[1P-266（1T17e-02）] Genetic and life-style factors influencing plasma metabolic profiles in Japanese population

^〇Seizo Koshiba^1,2,3, Ikuko Motoike^1,4, Jin Inoue^1,2, Eiji Hishinuma^1,2, Yuichi Aoki^1,4, Miyuki Sakurai¹, Mitsuharu Sato¹, Kei Nanatani^1,2, Shu Tadaka^1,4, Matsuyuki Shirota^1,3,4, Kengo Kinoshita^1,2,4, Masayuki Yamamoto^1,2,3 (1.Tohoku Medical Megabank Organization (ToMMo), Tohoku University, 2.The Advanced Research Center for Innovations in Next-Generation Medicine (INGEM), Tohoku University, 3.Graduate School of Medicine, Tohoku University, 4.Graduate School of Information Sciences, Tohoku University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-267] Going library-free for protein identification using Zeno SWATH DIA and in silico-generated spectral libraries

^〇Takeshi Shibata¹, Ushio Takeda¹, Christie Hunter², Alexandra Antonoplis² (1.K.K. AB SCIEX, 2.SCIEX, USA)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-268（2T11a-09）] Milisecond dynamics of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM

^〇Sajidah Elma Sakinatus¹, Keesiang Lim², Tomoyoshi Yamano³, Takeshi Yoshida^2,3, Akiko Kobayashi⁴, Masaharu Hazawa^2,4, Yuka Inaba⁵, Hiroshi Inoue⁵, Rikinari Hanayama^2,3, Toshio Ando², Richard W. Wong^1,2,4 (1.Division of Nano Life Science in the Graduate School of Frontier Science Initiative, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 2.WPI-Nano Life Science Institute, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 3.Department of Immunology, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan, 4.Cell-Bionomics Research Unit, Institute for Frontier Science Initiative (INFINITI), Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan, 5.Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative (INFINITI), Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-269] Implementation of taste receptor proteins in taste sensors

^〇Manami Ushirosako¹, Miho Hashiba¹, Hiroyuki Oshikane² (1.Department of Clinical Laboratory, Faculty of Medical Technology, Teikyo University, 2.Graduate School of Pharmaceutical Sciences, Osaka University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-270（1T17e-07）] Development of NanoLuc-based indicator system to detect Coronavirus infections.

^〇Masashi Arakawa¹, Akiho Kashiwabara^2,3, Shinya Okamura^2,3, Hirotaka Ebina^2,3, Eiji Morita¹ (1.Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, 2.Virus vaccine group, BIKEN Innovative Vaccine Research Alliance Laboratories, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, 3.The Research Foundation for Microbial Diseases of Osaka University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-271（1T17e-06）] Development of method to analyze in vivo mechano-sensing of osteocyte using two-photon microscopy

^〇Hina Takegami¹, Takanobu Fukunaga², Masamichi Yamamoto³, Keizo Nishikawa¹ (1.Graduate School of Life and Medical Sciencies, Doshisha University, 2.Faculty of Engineering, Kyushu University, 3.National Cerebral and Cardiovascular Center Hospital)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-272] Bioluminescence imaging of differential secretory dynamics of bone-related proteins, osteocalcin and BMP2, in osteoblasts

^〇Shinji Fukuda¹, Honami Sugimoto^1,2, Satoru Yokawa³, Takuma Sato², Ken Miyazawa², Tadahide Furuno³, Shigemi Goto², Takahiro Suzuki¹ (1.Department of Biochemistry, School of Dentistry, Aichi Gakuin University, 2.Department of Orthodontics, School of Dentistry, Aichi Gakuin University, 3.Department of Analytical Chemistry and Biophysics, School of Dentistry, Aichi Gakuin University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-273] Feature extraction and system identification of human blood metabolome time series after glucose ingestion using tensor decomposition and model selection

^〇Suguru Fujita¹, Yasuaki Karasawa², Ken-ichi Hironaka¹, Y-h. Taguchi³, Shinya Kuroda¹ (1.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2.Department of Neurosurgery, Graduate School of Medicine, The University of Tokyo, 3.Department of Physics, Chuo University)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-274] Enhancement of insulin secretion by COA-Cl

^〇Ikuko Tsukamoto¹, Maki Takata¹, Akram Hossain¹, Wenhua Liu ², Katsuya Hirano¹, Fuminori Yamaguchi³, Junsuke Igarashi⁴, Masaaki Tokuda¹, Ryoji Konishi¹ (1.Fac. of Med., Kagawa Univ., 2.Shanghai Jiao Tong Univ. Sch. of Med., 3.Ehime Pref. Univ. of Health Sci., 4.Morinomiya Univ.of Med. Sci.)

The 95th Annual Meeting of the Japanese Biochemical Society

[1P-275] Effect of Sorghum (Sorghum bicolor) Extract or Apple Polyphenol on Adipogenic Differentiation of 3T3-L1 Preadipocyte

^〇Katsuyoshi Kamiie¹, Aozora Nagaoka¹, Makoto Sakurai¹, Atsuko Masumi² (1.Pharm. Sci., Aomori Univ., 2.Dept. Food Nutr., Human Life Sci., Miyagi Gakuin Women's Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society