[2P-079] The accumulation mechanism of CRL4-Cdt2 ubiquitin ligase at the DNA replication sites by live imaging analysis

^○Tatsuya Bekki, Kei Ebihara, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani (Grad. Sch. of Sci., Univ. of Hyogo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-080_1PS-03-06] Knockout of Cdc7 or ASK (Dbf4) mice causes common and distinct phenotypes in a tissue-specific manner.

^○Tomohiro Iguchi¹, Karin Hori¹, Satoshi Yamazaki¹, Rie Ishii², Hiroyuki Sasanuma¹, Hisao Masai¹ (1.Dept. Basic Med. Sci., Genomic Dynamics Project, Tokyo Metropolitan Inst. Med. Sci., 2.Cent. For Basic Tech. Res., Lab. For Transgenic Tech., Tokyo Metropolitan Inst. Med. Sci.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-081] Galectin-3 regulates drug sensitivity by reducing PRIM1 mediated DNA damage response

^○DaBin Choi¹, HyeonGu Kang¹, SeokJun Kim^1,2,3 (1.Dept. of Int. Biol. Sci. & BK21 FOUR Edu. Res. Grou. for. Age-asso. Diso. Cont. Tech, Univ. of. Chosun, 2.Inst. of Well-Aging Medicare, Univ. of. Chosun, 3.Dept. of Biomed. Sci., Univ. of. Chosun)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-082_2AS-06-01] Mutagenesis mechanism of a formamidopyrimidine derivative produced by the active metabolite of food contaminant acrylamide

^○Junichi Akagi¹, Masayuki Yokoi², Yumi Miyake³, Tsuyoshi Shirai⁴, Tomohiro Baba⁵, YoungMan Cho¹, Fumio Hanaoka^6,2, Kaoru Sugasawa², Shigenori Iwai⁵, Kumiko Ogawa¹ (1.Div. of Pathology, Natl. Inst. of Health Sciences, 2.Biosignal Res. Ctr., Kobe Univ., 3.Forefront Res. Ctr., Grad. Sch. of Sci., Osaka Univ., 4.Dept. of Bioscience, Nagahama Inst. of Bio-Sci. and Tech., 5.Grad. Sch. of Eng. Sci., Osaka Univ., 6.Natl. Inst. of Genetics)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-083] Contribution of NHEJ and TMEJ to repair of DNA lesions induced by phleomycin D1 in plants

^○Ryouhei Yoshihara¹, Minako Toda¹, Miyo Ozu¹, Satoshi Kitamura², Hanako Shibata¹, Yuzuki Shimakura¹, Shin Hatakeyama¹, Shuuitsu Tanaka¹ (1.Grad. Sch. of Sci. & Eng. Saitama Univ., 2.Dept. Quantum-Appl. Biosci., QST)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-084] Crosstalk between Claspin, a replication checkpoint mediator, and various cellular signaling pathways ensures cellular responses to diverse biological stresses

^○ChiChun Yang, HaoWen Hsiao, Hisao Masai (Dept. Basic Med. Sci., Genomic Dynamics Project, Tokyo Metropolitan Inst. Med. Sci.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-085] Therapeutic genome editing using adeno-associated virus (AAV) for GJB2-related hearing loss

^○Takao Ukaji¹, Ryoya Nakagawa², Nureki Osamu², Kamiya Kazusaku¹ (1.Dept. of Oto., Sch. of Med., Juntendo Univ., 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-086] Construction of a gene disruption system using CRISPR-Cas9 in Halomonas sp. A020

^○Mei Hirata, Yoshinao Azuma (Dept. of Biotec. Sci., Grad. Sch. of Biol. Sci. Tec., Univ. of Kindai)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-087] Development and use of monoclonal antibodies against I-motif DNA structures

^○Cristian Pena Martinez, Daniel Christ (Kinghorn Cancer Centre, Garvan Institute, Univ. of New South Wales)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-088] Analysis of RFWD3-mediated DNA damage tolerance pathway in human cells

^○Rie Kanao^1,2, Yuji Masuda^1,2, Chikahide Masutani^1,2 (1.Res. Inst. Environ. Med., Nagoya Univ., 2.Nagoya Univ. Grad. Sch. Med.)

The 46th Annual Meeting of the Molecular Biology Society of Japan