[2P-482] Discovery of sequence motif independent specificity of kinase phosphorylation substrates

^○Takumi Sekiguti, Satoshi Fukuchi (Dept.of Life.Sci & Info.,Grad.Sch. of.Tec.,Maebashi Ins.of Tec.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-483] Elucidating the mechanism for the transition of population activity during the sleep-wake cycle by multi-modal data from multi-electrode array and epi-flourescence microscopy

^○Fukuaki Kinoshita^1,4, Katsuhiko Matsumoto², Rikuhiro Yamada³, Hiroki Ueda^2,4,3 (1.Dept. of Med. Grad. Sch. Osaka Univ, 2.Univ. of Tokyo, 3.Osaka Univ, 4.BDR. Riken)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-484_2AS-08-02] Human interleukin-1 receptor-associated kinase 1, a component of TLR/IL-1R pathway, involves the IL-1-mediated activation of Wnt/β-catenin pathway via its human-specific motif.

^○Hiroki Hikasa¹, Yasuhiro Mimura¹, Masako Inui¹, Kohei Otsubo², Masanori Taira³ (1.Dept. of Biochem., Sch. of Med., UEOH, 2.Dept. of Respi., Grad. Sch. of Med. Sci., Kyusyu univ., 3.Dept. of Sci., Inst. of Sci. and Engn., CHUO univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-485_2AS-16-03] Development of a new method for identifying ubiquitin-binding proteins based on the Split-TurboID technology

^○Marsya Nurrachma¹, Beni Lestari¹, Masayuki Komada^1,2, Toshiaki Fukushima^1,2 (1.Sch. of Life Sci. and Tech., Tokyo Tech., 2.Inst. of Innov. Res., Tokyo Tech.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-486] Identification of cell senescence-associated DUBs by profiling with activity-based ubiquitin probe

^○Nanami Kuramochi¹, Masayuki Komada^2,1, Toshiaki Fukushima^1,2 (1.Sch. of Life Sci. and Tech., Tokyo Tech, 2.Inst. of Innov. Res., Tokyo Tech)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-487] Protein co-variation network analysis aimed at analyzing stratified cellular responses

^○Rina Kunishige¹, Yoshiyuki Noguchi², Nobuhiko Maiya³, Daiki Nakatsu¹, Masayuki Murata^1,2 (1.Cell Biol. Cent., Inst. Innov. Res., Tokyo Inst. Tech., 2.IRCN., Inst. Adv. Study., Univ. of Tokyo, 3.Nikon Corp.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-488] Acquisition of castration resistance mediated by 3-O-sulfated heparan sulfate in prostate cancer.

^○Hayato Ota¹, Hirokazu Sato², Shuji Mizumoto³, Ken Wakai⁴, Kei Yoneda⁴, Kazuo Yamamoto⁴, Hayao Nakanishi⁵, JunIchiro Ikeda⁴, Shinichi Sakamoto⁴, Tomohiko Ichikawa⁴, Shuhei Yamada³, Satoru Satoru Takahashi⁶, Yuzuru Ikehara⁴, Shoko Nishihara^1,2,7 (1.Fac. of Sci. Eng., Soka Univ., 2.Grad. Sch. of Eng., Soka Univ., 3.Fac. of Pharm., Meijo Univ., 4.Grad. Sch. of Med., Chiba Univ., 5.Aichi Cancer Center, 6.Grad. Sch. of Med., Nagoya City Univ., 7.GaLSIC, Soka Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-489] Loss of Letmd1 in BAT promotes symptom of type 2 diabetes due to effect of high calorie diet or aging

^○Moeka Mukae, Kang ju Jeong, Narim Kim, Jinhee Lee, EuiJu Hong (Dept. of Biochem. Vet., Grad. Sch. of Vet., Univ. of Chugnam)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-490] Progesterone receptor membrane component 1 promote hepatic fibrosis via increasing Tgf-β reception in hepatic stellate cells

^○Moeka Mukae, Kang ju Jeong, Jinhee Lee, Narim Kim, EuiJu Hong (Dept. of Biochem. Vet., Grad. Sch. of Vet., Univ. of Chugnam)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-491] Anti-inflammatory effects of 3-hydro-2,2,5,6-tetramethylpyrazine in mice with contact dermatitis

^○Madoka Sawai¹, Yutaka Tatano¹, Shunji Itoh², Masaki Yoshida³, Zhou JianRong⁴, Yuu Miyauchi⁴, Shinji Takechi⁴ (1.Sch. Pharm., at Fukuoka. Int. Univ. Health & Welfare., 2.Dept. Health Sci., Grad. Sch. Health Sci., Kansai Univ. Health Sci., 3.Sch. Biosci. Biotech., TUT., 4.Fac. Pharmaceut. Sci., Sojo Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan