[2P-371] Transforming growth factor-β1 induces MMP-10-mediated invasion of HSC-4 human squamous cell carcinoma cells

^○Hino Masafumi^1,2, Saito Daishi¹, Kyakumoto Seiko², Cyosa Naoyuki², Ibi Miho^2,3, Yoshida Mariko², Mizuki Harumi¹, Ishisaki Akira², Kamo Masaharu² (1.Div. of Oral and Maxill. Surg., Dept. of Reconst. Oral and Maxill. Suge., Iwate. Med. Univ, 2.Div. of Cell. Bio. Sci., Dept. of Biochem., Iwate. Med. Univ, 3.Div. of Tumor Biol., Inst. Biomed. Sci., Iwate. Med. Univ)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-372] BIM _EL is a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine

^○Tanaka Yukie¹, Komatsu Takayuki², Shigemi Hiroko³, Fujii Yutaka¹ (1.Dept. of Mol. Bio. and Chem., Facul. of Med. Sci., Univ. of Fukui, 2.Dept. of Microbiol. and Immunol., Sch. of Med., Aichi Med. Univ., 3.Dept. of Hem. and Onco., Facul. of Med. Sci., Univ. of Fukui)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-373] Natural source material suppresses microbiological product induced carcinogenesis by inhibitionof MAPK kinase signaling pathway

^○Tokuda Harukuni, Xu Fenghao, Suzuki Nobutaka (Kanazawa Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-374] Luteolin regulates angiogenesis of chorioallantoic membranes and NF-kB activity of vascular endothelial cells

^○Ashino Hiromi^1,2, Ono Tomio², Takiguchi Masaki¹ (1.Dep.of Biochem.Genetics, Chiba Univ.Grad.Sch.of Med., 2.Lab. of Transgenic Technol., Tokyo Metropol.Inst.of Med.Sci.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-375] Disease-associated EED Ile363Met mutation increases susceptibility to hematologic malignancies

^○Ueda Takeshi¹, Nagamachi Akiko², Nakata Yuichiro¹, Yamasaki Norimasa¹, Matsui Hirotaka², Honda Hiroaki¹ (1.Dept. of Disease Model, Res. Inst. Rad. Biol. Med., Hiroshima Univ., 2.Dept. of Mol. Oncol., Res. Inst. Rad. Biol. Med., Hiroshima Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-376] (2T15a-13)A somatic mutation of mitochondrial DNA confers resistance against an anti-cancer drug.

^○Amo Taku^1,2, Miyamoto Tetsuya², Kamimura Naomi², Asano Hiromasa¹, Asoh Sadamitsu², Ohta Shigeo² (1.Dept. of Appl. Chem., Natl. Defense Acad., 2.Dept. Biochem. & Cell. Biol., Inst. Dev. Aging Sci., Grad. Sch. Med., Nippon Med. Sch.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-377] The role of TGF-β signaling in extracellular microRNA secretion and cell-to-cell transfer

^○Katsura Akihiro¹, Suzuki Hiroshi^1,2, Sugimoto Koichi³, Miyazono Kohei¹ (1.Dev. of Molecular Pathology, Graduate School of Med., Univ. of Tokyo, 2.David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 3.Department of Hematology and Oncology, JR Tokyo General Hospital)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-378] Positive and negative regulation of Wnt target genes by p63 (TP63)

^○Kurata Shun-ichi¹, Fukunishi Nahoko¹, Fujimuro Masahiro², Katoh Iyoko³ (1.Med. Res. Inst., Tokyo Med. and Dent. Univ., 2.Cell Biol., Kyoto Pharmaceut. Univ.Cent. Med. Edu. Sci., Faculty of Med., Univ. of Yamanashi, 3.Cent. for Med. Edu. & Sci., Faculty of Med., Univ. of Yamanashi)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-379] Mechanism of DNA damage and apoptosis induced by pirarubicin, an anthracycline antitumour agent.

^○Mizutani Hideki¹, Hotta Saki¹, Nishimoto Ayano¹, Hiraku Yusuke², Kawanishi Shosuke³ (1.Coll. Pharm., Kinjo Gakuin Univ., 2.Dept. Environ. Mol. Med., Mie Univ. Grad. Sch. Med., 3.Fac. Pharm. Sci., Suzuka Univ. Med. Sci.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-380] (2T15a-15)Metabolomic analysis of pancreas cancer by capillary electrophoresis-mass spectrometry (CE-MS)

^○Hirayama Akiyosi¹, Mikata Rintaro², Soga Tomoyoshi¹ (1.1) Inst. Adv. Biosci., Keio Univ., 2.Grad. Sch. Med., Chiba Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM