[2P-215] Elucidation of tissue-specific metabolic mechanisms during chimeric antigen receptor T- cell therapy.

^〇Ari Itoh-Nakadai^1,2, Mariko Tomizawa-Murasawa¹, Hiroshi Kajita¹, Nahoko Suzuki¹, Yuriko Sorimachi³, Maiko Kobayashi², Takako Shimizu², Takehisa Matsumoto⁴, Mikako Shirouzu⁴, Keiyo Takubo³, Yoriko Saito¹, Fumihiko Ishikawa¹ (1.Laboratory for Human Disease Models, RIKEN Center for Integrative Medical Sciences, RIKEN, 2.Department of Hygiene and public Health, Graduate School of Medicine, Nippon Medical School,, 3.Department of Stem Cell Biology, Research Institute National Center for Global Health and Medicine, 4.Drug Discovery Structural Biology Platform Unit, RIKEN Program for Drug Development and Medical Technology Platforms, RIKEN)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-216] Mechanism of cell growth inhibition by novel glyoxalase 1 inhibitor

^〇Shuji Mori¹, Masahiro Watanabe¹, Hidenori Wake², Takashi Nishinaka², Omer Faruk Hatipoglu², Hideo Takahashi², masahiro Nishibori³, Takao Toyomura¹ (1.Sch Pharm, Shujitsu Univ, 2.Fac Med, Kindai Univ, 3.Okayama Univ, Grad Sch Med Dent Pharm Sci)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-217] Expression of butyrylcholinesterase and albumin by HuH-7 cells

^〇Yukiyo Hirata¹, Hirofumi Inagaki¹, Takako Shimizu¹, Yingji Li¹, Tomoyuki Kawada¹ (Nippon Med. Sch.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-218(1T04a-10)] Analysis of MITOL function in brown adipose

^〇Yuto Ishikawa¹, Ryuya Yokota¹, Isshin Shiiba¹, Eiki Takasaki¹, Fuya Yamaguchi¹, Shigeru Yanagi¹ (Gakushuin University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-219] Supersulfide catalysis for nitric oxide and aldehyde metabolism

^〇Masanobu Morita¹, Tetsuro Matsunaga¹, Shingo Kasamatsu², Md. Morshedul Alam³, Minkyung Jung¹, Seiryo Ogata¹, Uladzimir Barayeu¹, Tomoaki Ida¹, Motohiro Nishida⁴, Hozumi Motohashi³, Takaaki Akaike¹ (1.Dept. Environ. Med. Mol. Toxicol., Tohoku Univ., Grad. Sch. of Med., 2.Dept. of Bio Chem. Grad. Sch. of Sci., Osaka Metropolitan Univ., 3.Dept. Gene Exp. Reg., IDAC, 4.Grad. Sch. of Pharm. Sci. Kyushu Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-220] Kinetic analysis of the oxidation reaction mechanism of zinc finger proteins by H2O2

^〇Yuri Kawahito¹, Kanae Kishi², yuka Nakagawa³, Mami Hamori⁴, shigeru Negi¹ (1.Faculty of Pharmaceutical Sciences, Doshisha Womens College of Liberal Arts, 2.Graduate School of Biomedical and Health Sciences, Hiroshima University, 3.Graduate School of Faculty of Science, Hyogo University, 4.Faculty of Pharmaceutical Sciences, Kitasato University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-221] Breath Biopsy Technology Targeting for Ferroptosis-related Volatile Metabolites

^〇Yuta Matsuoka¹ (Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-222] Analysis of Membrane Oxidation in Cancer Cells with Knockdown of the Coenzyme Q Synthase Gene PDSS2

^〇Nene Wakamatsu¹, Yasuhiro Kudo¹, Akio Fujisawa¹, Tomoyasu Sugiyama¹, Ryuto Maruyama² (1.Tokyo University of Technology Graduate School of Bionics, Computer and Media Science Bionics Program, 2.Rikkyo University College of Science Department of Life Science)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-223] Supersulfides Omics Analysis in the Brain Tissue of the 5xFAD Mouse Model of Alzheimer's Disease

^〇Ayaka Kinno¹, Shingo Kasamatsu¹, Takaaki Akaike², Hideshi Ihara¹ (1.Dept. of Biol. Chem., Grad. Sch. of Sci., Osaka Metropolitan Univ., 2.Dept. of Environ. Med. Mol. Toxicol., Tohoku Univ. Grad Sch of Med.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-224(1T04a-09)] Analysis of impacts of cold exposure on intracellular supersulfur production in hibernating and non-hibernating animal cells

^〇Shingo Kasamatsu^1,2, Ryuto Toda², Takaaki Akaike³, Hideshi Ihara^1,2 (1.Dept. of Biol. Chem., Grad. Sch. of Sci., Osaka Metro. Univ., 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Pref. Univ., 3.Dept. of Environ. Med. Mol. Toxicol., Tohoku Univ. Grad Sch of Med.)

The 96th Annual Meeting of the Japanese Biochemical Society