[1P-456] Ndc80-dependent mechanisms for spindle bipolarization during meiosis I in mouse oocytes

^○Shuhei Yoshida, Tomoya Kitajima (BDR, RIKEN)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-457] COPII that facilitates the anterograde vesicle transport is required for cytokinesis in Drosophila male meiosis

^○Yoshiki Matsuura, Kana Kaizuka, H. Yoshihiro Inoue (Biomedical Res. Ctr., Kyoto Inst. Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-458] Genetic analysis about subcellular localization of Cyclin B and roles of Mei-P26 in meiotic initiation in Drosophila males

^○Yuri Tanaka, Mai Oda, Yoshihiro H. Inoue (Biomedical Res. Ctr., Kyoto Inst. Tech.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-459] A novel method for determination of intracellular pH regulation genes under acidic circumstances

^○Hiroko Fukuda¹, Kazuya Sumida¹, Takanori Hideshima², Hirotada Mori³, Mikio Nakajima⁴, Masakazu Kataoka¹ (1.Dept. Biom. Eng., Grad. Sch., Shinshu Univ., 2.Dept. Eng. Shinshu Univ., 3.Guangdong Acad. Agr. Sci., 4.MSL Corp.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-460] 2- Deoxy- D- glucose induces deglycosylation of proinflammatory cytokine receptors and reduces LPS-induced pulmonary inflammation in mouse models of acute respiratory distress syndrome.

^○Ikuno Uehara, Mitsuko Kajita, Nobuyuki Tanaka (Inst. Adv. Med.Sci., Nippon Med. Sch.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-461] CRISPR-dCas9-based inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by the downregulation of RNA translational efficiency

^○Kazuma Nakatani^1,2, Hiroyuki Kogashi^1,2, Tetsushi Sakuma³, Takashi Yamamoto³, Yoshitaka Hippo^1,2, Yusuke Suenaga² (1.Grad. Sch. of Med. & Pharm. Sci, Chiba Univ., 2.Dep. Mol. Carcin. Chiba Cancer Ctr. Res. Ins., 3.Grad. Sch. of Integr. Sci. for Life, Hiroshima Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-462] MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway

^○XIAOYAN SHI¹, Naoko Hashimoto¹, Kazuyuki Yamagata¹, Masataka Yokoyama¹, Naohiko Seki², Tomoaki Tanaka¹ (1.Dept. of Mol. Diag., Grad, Sch, of Med., Chiba Univ, 2.Dept. of Fxnl. Genomics, Grad, Sch, of Med., Chiba Univ)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-463] The combined administration of ascorbic acid and copper induces systemic oxidative stress and renal cell injury

^○Jiang Rui, Sui Yang, Yao Jian (Dept. of BioMed. Res., Univ. of Yamanashi)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-464] Integrating cell fate prediction by image-based deep learning and single-cell transcriptomics for comprehensive and quantitative understanding of the point of no return to cell death induced by stress

^○Tomoaki Okaniwa^1,2, Katsuyuki Shiroguchi¹ (1.RIKEN BDR, 2.Grad. Sch. Frontier Biosciences, Osaka Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-465] Förster resonance energy transfer-based kinase mutation phenotyping reveals an aberrant facilitation of CaMKIIalpha activity in de novo mutations related to intellectual disability

^○Hajime Fujii¹, Hiroyuki Kidokoro², Yayoi Kondo¹, Masahiro Kawaguchi², Shinichiro Horigane^3,4, Jun Natsume^2,5, Sayaka TakemotoKimura^3,4, Haruhiko Bito¹ (1.Dept. of Neurochem, Grad. Sch. of Medicine, The Univ. of Tokyo, 2.Dept. of Pediatrics, Nagoya Univ. Grad. Sch. of Medicine, 3.Dept. of Neuroscience I, RIEM, Nagoya Univ., 4.Molecular/Cellular Neuroscience, Nagoya Univ. Grad. Sch. of Medicine, 5.Dept. of Developmental Disability Medicine, Nagoya Univ. Grad. Sch. of Medicine)

The 45th Annual Meeting of the Molecular Biology Society of Japan