[2P-069] Positive role of p130RB2 in ATR activation in response to replication stress

^○Chiharu Uchida¹, Hiroyuki Niida², Bunsyo Shiotani³, Masatoshi Kitagawa² (1.Hamamatsu Univ. Sch. Med., PMPERC, ARFS, 2.Hamamatsu Univ. Sch. Med., Dept. Mol. Biol., 3.Natl. Cancer Ctr. Res. Inst.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-070] Investigating of DNA replication speed regulating factors

^○Shojyu Endo^1,3, Taichi Igarashi^2,3, Megumi kato^1,3, Kimiyoshi Yano³, Bunsyo Shiotani³ (1.Dept. of NCC Cancer Sci., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ., 2.Dept. of Bio. Sci., Grad. Sch. of Sci., Kitasato Univ., 3.Lab. of Gen. Stress Signal., Natl. Cancer Ctr. Res. Inst.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-071] Elucidation of mechanism underlying DNA replication-mediated Osimertinib resistance

^○Megumi Kato^2,1, Kimiyoshi Yano², Syoju Endo^2,1, Taichi Igarashi^2,4, Yoshihisa Kobayashi³, Bunsyo Shiotani² (1.Dept. of NCC Cancer Sci., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ., 2.Lab. of Genome Stress Signal., Natl. Cancer Ctr. Research Inst., 3.Div. Mol. Pathology, Natl. Cancer Ctr. Research Inst., 4.Dept. of Bio. Sci., Grad. Sch. of Sci., Kitasato Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-072] Mechanism of maintaining ribosomal RNA gene stability by Swd1, a component of the histone methyltransferase complex

^○Yumika Yagi^1,2, Takehiko Kobayashi^2,1, Shuichi Yanagi² (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2.IQB, Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-073] A common mechanism and architecture of the dynamic nucleoprotein complex formed at the origin DNA of eubacterial chromosome replication

^○Shogo Ozaki, Chuyuan Lu, Ryusei Yoshida, Yasutaka Wakasugi, Shohei Sato, Tsutomu Katayama (Dept. of Mol. Biol., Grad. Sch. of Pharm.Sci., Kyushu Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-074] Discovery of Novel Replication Proteins for Large Plasmids in Cyanobacteria and Their Potential Applications in Genetic Engineering.

^○Kazuma Ohdate¹, Minori Sakata¹, Kaisei Maeda², Yutaka Sakamaki¹, Kaori NimuraMatsune¹, Ryudo Ohbayashi³, Satoru Watanabe¹ (1.Dept. Biosci., Tokyo Univ. Agric., 2.IIR, Tokyo Inst. Technol., 3.Dept. Sci., Shizuoka Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-075] G-quadruplex in Myc-induced replication stress; as a potential therapeutic target

^○Takayuki Sekimoto (IMCR, Gunma Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-076] Regulation of Claspin by phosphorylation of its N-terminal segment.

^○Zhiying You, ChiChun Yang, Hisao Masai (Genome Dynamics, Dept. of Basic Med. Sci., Tokyo Metro. Inst. Med. Sci.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-077] Oligomerization of Rif1 is essential for its ability to suppresses replication over a long distance in S. pombe.

^○Yutaka Kanoh, Kaho Takasawa, Seiji Matsumoto, Hisao Masai (Genome Dynamics Project, Dept. Basic Med. Sci., Tokyo Metropolitan Inst. Med. Sci.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-078] Control of genome integrity by removal of PCNA from chromatin

^○Yasushi Shiomi¹, Yuki Shimizu¹, Kazushi Matsubara¹, Yuki Iwai¹, Masato Kanemaki^2,3, Hideo Nishitani¹ (1.Grad. Sch. of Sci., Univ. of Hyogo, 2.NIG, 3.Grad. Sch. of Sci., Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan