[1P-1321] Analysis of factors that affect functional mechanisms and efficiency of Cas9 and dCas9 in CRIPSR/Cas9 system.

〇Shohei Maruyama¹, Daisuke Ichikawa², Qingbo Wang³, Yutian Li⁴, Kumiko Ui-Tei^1,2,3 (1.Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 3.Dept. of Bioinfo. and Syst. Biol., Sch. of Sci., Univ. of Tokyo, 4.Div. of Biol. Sci., UC San Diego)

ConBio2017

[1P-1322] Development of genome editing technology in sugi using CRISPR/Cas9 system

〇Mitsuru Nishiguchi¹, Norihiro Futamura¹, Yasunori Ohmiya^1,2, Masaki Endo³, Masafumi Mikami^3,4, Seiichi Toki^3,4,5, Ken-ichi Konagaya², Yoshihiko Nanasato², Toru Taniguchi², Tsuyoshi E. Maruyama¹ (1.FFPRI, 2.FBRC, FFPRI, 3.NIAS, NARO, 4.Grad. Sch. of Nanobio, Yokohama City Univ., 5.KIBR, Yokohama City Univ.)

ConBio2017

[1P-1323] Genetic rescue experiments in albino mice using GONAD method.

〇Shuji Takabayashi¹, Takuya Aoshima¹, Masahiro Sato², Masato Ohtsuka³ (1.Lab.Ani., Preemi.Med.Photo., Hama. Univ. Sch. of Med., 2.Sec. of Gene Exp. Regul, FSRC, Kagoshima Univ., 3.Dept. of Bas,Med., Sch. of Med., Tokai Univ.)

ConBio2017

[1P-1324] Genome editing of immune cells using CRISPR/Cas9 system

〇Tomona Yamaguchi¹, Tomoko Kawagoe¹, Takayuki Fujieda¹, Yoshitaka Koudo¹, Hirotaka Fukushima¹, Fuminori Kato¹, Kensei Kuroda¹, Yasufumi Kaneda² (1.Life Sci. Biz. Dev. HQ., ISHIHARA SANGYO KAISHA, LTD., 2.Div. of Gene Ther. Sci., Grad. Sch. of Med., Osaka Univ.)

ConBio2017

[1P-1325] Binding Affinity of Cas9 to DNA Determines Its HDR and NHEJ Activities

〇Tomoko Kato¹, Gou Takahashi¹, Szuyin Hsu¹, Yuichiro Miyaoka¹ (1.Tokyo Metropolitan Insitute Of Medical Science)

ConBio2017

[1P-1326] An atlas of association rules across mouse phenotypes

〇Nobuhiko Tanaka¹, Hiroshi Masuya¹ (1.Tech. and Dev. Unit for Knowl. Base of Mouse Pheno., RIKEN BRC)

ConBio2017

[1P-1327] Easy and highly-efficient delivery of cells to the bone marrow

〇Takahiro Kuchimaru¹, Tatsuhiro Isozaki¹, Hitomi Miyabara¹, Misa Minegishi¹, Tetsuya Kadonosono¹, Shinae Kondoh¹ (1.Sch. Life. Sci. and Tech. )

ConBio2017

[1P-1328] Production of genetically engineered rats using frozen-thawed pronucleus-stage embryos

〇Sho Motomura¹, Takao Tanaka¹, Yoshihiro Ooguti¹, Yuki Kanda¹, Hiromi Iwayama¹ (1.KAC Co.,LTD.)

ConBio2017

[1P-1329] Development and characterization of an RNA trans-splicing molecule targeting to cancer-type OATP1B3

〇Hideyuki Ide¹, Yuchen Sun¹, Manami Harada¹, Naohiko Anzai², Ulrich Koller³, Anna Stierschneider³, Josefina Piñón Hofbauer³, Christina Gruber³, Kan Chiba¹, Hidetaka Akita¹, Tomomi Furihata^1,2 (1.Lab. of Pharmacol. and Toxicol., Grad. Sch. of Pharmaceut. Sci., Chiba Univ., 2.Dept. of Pharmacol., Grad. Sch. of Med., Chiba Univ., 3.Lab. for Mol. Ther., EB-Hause Austria)

ConBio2017

[1P-1330] Epigenome editing: manipulating DNA methylation of specific DNA loci using CRISPR/Cas9 and a repeating peptide array-based amplification.

〇Sumiyo Morita¹, Hirofumi Noguchi², Takuro Horii¹, Kazuhiko Nakabayashi³, Mika Kimura¹, Kohji Okamura⁴, Atsuhiko Sakai², Hideyuki Nakashima², Kenichiro Hata³, Kinichi Nakashima², Izuho Hatada¹ (1.Biosignal Genome Resource Center, IMCR, Gunma University, 2.Stem Cell Biology and Medicine, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 3.Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, 4.Department of Systems BioMedicine, National Research Institute for Child Health and Development)

ConBio2017