[3P-0335] A role of barrier-to-autointegration factor in DNA damage response

○Yuu Onoda¹, Namiko Noma¹, Ayumi Chikamatsu¹, Hiroki Iwamoto¹, Taro Mannen¹, Ryotaro Nishi², Toshiya Hayano¹ (1.Col. of Life Sci., Ritsumeikan Univ., 2.Sch. of Biosci. & Biotech., Tokyo Univ. of Technology,)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0336] Identification of polyphenols that repair DNA double strand break via SIRT6-dependent pathway

○Jun Kameyama¹, Saki Matsuoka¹, Yoshinori Katakura² (1.Grad. Sch. Biores. Bioenv. Sci., Kyushu Univ., 2.Fac. Agric., Kyushu Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0337] GABA (gamma-aminobutyric acid) Induces Intestinal Cells to Secrete Exosomes that Activate the Neuronal Cells.

○Mizuki Haraguchi¹, Ryo Inotsuka¹, Kanako Uchimura², Atsushi Yamatsu³, Mujo Kim³, Yoshinori Katakura⁴ (1.Grad.Sch.Biores.Bioenv.Sci.,Kyushu Univ., 2.Grad.Sch.Sys.Life Sci.,Kyushu Univ., 3.Pharma Foods International Co.,Ltd., 4.Fac.Agric.,Kyushu Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0338] Excess thiamine restored the short replicative lifespan of the acid phosphatase null mutant in yeast

○Toshio Nakajima¹, Yukio Mukai¹ (1.Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0339] Invention of compounds with specific growth inhibitory activity against T-cell acute lymphoblastic leukemia-derived cells

○Yuki Fujita^1,2, Tomoya Higashi^1,2, Yoshihumi Hachiro^1,2, Chihiro Yoshida^1,2, Chihiro Nakata^3,4, Takuya Yagi^3,4, Azusa Takechi^3,5, Nobuo Kitada^1,2, Rika Obata^1,2, Takahiko Hara^3,4,5, Shojiro Maki^1,2 (1. Dept. of Info. Sci., Grad. Sch., Univ. of Electro-Communications, 2. Center for Neuro Sci. and BioMed. Eng., Univ. of Electro-Communications, 3.Stem Cell Project., Tokyo Metropolitan Institute of Medical Science, 4.Dept. of Med. and Dent., Univ. of Tokyo Medical and Dental, 5.Dept. of Stem Cell reg., Univ. of Tokyo Metropolitan)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0340] Mint3 controls chemo-resistance of triple-negative breast cancer cells in tumor tissues

○Takeharu Sakamoto¹, Yuya Fukui¹, Hikari Okada², Shuichi Kaneko¹ (1.Dept. of System Biol., Inst. of Med., Pharm., Health Sci., Kanazawa Univ., 2.Dept. of Integ. Med. for Longevity, Grad. Sch. of Med. Sci., Kanazawa Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0341] Targeting all transforming growth factor-β isoforms with a novel Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer

○Hitomi Takahashi¹, Kazuki Takahashi¹, Yuichi Akatsu^2,3, Katarzyna A. Podyma-Inoue¹, Takehisa Matsumoto⁴, Yasuhiro Yoshimatsu^1,5, Daizo Koinuma², Mikako Shirouzu⁴, Kohei Miyazono², Tetsuro Watabe¹ (1.Dept. Biochem., Grad. Sch. Med. Dent., Tokyo Med. & Dent. Univ., 2.Dept. Mol. Pathol., Grad. Sch Med., Tokyo Univ., 3.Pharmaceutical Research Laboratories, Nippon Kayaku, 4.RIKEN, Biosystems Dynamic Research, 5.Div. Pharmacol., Grad. Sch. Med. Dent., Nigata Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0342] The gastrointestinal microbiota and clinical characteristics in patients with advanced solid tumor -SCRUM-Japan MONSTAR-SCREEN project-

○KENTARO SAWADA¹, Riu Yamashita², Satoshi Horasawa³, Shigenori Kadowaki⁴, Ken Kato⁵, Makoto Ueno⁶, Eiji Oki⁷, Naoki Takahashi⁸, Taro Sato⁹, Taito Esaki¹⁰, Daisuke Aoki¹¹, Kazuhiro Yoshida¹², Yoshiaki Nakamura^3,13, Hiroya Taniguchi^3,13, Takayuki Yoshino¹³ (1.Department of Oncology, Kushiro Rosai Hospital, Kushiro, 2.Translational Informatics, National Cancer Center Hospital East, 3.Translational Research Support Section, National Cancer Center Hospital East, 4.Department of Clinical Oncology, Aichi Cancer Center, 5.Department of Head and Neck Medical Oncology, National Cancer Center Hospital, 6.Hepatobiliary and Pancreatic Medical Oncology, Kanagawa Cancer Center, 7.Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 8.Department of Gastroenterology, Saitama Cancer Center, 9.Department of Frontier Science for Cancer and Chemotherapy, Graduate School of Medicine, Osaka University, 10.Gastrointestinal and Medical Oncology Division, National Hospital Organization Kyushu Cancer Center, 11.Department of Obstetrics & Gynecology, Keio University Hospital, 12.Department of Surgical Oncology, Gifu University Hospital, 13.Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0343] Anti-tumor activity of SRT1720 in adult T-cell leukemia/lymphoma

○Tomohiro Kozako¹, Naho Kato¹, Takeo Ohsugi², Akiyoshi Aikawa¹, Haruna Sato¹, Shinichiro Honda¹ (1.Dept. of Biochem, Fac. of Pharm., Fukuoka Univ., 2.Dept. of Lab. Animal Science, Sch of Vete Med, Rakuno Gakuen Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0344] Development of single nucleotide polymorphism-distinguishable siRNAs (SNPD-siRNAs) for KRAS mutations as anti-cancer drugs

○Atsushi Sato¹, Yoshiaki Kobayashi¹, Yoshimasa Asano¹, Kumiko Ui-Tei¹ (1.Depat. of. Biol.Sci., Grad, Sch, of Sci., Univ. of Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan