[3P-0365] Translational efficiency of mRNAs required for hematopoiesis were decreased in a zebrafish model of Diamond-Blackfan anemia

○Tamayo Uechi¹, Maki Yoshihama², Yukari Nakajima², Mariko Nagatomo², Yutaka Suzuki³, Naoya Kenmochi² (1.Fac. of Med., Univ. of Miyazaki, 2.Frontier Sci. Res. Ctr., Univ. of Miyazaki, 3.Grad. Sch. of Frontier Sci., Univ. of Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0366] A novel missense variant located within in GTP binding motif of GNAI3

○Kumiko Yanagi¹, Noriko Morimoto², Manami Iso³, Arisa Igarashi¹, Kazuhito Satou¹, Tadashi Kaname¹ (1.Dept. of Genome Med., NCCHD, 2.Div. of Otolaryngol., NCCHD, 3.Dept. of Pharmacol., NCCHD)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0367] New Therapeutic Approach Targeting Mitochondrial Energy Metabolism of Fibrodysplasia Ossificans Progressiva (FOP)

○Liping Sun^1,2, Yonghui Jin^1,2, Takeshi Kamakura^1,2, Sakura Tamaki^1,2, Junya Toguchida ^1,2,3,4 (1.Laboratory of Tissue Regeneration, Institute for Frontier Life and Medical Sciences, Kyoto University, 2.Laboratory of Differentiation Induction, Center for iPS Cell Research and Application, Kyoto University, 3.Institute for Advancement of a Clinical and Translation Science, Kyoto University Hospital, 4.Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0368] Screening of the rat hyperglycemic locus using Drosophila identified a transcription elongation factor CG8817(lilliputian) to be involved in carbohydrate metabolism

○ENLI LAN¹, Hiroyuki Kose¹ (1.International Christian University)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0369] A homozygous variant of NT5E affects Japanese patients with calcification of joints and arteries via loss of translation.

○Arisa Igarashi¹, Nana Kobayashi¹, Yukimi Abe¹, Makiko Omata¹, Kazuhito Sato¹, Shinsuke Kikuchi², Tetsuro Uchida³, Tsunehiro Shintani⁴, Kumiko Yanagi¹, Ryuji Higashita⁵, Atsushi Yamashita³, Ai Ishizawa³, Mitsuaki Sadahiro³, Nobuyoshi Azuma², Yoichi Matsubara⁷, Yoshio Makita⁶, Tadashi Kaname¹ (1.Dept. of Genome Med., NCCHD., 2.Dept. of Vascular Surgery, Univ. of Asahikawa Med., 3.Dept. of Surgery 2., Univ. of Yamagata, 4.Dept. of Vascular Surgery, Shizuoka Red Cross Hospital, 5.Dept. of Cardiovascular surgery, , 6.Education center, Univ. of Asahikawa Med., 7.Res. Inst., NCCHD)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0370] Deficiency and overexpression of Peg11/Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Ogata-Kagami syndromes

○Moe Kitazawa¹, Shinichiro Hayashi², Michihiro Imamura³, Shin'ichi Takeda³, Yumiko Oishi⁴, Tomoko Kaneko-Ishino⁵, Fumitoshi Ishino¹ (1.Dept.of Epigenetics, MRI, TMDU, 2.Dept. of Neuromuscular Res., NCNP, 3.Dept. of Mol. Thera., NCNP, 4.Dept. of Bioc. and Mol. Biol., Nippon Med. Sch., 5.Sch. of Med., Tokai Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0371] The MEK-ERK axis regulates conformational alteration in Cu/Zn-superoxide dismutase under zinc-deficient conditions

○Satoshi Takenaka¹, Takao Fujisawa¹, Atsushi Tsubota¹, Hidenori Ichijo¹ (1. Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0372] The novel cystic kidney gene Kansl1l forms cysts through the cilia

○Tomoko Kagiya¹, Shunji Itoh², Ikuji Hatamura² (1.Fac. of Medical tech., Dept. of Health Sci., Kansai Univ. of Health Sci., 2.Dept. of Health Sci., Grad. Sch., Kansai Univ. of Health Sci.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0373] RNA interference for causative genes of triplet repeat diseases by distinguishing the haplotypes of their single nucleotide polymorphisms

○Yuria Suzuki¹, Yoshiaki Kobayashi¹, Kumiko Ui-Tei¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0374] Single cell analysis to understand early stage of mouse psoriasis

○Shota Umemoto¹, Sadahiro Iwabuchi², Shinichi Hashimoto², Yasuhito Asano³, Hiroaki Yamamoto¹, Nobuo Nagai¹, Masaki Yoshida¹, Ryuhei Minei¹, Hiromasa Tabata¹, Atsushi Ogura¹ (1.Grad. Sci. of Bio., Inst. of Nagahama, 2.Mol. Pathol. A. of Res. Dept., Med. Univ. of Wakayama, 3.Info. Link. of UG., Univ. of Toyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan