[1P-1209] Screening of chemical compounds to restore the gene expression of mitochondrial chaperone reduced by neurotoxicity of αsynuclein in Drosophila

〇Yoshiki Takamatsu¹, Hiromi Akagawa¹, Masaaki Waragai^1,2, Satoshi Inoue³, Makoto Hashimoto¹ (1.Lab. Parkinson's Dis., Tokyo Metro. Inst. Med. Sci., 2.Dept. Neurol., Higashi Matsudo Municipal HP., 3.Dept. Funct. Biogerontol., Tokyo Metropol. Inst. Gerontol.)

ConBio2017

[1P-1210] Oligodendrocytes and oligodendrocyte precursor cells produce amyloid–β and express different isoforms of amyloid precursor protein.

〇Misaki Hida¹, Takakuni Maki², Megumi Asada¹, Ryosuke Takahashi², Ayae Kinoshita¹ (1.Dept. of Human Health Sci., Grad. sch. of Med., Univ. of Kyoto, 2.Dept. of Neur., Grad. sch. of Med., Univ. of Kyoto)

ConBio2017

[1P-1211] Inhibition of the neuropathy target esterase (NTE) activity by organophosphates.

〇Naoko Abe¹, Masafumi Tanaka², Nami Motosugi², Masatoshi Itou³, Tomoichi Ohkubo³, Minoru Kimura² (1.Dept. of med., Grad. Sch. of med., Univ. of TOKAI, 2.Dept. of mol. sci., Div. of med., Univ. of TOKAI, 3.Sup. Cen., Ise. Res. Edu., Univ. of TOKAI)

ConBio2017

[1P-1212] Localization of ALS-linked SQSTM1 mutants in neuronal cells and effects of its expression on autophagy and cell viability

〇Ryohei Shirakawa¹, Masahisa Nozaki¹, Yutaro Hama¹, Kai Sato¹, Shun Mitsui¹, Suzuka Ono¹, Asako Otomo^1,2, Hui-Fang Shang³, Shinji Hadano¹ (1.Dept. of Mol.Life Sci., Med., Tokai Univ, 2.MNTC., Tokai Univ, 3.Dept. of Neurol., West China, Chengdu Univ., China)

ConBio2017

[1P-1213] Analysis of a new molecule that is involved in the PINK1-Parkin signaling.

〇Kahori Shiba¹, Tsuyoshi Inoshita¹, Yuko Aoki¹, Yashushi Ishihama², Yuzuru Imai³, Nobutaka Hattori¹ (1.Juntendo Univ. Department of Neurology, 2.Kyoto Univ. Department of Molecular and Cellular BioAnalysis, 3.Juntendo Univ. Department of Research for Parkinson's Disease)

ConBio2017

[1P-1214] The relationship between microtubule associated protein Tau and synaptic adhesion protein N-cadherin

〇Kyosuke Tanigawa¹, Megumi Asada^1,2,3, Kengo Uemura³, Ayae Kinoshita¹ (1.Dept. of Human Health Science., Grad. Sch. of Med., Kyoto Univ., 2.Shiga Univ. of Medical Science, 3.Clinical Neurology, Kyoto University Hospital)

ConBio2017

[1P-1215] Activation of mTORC1 signaling in cerebellar Purkinje cells causes cell death and hypertrophy of Purkinje cells.

〇Yusuke Sakai¹, Hidetoshi Kassai¹, Hisako Nakayama², Tatsuya Maeda³, Kazuki Nakao¹, Kouichi Hashimoto², Masanobu Kano⁴, Atsu Aiba¹ (1.Grad. Sch. Med., Univ. of Tokyo, 2.Grad. Sch. Biomed. Health Sci., Hiroshima Univ, 3.Inst. of Mol. Cel. Biosci., Univ. of Tokyo, 4.Dept. Neurophysiol., Grad. Sch. Med., Univ. of Tokyo)

ConBio2017

[1P-1216] Functional analysis of the crosstalk between the central nervous system and peripheral anti-tumor immune system via the activation of μ-opioid receptors in hypothalamic paraventricular nucleus

〇Yusuke Hamada¹, Naomi Kanao¹, Sara Yoshida¹, Michiko Narita¹, Hiroyuki Tezuka², Hideki Tamura², Masami Suzuki³, Kazunori Aoki⁴, Akihiro Yamanaka⁵, Naoko Kuzumaki¹, Minoru Narita^1,2 (1.Dept. Pharmacol., Hoshi Univ., 2.L-StaR, Hoshi Univ., 3.Div. Cancer Genomics, NCCRI, 4.Div. Mol. & Cell. Med., NCCRI, 5.Dept. Neurosci.II, RIEM, Nagoya Univ.)

ConBio2017

[1P-1217] The effect of neuronal cell-derived exosomes on microglial activation

〇Mutsumi Oshima¹, Takahiro Seki¹, Reiho Tsutsumi¹, Yuki Kurauchi¹, Akinori Hisatsune^2,3, Hiroshi Katsuki¹ (1.Dept. Chemico-Pharmacol. Sci., Grad. Sch. Pharm. Sci., Kumamoto Univ. , 2.Priority Organization for Innovation and Excellence, Kumamoto Univ., 3.Program for Leading Grad. Sch"HIGO Program", Kumamoto Univ.)

ConBio2017

[1P-1218] Solving the Mechanism of Rett syndrome

〇Shin-ichi Horike¹, Kenta Okumura², Gensaku Okada¹, Makiko Meguro¹ (1.Division of Functional Genomics, Advanced Science Research Center, Kanazawa University, 2.Medical Research Training Program, School of Medicine, Kanazawa University)

ConBio2017