[3P-0345] Monoamine oxidase B inhibitor has anti-proliferative effect on Gemcitabine-resistant pancreatic cancer cells

○Kumiko Miyashita¹, Makoto Miyoshi¹, Kazuya Shimizu^1,2, Ken Sasai³, Tsuyoshi Akagi³, Yuichi Hori¹ (1.Dept. of Biophysics, Grad. Sch. of Health Sci., Univ. of Kobe, 2.Dept. of Internal Medicine, Kobe Med Center , 3.KAN Research Institute, Inc, Kobe, Japan)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0346] Discovery of new benzhydrol derivatives as potent and selective apoptosis inducers of human melanomas bearing the activated ERK pathway

○Ryosuke Satoh¹, Naoya Hamada¹, Fumihiro Ishikawa¹, Teruaki Takasaki¹, Genzoh Tanabe¹, Reiko Sugiura¹ (1.Fac. of Pharm., Kindai Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0347] Withdrawn

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0348] Distinct DNA methylation targets by chronic inflammation and aging

○Satoshi Yamashita¹, Sohachi Nanjo^1,2, Emil Rehnberg¹, Naoko Iida¹, Hideyuki Takeshima¹, Takayuki Ando², Takao Maekita³, Toshiro Sugiyama², Toshikazu Ushijima¹ (1.Div. Epigenomics, Nat. Cancer Cent. Res. Inst., 2.3rd Dep. Inter. Med., Univ. Toyama, 3.2nd Dep. Inter. Med., Wakayama Med. Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0349] Application to cancer immunotherapy with cancer antigens expressed using transgenic silkworms

○Kanae Yamada¹, Ken-ichiro Tatematsu³, Hideki Sezutsu³, Kazuaki Chikamatsu², Shigeki Takeda¹ (1.Faculty of Science and Technology, Univ. of Gunma, 2.Graduate School of Medicine, Univ. of Gunma, 3.Transgenic Silkworm Research Unit, NARO)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0350] Exploring Lung Cancer Evolution Under EGFR-TKIs Therapy Through Mathematical Modeling

○Qian Yu^1,2, Hiroshi Haeno³, Susumu Kobayashi^1,2,4 (1.Department of Integrate Biosciences, Graduate School of Frontier Science, The University of Tokyo, 2.Division of Translational Genomics, Group of Translational Research, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 3.Department of Computational Biology and Medical Sciences, Graduate School of Frontier Science, The University of Tokyo, 4.Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0351] Mechanism of cell death induced by MO2455 which disturbs poly (ADP-ribose) metabolism in gastric cancer NCI-N87 cells.

○Yuka Sasaki^1,2, Takae Onodera^1,2, Kenji Matsuno³, Takeji Takamura⁴, Fumiaki Koizumi^1,5, Mitsuko Masutani^1,2 (1.Dept. Molecular and Genomic Biomedicine, Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Lab. Collaborative Res., Div.Cell Signaling, Natl. Cancer Ctr. Res. Inst., 3.Faculty of Engineering, Kogakuin Univ., 4.Faculty of Engineering, Kanagawa inst. of tech., 5.Div. Clin. Res. Support, Komagome Hosp.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0352] Identification of modifier loci post-K-ras mutation by QTL analysis using K-rasG12V mediated lung tumor mouse models.

○Hiromitsu Saito¹, Noboru Suzuki¹ (1.Dept. Animal Functional Genomics, Advanced Sci. Res. Center, Mie Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0353] Development of liver-targeted drug delivery vehicle using hepatitis B virus-like particles

○Chiho Sakai¹, Kohei Hosokawa¹, Hirohumi Okawa¹, Tadashi Watanabe¹, Yuichi Sekine¹, Keiji Ueda², Masahiro Fujimuro¹ (1.Dept. of Cell Biol., Kyoto Pharm. Univ., 2.Dept. of Virol., Grad. Sch. of Med., Osaka Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0354] Investigation of anticancer effects and proapoptotic activity of ACA-28, a novel ERK signaling modulator, against cancer cells with high ERK

○Naoya Hamada¹, Ryosuke Satoh¹, Teruaki Takasaki¹, Genzoh Tanabe², Jun Adachi³, Takeshi Tomonaga³, Reiko Sugiura¹ (1.Lab. of Mol. Pharmacogenom., Fac. of Pharm., Kindai Univ., Japan, 2.Lab. of Organic Chem., Fac. of Pharm., Kindai Univ., Japan, 3.Laboratory of Proteome Research, National Institute of Biomedical Innovation, Health and Nutrition Japan)

The 43rd Annual Meeting of the Molecular Biology Society of Japan