[3P-0158（4LT01-02）] Novel mechanisms regulating the expression level of STK11/LKB1 by two ubiquitin ligases

〇Yusuke Takahashi¹, Yusuke Hirata¹, Takuya Noguchi¹, Atsushi Matsuzawa¹ (1.Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

ConBio2017

[3P-0159（4LT01-03）] Crystal structure of trimeric LUBAC reveals essential role of a novel HOIL-1L-SHARPIN interaction in LUBAC formation and function

〇Hiroaki Fujita¹, Akira Tokunaga², Masahiro Shirakawa², Kazuhiro Iwai¹ (1.Dept. of Mol. and Phys., Grad. Sch. of Med., Univ. of Kyoto, 2.Dept. of Mol. Eng., Grad. Sch. of Eng., Univ. of Kyoto)

ConBio2017

[3P-0160（4LT01-04）] Functional analysis of a novel RING-type ubiquitin ligase which controls LUBAC activity

〇Takanori Abe¹, Eiji Goto¹, Daisuke Oikawa¹, Hirotaka Takahashi², Takuro Horii³, Seigo Terawaki¹, Izuho Hatada³, Tatsuya Sawasaki², Huminori Tokunaga¹ (1.Dept. of Path., Grad. Sch. of Med., Osaka City Univ., 2.Proteo-Science Center, Ehime Univ., 3.Lab. of Genome Sci., Biol. Genome Resource Center, Inst. for Mol. and Cell. Reg., Gunma Univ.)

ConBio2017

[3P-0161（4LT01-07）] Lysosomal ubiquitin ligase RNF182 regulates mTORC1 signaling through recruitment of amino acid transporter LAT1 to lysosomes

〇Masayuki Kaneko¹, Xiao Peng Guo¹, Kazunori Imaizumi¹ (1.Dept. of Biochem., Inst. of Biomed. & Hlth. Sci., Hiroshima Univ.)

ConBio2017

[3P-0162（4P1T25-06）] The mechanism of Sentrin-specific protease 2 in substrate recognition and its role in TGF-beta induced tumorigenesis

Chia-Ju Lin¹, Tsai-Ling Ho¹, Hsin-Mei Liu¹, Ruei-Ting Chang¹, 〇Che-Chang Chang¹ (1.Graduate Institute of Translational Medicine, College of Medical Science and Technology, Taipei Medical University)

ConBio2017

[3P-0163（4P1T25-08）] Shedding susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation

〇Kyoko Shirakabe¹, Takuya Omura¹, Yoshio Shibagaki², Emiko Mihara³, Keiichi Homma⁴, Yukinari Kato⁵, Akihiko Yoshimura⁶, Yoshinori Murakami⁷, Junichi Takagi³, Seisuke Hattori², Yoshihiro Ogawa^1,8,9 (1.Dept. of Mol. End. & Metab., Grad. Sch. of Med. & Dent., TMDU, 2.Div. of Biochem., Sch. of Pharm., Kitasato Univ., 3.Lab. of Prot. Syn. & Exp., Inst. for Prot. Res., Osaka Univ., 4.Dept. of Life Sci. & Info., Maebashi Inst. of Tech. , 5.Dept. of Anti. Drug Dev., Grad. Sch. of Med., Tohoku Univ. , 6.Dept. of Micro. & Imm., Keio Univ. Sch. of Med. , 7.Div. of Mol. Path., IMSUT, 8.Dept. of Med. & Bioreg. Sci., Grad. Sch. of Med. Sci., Kyushu Univ. , 9.AMED, CREST)

ConBio2017

[3P-0164（4P1T25-09）] Post-translational palmitoylation regulates cancer cell proliferative signaling of CKAP4

〇Ryota Sada¹, Hirokazu Kimura¹, Katsumi Fumoto¹, Hideki Yamamoto¹, Akira Kikuchi¹ (1.Dept. of Mol. Biol., Biochem., Grad. Sch. of med., Univ. of Osaka)

ConBio2017

[3P-0165（4P1T25-11）] Effects of PRMT1 splice variants on biological functions

〇Hayase Mizukami¹, Jun-Dal Kim², Junji Ishida², Akiyoshi Fukamizu² (1.Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba, 2.Life Sci. Cent. of Tsukuba Adv. Res. Alliance, Univ. of Tsukuba)

ConBio2017

[3P-0166（4P1T25-12）] Age-related abnormal Asp 58 and Asp 151 residues in human lens water soluble aggregates

〇Takumi Takata¹, Noriko Fujii¹ (1.Dept. of Bio. Gerontol., Res. React. Ins., Kyoto Univ.)

ConBio2017

[3P-0167] Purification and functional analysis of PEGylated proteins using a novel structured PEG reagent

〇Chisato Yamada¹, Adam Wawro^2,3, Kimiko Kuroki¹, Ami Takahashi¹, Takahiro Muraoka^2,3, Kazushi Kinbara^2,3, Katsumi Maenaka¹ (1.Grad. Sch. Facul. of Pharm. Sci., Hokkaido Univ., 2.Grad. Sch. of Biosci. & Biotech., Tokyo Inst. of Tech., 3.Inst. of Multi. Res. Adv. Mater. (IMRAM), Tohoku Univ.)

ConBio2017