[1P-244] Association of enzymatic activity with de novo missense mutations in ATP8B2, a phosphatidylcholine flippase

^〇Hiroyuki Takatsu¹, Alban Ziegler², Haruo Ogawa³, Kazuhisa Nakayama¹, Hye-Won Shin¹ (1.Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, 2.Department of Medical Genetics, Angers University Hospital, France, 3.Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kyoto University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-245] Enhancement of material production capacity by light energy supply for yeast expressing delta-rhodopsin in vacuolar membranes

^〇Kaoru Daicho¹, Yoko Hirono¹, Hiroshi Kikukawa¹, Kentaro Tamura¹, Kiyotaka Hara¹ (Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-246] Functional analysis of tight junction proteins CLDN14,16,19 from Homo sapiens

^〇Haruna Inamori¹, Satoshi Sano¹, Sumio Ishijima¹ (kyoto prefecture university)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-247(1T08a-07)] Integrin α5 mediates the adhesion of cancer cells to cancer-associated fibroblasts and contributes to invasion and peritoneal metastasis of scirrhous gastric carcinoma

Shingo Miyamoto¹, Yoshiko Nagano¹, Makoto Miyazaki¹, Yuko Nagamura¹, ^〇Hideki Yamaguchi¹ (Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-248(1T08a-06)] Cell adhesion receptors detect the unfolding pathway of their ligands

^〇Hiroaki Ogasawara¹, Rachel L. Bender¹, Anna V. Kellner², Hanna Grobe³, Arventh Velusamy¹, Aaron T. Blanchard⁴, Pere Roca-Cusachs^5,6,7, Ronen Zaidel-Bar³, Khalid Salaita^1,2 (1.Department of Chemistry, Emory University, 2.Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 3.Department of Cell and Developmental Biology, Tel Aviv University, 4.Department of Biomedical Engineering, Duke University, 5.Institute for Bioengineering of Catalonia (IBEC), 6.The Barcelona Institute for Science and Technology (BIST), 7.University of Barcelona)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-249] FilGAP, a GAP protein for Rac1, controls invadopodia formation in breast cancer cells

^〇Koji Saito¹, Sakino Ozawa¹, Yosuke Chiba¹, Ruri Takahashi¹, Ryoya Ogomori¹, Kojiro Mukai², Tomohiko Taguchi², Hiroyasu Hatakeyama³, Yasutaka Ohta¹ (1.Department of Biosciences, School of Science, Kitasato University, 2.Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, 3.Department of Physiology, School of Medicine, Kitasato University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-250(1T08a-05)] Molecular basis of promoting centriole microtubule triplet assembly by the ciliopathy protein HYLS1

^〇Yutaka Takeda¹, Takumi Chinen¹, Shunnosuke Honda¹, Sho Takatori², Shotaro Okuda¹, Taisuke Tomita², Shoji Hata¹, Daiju Kitagawa¹ (1.Laboratory of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-251] RhoGEFs, Solo and PDZ-RhoGEF cooperatively regulate actin cytoskeletal remodeling in mechanical stress responses

^〇Aoi Kunitomi¹, Syuhei Chiba¹, Atsushi Higashitani², Nahoko Higashitani², Kensaku Mizuno¹, Kazumasa Ohashi¹ (1.Mol. Cell. Biol., Grad. Sch. of Life Sci., Tohoku Univ., 2.Mol. Genet. and Physiol., Grad. Sch. of Life Sci., Tohoku Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-252] A RUN domain deletion mutant of Rufy4 promotes filopodia formation and suppresses osteoclast bone resorption

^〇Eiko Sakai¹, Yu Koyanagi¹, Fatima Farhana¹, Yu Yamaguchi¹, Takayuki Tsukuba¹ (Dept. Dental Pharmacol., Grad. Sch. Biomed. Sci., Nagasaki Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-253] Elucidation of the localization and function of s-Afadin in the mouse brain

^〇Rina Osada¹, Tomohiko Maruo^1,2, Kouki Maesaka¹, Kenji Mandai^1,2 (1.Department of Molecular and Cellular Neurobiology, Kitasato University Graduate School of Medical Sciences, 2.Department of Biochemistry, Kitasato University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society