[2P-908_2SP-08-13] The effect of E50K Optineurin expression on lysosome-related organelles in retinal cells

^○Mayuna Obayashi¹, Wataru Otsu¹, Hideshi Tsusaki¹, Masamitsu Shimazawa^1,2 (1.Dept. of Biomed. Res. Lab., Gifu Pharm. Univ., 2.Mol. Pharmacol., Dept. of Biofunct. Eval., Gifu Pharm. Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-909] Exploring disease-specific methylation changes in hypogonadotropic hypogonadism

^○Erina Suzuki¹, Mami Miyado¹, Keiko Matsubara^3,1,2, Yoko Kuroki^4,3,2, Sayaka Kawashima¹, Kaori Hara¹, Kazuhiko Nakabayashi⁵, Saki Aoto⁶, Masayo Kagami¹, Tsutomu Ogata⁷, Maki Fukami¹ (1.Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2.National Research Institute for Child Health and Development, Division of Collaborative Research, 3.Division of Diversity Research, National Research Institute for Child Health and Development, 4.Department of Genome Medicine, National Research Institute for Child Health and Development, 5.Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, 6.Medical Genome Center, National Center for Child Health and Development, 7.Department of Pediatrics, Hamamatsu University School of Medicine)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-910_2SP-08-12] RNF213 and RBP-1 interactions modulate signaling pathways in endothelial cells

^○JUNGMI CHOI, Shohab Youssefian (Dept. of Mol. Sci., Grad. Sch. of Med., Univ. of Kyoto)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-911] Comparative analysis of causative genes for genetic rare diseases with different age of onset

^○Takuya Sakuratani (Dept. of Life Sci., Grad. Sch. of Life Sci., Univ. of Ritsumei)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-912] Regulatory mechanism for expression of ZEB2, the causative gene of Mowat-Wilson syndrome

^○Yasuyo Suzuki, Noriko Nomura, Kenichiro Yamada, Shin Hayashi (Dept. of Genet., Inst. for Develop. Res., Aichi Develop. Disability Ctr.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-913] Diverse genome-wide analyses in CdLS and CHOPS syndrome reveal common defects of enhancer organization mediated by cohesin

^○Toyonori Sakata^1,2, Shoin Tei¹, Kosuke Izumi³, Masashige Bando¹, Katsuhiko Shirahige^1,2 (1.IQB, The univ. of Tokyo, 2.Karolinska Institutet, 3.The Children's Hosp. of Philadelphia)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-914] Efficient preparation of adeno-associated virus vectors and their introduction into the retina

^○Naoya Shikada¹, Naoya Shigesada¹, Toru Kondo², Takuma Shinozuka¹, Noriaki Sasai¹ (1.Dev. Biomed. Sci., Nara Inst. Sci. Tech., 2.IGM,Hokkaido Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-915] Analysis of novel Emerin-interacting proteins

^○Daisuke Sato, Hiroaki Nakmura, Takako Abe, Taro Mannen, Toshiya Hayano (Ritsumeikan Univ., Col. of Life Sci.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-916] Functional analysis of Emerin mediated by Prohibitin/Prohibitin2

^○Seiya Shirasu, Ryo Igarashi, Takako Abe, Taro Mannen, Nobuyuki Shimohata, Toshiya Hayano (Col. of Life Sci., Univ. of Ritsumeikan)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-917] Rapid generation of transgenic mouse by iGONAD mimicking variant of uncertain significance (VUS) in genetic disorders clarifies its pathogenicity

^○Shin Hayashi¹, Yasuyo Suzuki¹, Daisuke Fukushi¹, Kenichiro Yamada¹, Hiroaki Miyahara² (1.Dept. Genet., Inst. Develop. Res., Aichi Develop. Disability Ctr., 2.Dept.Neuropathol., Inst. Med. Sci. Aging, Aichi Med. Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan