The Molecular Biology Society of Japan

[1P-0376] A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair

○Kohei Nishimura1,2, Ryotaro Yamada3,5, Shinya Hagihara2,5, Rie Iwasaki3, Naoyuki Uchida3, Takumi Kamura2, Koji Takahashi2, Keiko U. Torii4, Tatsuo Fukagawa1 (1.Grad. Sch. of Frontier Biosci., Osaka univ., 2.Dev. of Biosci., Grad. Sch. of Sci., Nagoya univ. , 3.WPI-ITbM, Nagoya univ., 4.Dept. of Mol. Biosci., The Univ. of Texas at Austin, 5.RIKEN Center for Sustainable Resource Science)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0379] Establishment of exon-humanized mouse model for familial amyloidotic polyneuropathy optimal to develop a new therapy

○Seika Li1,2, Hideki Kanazashi3, Hironori Katoh3, Yoshimi Tokashiki3, Rie Fujikawa3, Ayaka Okagaki3, Sho Katoh3, Kenta Kojima3, Kyoko Haruna3, Naoko Matsusihita3, Haruko Kumamogoh3, Shingo Shinagawa3, Tomo-o Ishikawa3, Kenichi Yamamura2,3 (1.Dept. of Histol. Embryos., Harbin Med. Univ., 2.Institute of Resource Dev. and Analysis, Kumamoto Univ., 3.Transgenic, Inc.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0380] Studies on the fully human antibody-producing mice (1): Repertoire analysis of human immunoglobulin locus on the artificial chromosome in the mouse

○Hiroyuki Satofuka1, Takashi Moriwaki1,2, Satoshi Abe3, Hiroshi Tanaka3, Kayoko Morimoto3, Kyoutarou Yamazaki4, Kazuma Tomizuka5, Mitsuo Oshimura3, Yasuhiro Kazuki1,2 (1.CERC, Univ. of Tottori, 2.Dept. of Life Sci., Sch. of Med., Univ. of Tottori, 3.Trans Chromosomics Inc., 4.Dept. of Reg. Med. Biofunc., Grad. Sch. of Med. Sci., Univ. of Tottori, 5.Dept. of Life Sci., App. Life Sci., Tokyo Univ. of Pharm. Life Sci.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0381] Studies on the fully human antibody-producing mice (2): Analysis of antibody expression properties from human immunoglobulin genes in the mouse

○Takashi Moriwaki1,2, Hiroyuki Satofuka1, Satoshi Abe3, Hiroshi Tanaka3, kyoutarou Yamazaki4, Genki Hichiwa5, Kazuma Tomizuka6, Mitsuo Oshimura3, Yasuhiro Kazuki1,2 (1.CERC, Univ. of Tottori, 2.Dept. of Life Sci., Sch. of Med., Univ. of Tottori, 3.Trans Chromosomics Inc., 4.Dept. of Reg. Med. Biofunc., Grad. Sch. of Med. Sci., Univ. of Tottori, 5.Dept of Int. Med. Sci., Grad. Sch. of Med. Sci., Univ. of Tottori, 6.Dept. of Life Sci., App. Life Sci., Tokyo Univ. of Pharm. Life Sci.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0382] Studies on the fully human antibody-producing mice (3): Analysis of in vitro efficacy of fully human monoclonal antibodies against EpCAM

○Naomi Miyake1, Yasuyuki Satofuka2, Takasi Moriwaki1,2, Satoshi Abe5, Hiroshi Tanaka5, Kayoko Morimoto5, Kunitaro Yamazaki3, Genki Hichiwa4, Yayan Wang1, Mitsuo Oshimura5, Takeshi Fukuhara6, Yasuhiro Kazuki1,2,3 (1.Dept. of Life Sci., Sch. of Med., Univ. of Tottori, 2.CERC, Univ. of Tottori, 3.Dept. of Reg. Med. Biofunc., Grad. Sch. of Med. Sci., Univ. of Tottori, 4.Dept. of Gen and Cell, Med. sci, Univ. of Tottori, 5.Trans Chromosomics Inc., 6.Dept. of Neurlogy, Univ. of Juntendo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0383] Efficacy and safety of non-cytotoxic herpes simplex virus-based vectors in vivo

○Yoshitaka Miyagawa1, Motoyo Maruyama2,3, Atsushi Sakai2, Yuriko Sato1, Seiji Kuroda1, Hiromi Kinoh4, Motoko Yamamoto1, Ryotaro Hashizume5, Hidenori Suzuki2, Justus B. Cohen6, Joseph C. Glorioso6, Takashi Okada4 (1.Dept. of Biochem. Mole. Biol., NIPPON MED SCH, 2.Dept. of Pham., NIPPON MED SCH, 3.Dept. of Lab. Anim. Sci., NIPPON MED SCH, 4.Div. of Mole. Medi. Genet., Univ. of TOKYO, 5.Dept. of Path. Matrix, Biol., Univ. of Mie, 6.Dept. of MicroBiol. Mole. Genet., Univ. of Pit)

The 43rd Annual Meeting of the Molecular Biology Society of Japan