^○Tatsuya Ohyama¹, Hisae Tateishi-Karimata¹, Shigenori Tanaka², Naoki Sugimoto^1,3 (1. FIBER, Konan Univ., 2. Grad. Sch. Sys. Inf., Kobe Univ., 3. FIRST, Konan Univ.)

[Lang.] English

Break (10:20 AM - 10:30 AM)

10:30 AM - 10:40 AM

[D1441-2am-09] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (83) :Bulge-containing G-quadruplexes is a new target motif to regulate gene expression in therapeutics

^○Sunipa Sarkar¹ (1. FIBER, Konan University)

[Lang.] English

10:40 AM - 10:50 AM

[D1441-2am-10] Development of a dual-site-recognition type telomeric G4 ligand with photo-cross-linking group

^○Kazuki Yanagita¹, Shogo Sasaki¹, Yue Ma², Kazunori Ikebukuro¹, Takatsugu Hirokawa³, Masayuki Tera¹, Kazuo Nagasawa¹ (1. Tokyo University of Agriculture and Technology, 2. Tokyo Medical and Dental University, 3. Division of Biomedical Science, University of Tsukuba))

[Lang.] Japanese

10:50 AM - 11:00 AM

[D1441-2am-11] Improved DNA Recognition Through Invasion Complex Formation Using Multiple Pairs of Parallel-Type PNAs

^○Naoya Mochizuki¹, Masanari Shibata¹, Yuichiro Aiba¹, Kota Ito¹, Shinya Ariyasu¹, Osami Shoji¹ (1. Nagoya University)

[Lang.] Japanese

11:00 AM - 11:10 AM

[D1441-2am-12] Synthesis of chemical probes for the analysis of the dynamic forming behavior of G- quadruplexes

^○Haruki Fujita¹, Naruyuki Watatani¹, Syogo Sasaki¹, Yue Ma², Masayuki Tera¹, Kazuo Nagasawa¹ (1. Tokyo University of Agriculture and Technology, 2. Tokyo Medical and Dental University)

[Lang.] Japanese

11:10 AM - 11:20 AM

[D1441-2am-13] Analysis of Liquid-liquid phase separation inducing ability with macrocyclic hexaoxazole-type G-quadruplex ligands

^○Akari Oyama¹, Shogo Sasaki¹, Masayuki Tera¹, Kazuo Nagasawa¹ (1. Tokyo University of Agriculture and Technology)

[Lang.] Japanese

11:20 AM - 11:30 AM

[D1441-2am-14] Development of G-quadruplex forming sequence predictor and application to the SARS-CoV-2 genome sequences.

^○Rena Nohara¹, Junya Kitamura¹, Hiina Seino¹, Shogo Sasaki¹, Akira Shiraishi², Kazunori Ikebukuro¹, Masayuki Tera¹ (1. Tokyo University of Agriculture and Technology, 2. Suntory Foundation for Life Sciences)

[Lang.] Japanese

11:30 AM - 11:40 AM

[D1441-2am-15] Elucidation of mechanism and function of TERRA aggregates

^○keishi deguchi¹, tatsuki masuzawa², kentaro takahama¹, Ayako Okushima¹, riki kurokawa³, Takanori Oyoshi^2,1,4 (1. Graduate school of integrated Science and Technology, Shizuoka University, 2. Graduate School of Science and Technology, Shizuoka University, 3. Research Center for Genomic Medicine, Saitama Medical University, 4. Research Institute of Green Science and Technology, Shizuoka University)

[Lang.] Japanese

Session information

[D1441-2am] 17. Biofunctional Chemistry, Biotechnology

[D1441-2am-01] The Effects of Loop Region on G-quadruplex Folding Mechanism

[D1441-2am-02] Interaction and photo-induced electron transfer between DNAs and a cationic phthalocyanine derivative

[D1441-2am-03] Photo-decomposition of G-quadruplex DNAs with anionic Zn(Ⅱ) phthalocyanine

[D1441-2am-04] Serendipitous discovery of E. coli-like microrod formation by self-assembly of DNA-β-sheet peptide conjugates

[D1441-2am-05] Unique triplex structure formed by acyclic nucleic acid

[D1441-2am-06] Effects of DNA sequences and cosolutes on the formation of hexagonal DNA assemblies

[D1441-2am-07] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (84) : Fluorescence light-up through binding of dye molecules to specific loop sequences of i-motif DNA

[D1441-2am-08] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (85): Investigation of accumulation mechanism for RNA G-quadruplexes with G₄C₂ repeats and poly-dipeptides

[D1441-2am-09] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (83) :Bulge-containing G-quadruplexes is a new target motif to regulate gene expression in therapeutics

[D1441-2am-10] Development of a dual-site-recognition type telomeric G4 ligand with photo-cross-linking group

[D1441-2am-11] Improved DNA Recognition Through Invasion Complex Formation Using Multiple Pairs of Parallel-Type PNAs

[D1441-2am-12] Synthesis of chemical probes for the analysis of the dynamic forming behavior of G- quadruplexes

[D1441-2am-13] Analysis of Liquid-liquid phase separation inducing ability with macrocyclic hexaoxazole-type G-quadruplex ligands

[D1441-2am-14] Development of G-quadruplex forming sequence predictor and application to the SARS-CoV-2 genome sequences.

[D1441-2am-15] Elucidation of mechanism and function of TERRA aggregates

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