The Japanese Biochemical Society

[2P-466] Lipid-peroxidation stress induces oligomeization and insolubilization of alpha-synuclein, and modulate proteolysis system in SH-SY5Y cells

Shamoto-Nagai Masayo1, Hisaka Shinsuke2, Osawa Toshihiko3, Naoi Makoto3, Motoyama Noboru1, Manamiyama Makoto1, Maruyama Wakako1 (1.Dep. of Cognitive Brain Sci., NCGG, 2.Dept. of Pharmacognosy, Fac. of Pharm., Meijo Univ., 3.Dept. of Hlth. and Nutr. Fac. of Psycological & Physical Sci., Aichi Gakuin Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-467] Amyloid β-protein (1-42, O-acyl isopeptide form) is an inherently monomeric equivalent of an aggregative amyloid β-protein (1-42)

Yoshiya Taku1, Maruno Takahiro2, Uemura Tsuyoshi1, Kubo Shigeru1, Kiso Yoshiaki3, Sohma Youhei4, Yoshizawa-Kumagaye Kumiko1, Kobayashi Yuji2, Nishiuchi Yuji1,5 (1.Peptide Institute, Inc., 2.Grad. Sch. of Eng., Osaka Univ., 3.Dept. of Bio-Sci., Nagahama Inst. of Bio-Sci. and Tech., 4.Grad. Sch. of Pharm. Sci., The Univ. of Tokyo, 5.Grad. Sch. of Sci., Osaka Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM