div. of Infectious Genetics, Dept. of Microbiology & Immunology, IMSUT)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 9:50 AM - 10:15 AM

[3AW-06-4] Development of inhibitors that target the GTP energy system

^○Koh Takeuchi (Dept. of Phys. Chem., Grad. Sch. of Sci., Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 10:15 AM - 10:40 AM

[3AW-06-5] Metabolic regulation by the GTP sensor PI5P4Kβ: towards the treatment of diabetes, cancer cachexia and sarcopenia.

^○Yoshihisa Hirota^1,2, Mika Sasaki², Jennifer Schurdak², Tatsuyoshi Kono³, Takahisa Nakamura^4,2, Koh Takeuchi⁵, Toshiya Senda⁶, Atsuo Sasaki^7,2 (1.Department of Bioscience and Engineering, Shibaura Institute of Technology, 2.University of Cincinnati College of Medicine, 3.Indiana University School of Medicine, 4.Cincinnati Children's Hospital Medical Center, 5.Graduate School of Pharmaceutical Sciences, the University of Tokyo, 6.KEK, IMSS, SBRC, 7.IAB, Keio Univ)

The 45th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2022 10:40 AM - 11:05 AM