[1T18a-06(1P-631)] Development of Novel SARS-CoV-2 Spike Binding Molecules using G-quadruplex based DNA Aptamer; IRDAptamer

^〇Masataka Mizunuma¹, Mirai Suzuki¹, Yuki Hara¹, Tamaki Kobayashi¹, Kazuhiro Furukawa², Yoshiro Chuman¹ (1.Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Niigata University, 2.Cell Regulation Laboratory in Biochemistry, Department of Chemistry, Faculty of Science, Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:25 PM - 2:34 PM

[1T18a-07(1P-634)] Drug discovery focused on regulation of NET release

^〇Madoka Ono¹, Masayasu Toyomoto^1,2,3, Momono Yamauchi¹, Masatoshi Hagiwara¹ (1.Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, 2.Department of Drug Discovery for Lung Diseases, Graduate School of Medicine, Kyoto University, 3.Department of Drug Discovery for Intractable Diseases, Graduate School of Medicine, Kyoto University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:34 PM - 2:43 PM

[1T18a-08(1P-642)] Development of bispecific T-cell Engager antibody based cyclic single-chain antibodies

^〇Mizuki Ogawa¹, Mana Namikawa², Shosei Kai², Yifan Yang¹, Rui Shi¹, Kyo Okazaki¹, Hitoshi Maeda³, Hiroshi Watanabe ³, Toru Maruyama³, Takashi Sato¹, Yoshihiro Kobashigawa¹, Hiroshi Morioka¹ (1.Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2.Department of Analytical and Biophysical Chemistry, School of Pharmacy, Kumamoto University, 3.Department of Analytical and Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:43 PM - 2:52 PM

[1T18a-09(2P-639)] Machine-learning-assisted molecular evolution for antibody fragment maturation

Tomoyuki Ito¹, Sakiya Kawada¹, Hikaru Nakazawa¹, Akikazu Murakami^2,3, ^〇Mitsuo Umetsu^1,4 (1.Graduate School of Engineering, Tohoku University, 2.Graduate School Biomedical Sciences, Tokushima University, 3.RePHAGEN Co. Ltd., 4.Advanced Intelligence Project , AIP)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:52 PM - 3:01 PM

[1T18a-10(2P-642)] Combined immunotherapy of chimeric antigen receptor T cells targeting STEAP1 with extracellular matrix-targeted IL-12 for advanced prostate cancer

^〇Koichi Sasaki¹, Bhatia Vipul², Ishihara Jun¹, Lee John K.^2,3,4,5 (1.Department of Bioengineering, Imperial College London, 2.Human Biology Division, Fred Hutchinson Cancer Center, 3.Division of Medical Oncology, University of Washington, 4.Department of Pathology and Laboratory Medicine, University of Washington, 5.Clinical Research Division, Fred Hutchinson Cancer Center)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:01 PM - 3:10 PM

[1T18a-11(1P-687)] Construction of VHH antibody display library using T7 phage and development of mirror image VHH antibody

^〇Kayu Maeda¹, Keisuke Aoki², Hiroaki Ohno², Jyoji Morise¹, Shogo Oka¹, Shinya Oishi³, Motohiro Nonaka¹ (1.Graduate School of Medicine, Kyoto University, 2.Graduate School of Pharmaceutical Sciences, Kyoto University, 3.Department of Medicinal Chemistry, Kyoto Pharmaceutical University )

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:10 PM - 3:19 PM

[1T18a-12(1P-640)] Conjugation of Synthetic TLR9 ligands to α-Mannose Immobilized Gold Nanoparticles for Enhanced Adjuvant Effects

^〇Koki Murata¹, Mayuko Shimoda², Mayumi Niimura², Masahiro Wakao¹, Yasuo Suda¹, Toshiro Moroishi^2,3, Hiroyuki Shinchi¹ (1.Graduate School of Science and Engineering., Kagoshima University, 2.Department of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, 3.Center for Metabolic Regulation of Healthy Aging, Faculty of Life Science, Kumamoto University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:19 PM - 3:30 PM

[1P-001] Rapid and simple ion-exchange fractionation for glycan sequencing

^〇Shigemitsu Segawa¹, Shunji Natsuka¹ (Graduate School of Science and Technology, Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-002] Detailed structural analysis of laminin N-linked glycans

^〇Juri Takahashi¹, Shunji Natsuka¹ (Graduate School of Science and Technology , Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-003] An easy and rapid preparation of labeled N-glycans for discovery of glycan biomarker to detect "unwellness"

^〇Riko Makino¹, Kousuke Morimura¹, Hend Zedan¹, Shunji Natsuka¹ (Grad. Schi. of Sci. & Tech., Niigata Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society