[1P-496_1SP-06-19] Improvement of ligand compounds for an orphan GPCR highly expressed in brain

^○Hijiri Yoshida¹, Hiroyuki Hirano², Hiroyuki Osada^2,3, Shigeki Takeda¹ (1.Graduate school of Science and Technology, Gunma University, 2.RIKEN center for Sustainable Resource Science, 3.Department of Pharmaceutical Sciences, University of Shizuoka)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-497] Mechanisms of epithelial cell proliferation and differentiation in mouse vagina through epithelial–stromal tissue interaction

^○Tatsuki Goto¹, Eriko Senoo¹, Sho Yamazaki¹, Genki Yamagishi¹, Moeka Sakaguchi², Kenji Toyota^1,3, Shinichi Miyagawa¹ (1.Dept. of Biol. Sci. and Tech., Grad. Sch. of Adv. Eng., Tokyo Univ. of Sci., 2.Dept. of Biol. Sci. and Tech., Fac. of Adv. Eng., Tokyo Univ. of Sci., 3.Noto Marine Lab., Inst. of Nature and Env. Tech., Kanazawa Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-498_1SP-06-15] Gprc5a is a gene induced by PTH that functions as a repressor of BMP signaling and suppresses the proliferation and differentiation in osteoblasts.

^○Chisato Sampei¹, Kosuke Kato¹, Yasuhiro Arasaki¹, Yuta Kimura¹, Takuto Konno¹, Kanon Otsuka¹, Masaki Noda^2,3, Yoichi Ezura^2,4,5, Yukihiro Kohara¹, Tadayoshi Hayata^1,2 (1.Dept. of Mol. Pharmacol., Grad. Sch. of Pharm. Sci., Tokyo Univ. of Sci., 2.Dept. of Mol. Pharmacol., Med. Res. Inst., TMDU, 3.Ctr. for Stem Cell and Regen. Med., TMDU, 4.Dept. of Jt. Surgery and Sports Med., Grad. Sch. of Med. and Dent. Sci., TMDU, 5.Dept. of Occup. Ther., Fac. of Health and Med. Sci., Teikyo Heisei Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-499] GM1 Ganglioside Protects Against LPS-Induced Neuroinflammatory and Oxidative Responses by Inhibiting the Activation of Akt, TAK1 and NADPH Oxidase in MG6 Microglial Cells

^○YuanShieh Huang¹, TingYin Yeh² (1.Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, 2.Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-500_1SP-06-17] Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts.

^○Yuka Maejima², Kayo Machihara¹, Takushi Namba^1,2 (1.Res. And Educ. Fac., Multidiscip. Sci. Clus., Interdiscip. Sci. Unit, Univ. of Kochi, 2.Dept. of Mar. Res. Sci., Fac. of Agr and Mar Sci., Univ. of Kochi)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-501] CsA prolongs the anagen phase by suppressing not only TGF-β2 but also FGF5 expression

^○Kenta Hagiwara, Yuka Tsuchiya, Hiroaki Kitamura, Tokuro Iwabuchi (Tokyo University of Technology)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-502] Hypoxic response of the expression of hair cycle-regulating genes in human hair follicle cells

^○Shogo Ueno¹, Marin Sugano¹, Haruyo Yamanishi^1,2, Sera Goto¹, Tokuro Iwabuchi¹ (1.Faculty of Bioscience and Biotechnology, Tokyo University of Technology, 2.Department of Anatomy, Kawasaki Medical School)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-503] Inhibitory effect of dihydrocolletodiol produced by the fungus Halosphaeriaceae sp. isolated from the brown alga on LPS/IFNγ co-stimulated NO production in murine macrophage RAW264.7 cells.

^○Tomoka Sakai¹, Takeshi Yamada², Tomohiro Itoh¹ (1.Dept, of Life Sci., Grad. Sch. of Bioresour., Mie Univ., 2.Dept. of Pharma. Sci., Osaka Med. Pharm. Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-504] Latanoprost promotes phagocytosis of melanin by follicular epithelial cells

^○HIKARI TAKAHASHI¹, Yuuki Tsunekawa¹, Keita Kogoshi¹, Hitoshi Masaki², Tokuro Iwabuchi¹ (1.Dept. of Biosci. Biotec., Univ of Tokyo univ of technology, 2.Research institute for human health science, Konan University)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-505] Immunophilin ligands suppress FGF18 expression through CDK4 upregulation, promoting the transition to the growth phase.

^○Tomoki Shioji, Kenta Hagiwara, Kitamura Hiroaki, Tokuro Iwabuchi (Dept. of Biosci. Biotec., Univ of Tokyo univ of tecnology)

The 46th Annual Meeting of the Molecular Biology Society of Japan