[2T04a-02（3P-043）] Adiponectin receptors contribute desaturation of phospholipids by their phospholipase A2 activity

^〇Yutaro Yagi¹, Hiroki Kawana¹, Kuniyuki Kano¹, Nozomu Kono¹, Hiroaki Tanabe², Miki Iwabu-Okada³, Masato Iwabu³, Toshimasa Yamauchi³, Takashi Kadowaki⁴, Shigeyuki Yokoyama², Junken Aoki¹ (1.Department of Health Chemistry, Graduate School of Pharmaceutical Science, The University of Tokyo, 2.RIKEN Cluster for Science, Technology & Innovation Hub, 3.Department of Diabetes & Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, 4.Toranomon hospital)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:30 PM - 1:40 PM

[2T04a-03（3P-045）] The PAQR family members are novel enzymes contributing to phospholipid metabolism.

^〇Hiroki Kawana¹, Hirofumi Onishi¹, Yutaro Yagi¹, Kuniyuki Kano¹, Nozomu Kono¹, Hiroaki Tanabe^2,3, Miki Okada-Iwabu⁴, Masato Iwabu⁴, Toshimasa Yamauchi⁴, Takashi Kadowaki⁵, Shigeyuki Yokoyama^2,3, Junken Aoki¹ (1.Dept. of Health Chem., Grad. Sch. of Pharm. Sci., The University of Tokyo, 2.RIKEN Baton Zone Program Yokoyama Lab, 3.RIKEN Clust. for Sci., Technol. & Innov. Hub, 4.Dept. of Diabetes & Metab. Dis., Grad. Sch. of Med., The University of Tokyo, 5.Toranomon hosp.)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:40 PM - 1:50 PM

[2T04a-04（2P-054）] Group III secreted phospholipase A₂ facilitates tissue infiltration of eosinophils by mobilizing lysophospholipid mediators

^〇Kyohei Horikiri^1,2, Yoshitaka Taketomi¹, Kenji Kondo², Tatsuya Yamasoba², Makoto Murakami^1,3 (1.CDBIM, Grad. Sch. of Med., UTokyo, 2.Dep. of Otolaryngology and Head and Neck Surgery, Grad. Sch. of Med., UTokyo Hospital, 3.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:50 PM - 2:00 PM

[2T04a-05（1P-059）] Lysophosphatidylglucoside affects macrophages via GPR55 and involves atherosclerosis.

^〇Ryosuke Shimai^1,2, Kei Hanafusa³, Hitoshi Nakayama^3,4,5, Masaki Kato⁶, Kouki Kano⁷, Ichiro Matsuo⁷, Yoshio Hirabayashi⁸, Kazuhisa Iwabuchi^3,4,5, Tetsuro Miyazaki², Takashi Tokano², Tohru Minamino¹ (1.Department of Cardiovascular Biology and Medicine, Juntendo University, Graduate School of Medicine, 2.Department of Cardiology, Juntendo Urayasu Hospital, 3.Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, 4.Laboratory of Biochemistry, Juntendo University Faculty of Health Care and Nursing, 5.Infection Control Nursing, Juntendo University Graduate School of Health Care and Nursing, 6.Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, 7.Graduated School of Science and Technology, Gunma University, 8.Neural Cell Dynamics, RIKEN Center for Brain Science)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:00 PM - 2:10 PM

[2T04a-06（1P-058）] LPA3 signaling alters breathing patterns through afferent vagal nerves

^〇Masaki Nakamura¹, Kuniyuki Kano¹, Junken Aoki¹ (Grad. Sch. of Pherm. Sci., Tokyo Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:10 PM - 2:20 PM

[2T04a-07（1P-054）] The group XIIA secreted phospholipase A₂ regulates Th17 cell differentiation leading to Th17 associated autoimmune diseases

^〇Chika Mochizuki¹, Yoshitaka Taketomi¹, Takahiro Nakajima², Yusuke Endo², Kuniyuki Kano³, Junken Aoki³, Makoto Murakami^1,4 (1.CDBIM, Grad. Sch. Med., UTokyo, 2.Lab. Med. Omics Res., Kazusa DNA Res. Inst, 3.Lab. Health Chem., Grad. Sch. Pharm. Sci., UTokyo, 4.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:20 PM - 2:30 PM

[2T04a-08（2P-067）] Hepatocyte-derived extracellular vesicles converge inflammation via lysophospholipids

^〇Shunya Nakayama^1,2, Yasushi Nakamoto¹, Kousuke Kamiya¹, Yoshimi Miki³, Yoshiki Shiraishi⁴, Yoko Ito⁴, Koichiro Asano⁴, Makoto Murakami³, Ai Kotani^1,5 (1.Dept. of Innov. Med. Sci. Tokai Univ., 2.Dept. of Hematology & Onclogy. Tokai Univ., 3.Lab. of Microenvironmental and Metab. Health Sci. Fac. of Med. Univ. Tokyo, 4.Dept. of Respir. Med. Tokai Univ., 5.Hematol. Malignancy. Inst. Med. Sci. Tokai Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:30 PM - 2:40 PM

[2T04a-09（1P-049）] Therapeutic effects of overexpression of lysophosphatidylcholine acyltransferase 4 (LPCAT4)/lysophospholipid acyltransferase 10 (LPLAT10) in the liver on glucose metabolism

^〇Kahori Shimizu¹, Moe Ono¹, Takenari Mikamoto¹, Yuya Urayama¹, Hiroki Nakanishi², Tomoyuki Terada¹, Fuminori Sakurai³, Hiroyuki Mizuguchi^3,4,5,6, Hideo Shindou^7,8, Koji Tomita¹, Toru Nishinaka¹ (1.Faculty of Pharmacy, Osaka Ohtani University, 2.Lipidome Lab Company, Limited., 3.Graduate School of Pharmaceutical Sciences, Osaka University, 4.National Institute of Biomedical Innovation, Health and Nutrition, 5.Global Center for Medical Engineering and Informatics, Osaka University, 6.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), 7.National Center for Global Health and Medicine, 8.Graduate School of Medicine, The University of Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 2:40 PM - 2:50 PM

[2T05a-01（1P-119）] Regulation of steroid 5α reductase by transcription factor

^〇JeongJu Ma¹, Goki Yamada¹, Tomoaki Hirakawa^2,3, Sudarma Bogahawaththa^2,3, Tomoaki Kawamura^2,3, Takashi Shimomura⁴, Tadayuki Tsujita^1,2,3 (1.Laboratory of Biochemistry, Department of Health Function Molecular Science, Faculty of Advanced Health science, Saga University, 2.Laboratory of Biochemistry, Department of Applied Biochemistry and Food Science, Faculty of Agriculture, Saga University, 3.The United Graduate School of Agricultural Sciences, Kagoshima University, 4.Dojindo Laboratories)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:20 PM - 1:30 PM

[2T05a-02（1P-115）] Molecular mechanism by which NADP (H) allosterically suppresses the affinity between ferredoxin:NADP+reductase and ferredoxin

^〇Yoko Kimata¹, Masayuki Miyata¹, Karen Fukuta¹, Rina Shinkoda¹, Yoshiro Nishimizu¹ (Graduate School of Sciences and Technology for Innovation, Yamaguchi University)

The 95th Annual Meeting of the Japanese Biochemical Society |Thu. Nov 10, 2022 1:30 PM - 1:40 PM