[1P-702] Hypothalamic amino acid sensing controls glucose and bone homeostasis

^○Kazuya Fukasawa, Gyujin Park, Eiichi Hinoi (Dept. of Bioactive Molecules, Gifu Pharmaceut. Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-703] The effect of 2-carba-cyclic phosphatidic acid on the communication between astrocyte and microglia

^○Rino Takei¹, Misaki Endo¹, Mari Nakashima¹, Kei Hashimoto², Mari Gotoh³, Yasunori Miyamoto^1,3, Kimiko Murohushi⁴ (1.Div. of Life Sci., Grad. Sch. of Humani and Sci., Ochanomizu Univ. Otsuka, Bunkyo-ku, Tokyo, Japan, 2.Academic Production, Ochanomizu Univ., Otsuka, Bunkyo-ku, Tokyo, Japan, 3.IHLS, Ochanomizu Univ., Otsuka, Bunkyo-ku, Tokyo, Japan, 4.Res. Div. of Human Welfare Sci., Ochanomizu Univ., Otsuka, Bunkyo-ku, Tokyo, Japan)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-704] Molecular basis for autism caused by mutations of the chromatin remodeler CHD8

^○Taichi Shiraishi¹, Yuta Katayama¹, Masaaki Nishiyama², Kiyoe Ura³, Hirotaka Shoji⁴, Tsuyoshi Miyakawa⁴, Keiichi Nakayama¹ (1.Dept. of Mol. Cell. Biol., M.I.B., Kyushu-univ., 2.Dept. of Hist. Cell Biol., Grad. sch. of Med. Sci., Kanazawa-univ., 3.Dept. of Biol., Lab. of Chromatin Metabol. Epigene., Chiba-univ., 4.Div. of System Med. Sci., Fujita health univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-705] Search for fungal metabolites that inhibit oncogenic NF-κB signaling

^○Shinya Ohata¹, Ishikawa Kazuki¹, Masaki Ishii¹, Takashi Yaguchi², Koji Ichinose¹ (1.Res. Inst. of Pharm. Sci., Facul. of Pharm., Musashino Univ., 2.Med. Mycol. Res. Cent., Chiba Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-706] Analysis of pathogenesis of retinal degeneration using goldfish

^○Natsuki Noda¹, Keigo Matsuura¹, Ryota Ichikawa¹, Kota Suzuki², Atsushi Nagano³, Kentaro Fukuta⁴, Atsushi Toyoda⁵, Hideki Noguchi⁴, Tetsuo Kon¹, Yoshihiro Omori¹ (1.Grad.Sch.of Bioscience, Nagahama Inst. of Bioscience and Technology, 2.Yatomi Station, Aichi Fisheries Res. Inst., 3.Ryukoku Univ. Dept of Agriculture, 4.Joint Support-Center for Data Science Research (ROIS-DS), 5.Advanced Genomics Center, National Inst. of Genetics)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-707] The identification of specific mutations in amyloid precursor protein modulating γ-secretase cleavage.

^○Ryota Suzuki, Haruka Takahashi, Masafumi Hidaka, Tomohisa Ogawa, Eugene Futai (Dept. of Enzymology, Grad. Sch. of Agriculture, Univ. of Tohoku)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-708] Metabolic symptoms of autism spectrum disorder-related gene Kmt2c mutant mice

^○Kazuki Harada¹, Yuri Osuga¹, Takumi Nakamura², Kurara Takano², Tadafumi Kato³, Atsushi Takata², Takashi Tsuboi¹ (1.Dept. Life Sci., Grad. Sch. Art. Sci., Univ. Tokyo, 2.Lab for Mol. Path. Psychiatric Disord., CBS, RIKEN, 3.Dept. Mol. Path. Mood Disord., Junitendo Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-709] Motivational increase and brain network variation in Importinα3/KPNA3 deficient mice

^○Yoshiatsu Aomine^1,2, Koki Sakurai¹, Tom Macpherson^1,2, Takaaki Ozawa^1,2, Yoichi Miyamoto³, Yoshihiro Yoneda⁴, Masahiro Oka³, Takatoshi Hikida^1,2 (1.Lab for Advanced Brain Functions, Inst. for Protein Res., Osaka Univ., 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ., 3.Lab of Nuclear Transport Dynamics, Nat. Inst. of Biomedical Innovation, Health and Nutrition (NIBIOHN), 4.The Res. Found. for Microbial Diseases of Osaka Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-710] Investigation on the mechanisms of disorder-like behavior seen in Importin α4/KPNA4 KO mice

^○Koki Sakurai¹, Yoichi Miyamoto², Makiko Morita¹, Tom Macpherson¹, Takaaki Ozawa¹, Yoshihiro Yoneda³, Masahiro Oka², Takatoshi Hikida¹ (1.Lab. for Adv. Brain Func., Inst. for Prot. Res., Osaka U., 2.Lab. of Neuc. Trans. Dyna., NIBIOHN, 3.Res. Found. for Microb. Dis. of Osaka U.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-711] Hypomyelinating leukodystrophy 8 (HLD8)-associated mutation of POLR3B leads to defective oligodendroglial morphological differentiation whose effect is reversed by ibuprofen.

^○Sui Sawaguchi¹, Remina Shirai², Junji Yamauchi² (1.Lab. of Molecular Neurol., Dept. of Life Sci., Grad. Sch. of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., 2.Lab. of Molecular Neurol., Tokyo Univ. of Pharmacy and Life Sci.)

The 45th Annual Meeting of the Molecular Biology Society of Japan