[1P-186（3T17m-06）] Screening of lysosome positioning mediated Autophagy Inducer using Image analysis, and application to Parkinson's disease treatment drug

^〇Yuki Date¹, yukiko sasazawa², Yasuyuki Kida³, Hideyuki Saya⁶, Eisuke Itakura⁴, Masaya Imoto⁷, Shinji Saiki⁵, Nobutaka Hattori⁵ (1.Department of Biology, Graduate school of Science and Engineering, Chiba University, 2.Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, 3.Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), 4.Department of Biology, Graduate school of Science, Chiba University, 5.Department of Neurology, Juntendo University School of Medicine, 6.Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine,, 7.Juntendo University Graduate School of Medicine)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-187（1T17m-05）] Cis-membrane association of human ATG8 proteins N-terminus mediates autophagy

^〇Taki Nishimura^1,2,3, Wenxin Zhang¹, Deepanshi Gahlot^4,5, Chieko Saito², Colin Davis⁶, Harold B J. Jefferies¹, Anne Schreiber⁶, Lipi Thukral^4,5, Sharon A. Tooze¹ (1.Mol Cell Biol of Autophagy Lab, The Francis Crick Institute, 2.Dep of Biochem Mol Biol, Grad Sch of Med, The Univ of Tokyo, 3.JST-PRESTO, 4.CSIR-Institute of Genomics and Integrative Biology, 5.AcSIR, CSIR-HRDC, 6.Cellular Degradation Systems Lab, The Francis Crick Institute)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-188] Analysis of hepatocyte apoptosis induction mechanism by Candida species

^〇Lin Maoyi¹, Maho Shirai¹, Xinyue Chen¹, Kanami Orihara¹, Susumu Kajiwara¹ (School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-189] Impact of external Hypoxia on blastocyst development and early implantation in pregnant mice

^〇Amma Asmaa Y.^1,2, Hossam H Shawki¹, Hisashi Oishi¹ (1.Department of Comparative and Experimental Medicine, Graduate school of Medical Sciences, Nagoya City University, 2.Animal Health Research Institute, Agriculture Research Center)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-190（2T18m-05）] Mechanism of nitric oxide-induced cell death via CHOP expression

^〇Kana Fujikawa¹, Nodoka Ito¹, Seiichi Oyadomari², Takashi Uehara¹ (1.Department of Medicinal Pharmacology, Grad. Sch. Med. Dent. & Pharma. Sci. Okayama University, 2.Institute of Advanced Medical Sciences, Tokushima University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-191] Isoliquiritigenin induces the accumulation of intracellular protein aggregates by inhibiting the proteasome and simultaneously suppresses survivin expression, causing to cell death in melanoma cells

^〇Akihisa Abe¹, Shota Moriya¹,Hiromi Kazama¹ (Department of Biochemistry, Tokyo Medical University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-192] The validation of generality of a "kick-me-out" signal, FGF21 in mammalian cell competition

^〇Mina Yano¹, Ogawa Motoyuki¹, Ichijo Hidenori¹ (Cell Signaling, Grad. Sch. Pharmaceut. Sci., Univ. of Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-193] Cell death mechanisms on cultured dish coated with titanium by sputtering

^〇Misuzu Tsunematsu¹, Hisashi Hisatomi¹ (Department of Materials and Life Science, Faculty of Science and Technology, Seikei University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-194（2T18m-08）] DNA damage response signaling induces cellular senescence by remodeling mitochondrial metabolism

^〇Shota Yamauchi¹, Hidenori Ichijo¹ (Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-195] Changes of mitogen-activated protein kinases (MAPKs) in the axotomized rat facial nucleus

^〇Ishijima Takashi¹, Nakajima Kazuyuki¹ (Glycan & Life Systems Integration Center (GaLSIC), Soka University)

The 95th Annual Meeting of the Japanese Biochemical Society