[2P-077] Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up

^○Nasti Alessandro¹, Sakai Yoshio², Takeshita Yumie³, Okumura Miki³, Kitajima Shinji⁴, Honda Masao², Wada Takashi⁴, Nakamura Seiji⁵, Takamura Toshinari³, Tamura Takuro⁶, Matsubara Kenichi⁷, Kaneko Shuichi^1,2 (1.Information-Based Medicine Development, Grad. Sch. of Medical Sciences, Kanazawa Univ., Kanazawa, Japan., 2.Dept. of Gastroenterology, Kanazawa Univ. Hospital, Kanazawa, Japan, 3.Dept. of Endocrinology and Metabolism, Grad. Sch. of Medical Sciences, Kanazawa Univ., Kanazawa, Japan, 4.Dept. of Nephrology and Laboratory Medicine, Kanazawa Univ., Kanazawa, Japan, 5.DNA Chip Research Inc., Tokyo, Japan, 6.Research and Development Center for Precision Medicine, Univ. of Tsukuba, Tsukuba, Japan, 7.iLAC Co., Ltd., Tsukuba, Japan)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-078] The gene expression and epigenetic regulation of individual nuclei within the same multinucleated osteoclast is heterogeneous: Evidence from Intra-single cell sequencing (iscSeq)

^○Okada Hiroyuki^1,2, Terui Yuta³, Omata Yasunori^2,4, Tani Shoichiro^1,2, Terashima Asuka⁴, Saito Taku², Baron Roland^2,5, Tanaka Sakae², Chung Ungil^1,6, Hojo Hironori^1,6 (1.Cent. of Disease Biol., Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Orthop. Surg., Grad. Sch. of Med., Univ. of Tokyo, 3.Biotech. Sect. 1, Product Strategy Dept., Marketing Cent., Life Business HQ, Yokogawa Electric Corp., 4.Bone and Cartilage Rege. Med., Univ. of Tokyo Hosp., 5.Dept. of Oral Med., Infection, and Immunity, Harvard Sch. of Dental Med., 6.Dept. of Bioengi., Grad. Sch. of Engine., Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-079] Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS

^○Tomoyuki Nanamiya¹, Kiyoko Takane¹, Kiyoshi Yamaguchi¹, Tsuneo Ikenoue¹, Tomoko Fujiyuki², Misako Yoneda³, chieko Kai², Yoichi Furukawa¹ (1.Div. Clin. Genome Res., Inst. Med. Sci., Univ. of Tokyo, 2.Infect. Des. Contr. Sci., Indust. Sci., Univ. of Tokyo, 3.Div. of Viro. Med, Indust. Sci., Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-080] A CNC-family transcription factor Nrf3 coordinates melanogenesis cascade through macropinocytosis and autophagy regulation

^○Ayaka Wada¹, Sota Nakada², Haruka Masuda¹, Haruna Sumi², Shuuhei Hirose¹, Iori Aketa¹, Tsuyoshi Waku², Akira Kobayashi^1,2 (1.Grad. Sch. of Life & Med. Sci., Doshisha Univ., 2.Fac. of Life & Med. Sci., Doshisha Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-081] RNA methylation regulates the gene expression program in epithelial-mesenchymal transition of cancer cells

^○Takeshi Suzuki^1,2, Kusuma Suphakhong¹, Minoru Terashima^1,2, Sasithorn Wannaudom¹, Risa Takatsuka¹, Akihiko Ishimura^1,2, Matomo Sakari³, Toshifumi Tsukahara³ (1.Div. Func. Genom., Cancer Res. Inst., Kanazawa Univ., 2.Mol. Therap. Target Res. Unit, InFIniti, Kanazawa Univ., 3.Area. Biosci. Biotech., Div. Transdis. Sci., JAIST)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-082] Identification of aberrant transcription termination at specific gene loci with DNA hypomethylated transcription termination sites caused by DNA methyltransferase deficiency

^○Masaki Shirai¹, Takuya Nara², Haruko Takahashi^1,2, Kazuya Takayama¹, Yuan Chen², Yudai Hirose², Masashi Fujii², Akinori Awazu², Nobuyoshi Shimoda³, Yutaka Kikuchi^2,1 (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Hiroshima, 2.Grad. Sch. of Integr. Sci. for Life, Univ. of Hiroshima, 3.Div. Mol. Anal., Ctr. for Core Facility Admin., Natl. ctr. for Geriat. and Gerontol.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-083] Molecular mechanisms of heat response by HSFA family in Arabidopsis thaliana

^○Tatsuya Hongo, Nobutoshi Yamaguchi, Toshiro Ito (NAIST)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-084] Molecular mechanism of heat response regulated by variants of the heat shock transcription factor HSFA2

^○Nagisa Miyajima, Nobutoshi Yamaguchi, Toshiro Ito (NAIST)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-085] Elucidation of nectary developmental control by MYB

^○Asumi Nagamori, Seika Togawa, Nobutoshi Yamaguchi, Toshiro Ito (NAIST biol)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[2P-086] Role of TFIID subunit TAF7 in regulation of transcription bursting

^○Kazuki Furugori, Hidefumi Suzuki, Ryota Abe, Hidehisa Takahashi (Dept. of Mol. Biol., Grad. Sch. of Med., Yokohama City Univ)

The 45th Annual Meeting of the Molecular Biology Society of Japan