[2P-0440] Alteration of TDP-43 autoregulation-relevant splicing by DNA methylation status of TARDBP DNA

〇Yuka Koike¹, Akihiro Sugai¹, Akio Yokoseki¹, Tomohiko Ishihara¹, Norikazu Hara², Junko Ito³, Takeshi Ikeuchi², Akiyoshi Kakita³, Osamu Onodera¹ (1.Dept. of Neurol., BRI, Univ. of Niigata, 2.Dept. of Mol.Genet., BRI, Univ. of Niigata, 3.Dept. of Pathol., BRI, Univ. of Niigata)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0441(2AW-06-7)] CHCHD2 mutations cause TDP-43/TBPH misdistribution and exacerbate mitochondrial dysfunction

〇Hongrui Meng¹, Tsuyoshi Inoshita², Kahori Shiba-Fukushima², Kenya Nishioka⁴, Manabu Funayama³, Yuzuru Imai^4,5, Nobutaka Hattori^1,2,3,4 (1.Dept Neurodegenerative and Demented Disorders, Juntendo Univ. Tokyo, 2.Dept Treatment and Rsearch in Multiple Sceroses and Neuro-intractable Disease, Juntendo Univ. Tokyo, 3.Research Institute for Diseases of Old Age, Juntendo Univ. Tokyo, 4.Department of Neurology, Juntendo Univ. Tokyo, 5.Department of Research for Parkinson's Disease, Juntendo Univ. Tokyo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0442] Development of novel Drosophila model for Charcot-Marie-Tooth disease targeted to the SCO2 gene

〇Ryosuke Kowada¹, Kojiro Suda¹, Hideki Yoshida¹, Masamitsu Yamaguchi¹ (1.Dept. of Appli. Biol.,Insti. of Kyoto )

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0443] Drosophila model as therapeutic target for mitochondrial disease

〇Md Saheb Ali¹, Kojiro Suda¹, Hideki Yoshioda¹, Masamitsu Yamaguchi¹ (1.Department of Applied Biology, Kyoto Institute of Technology)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0444] Identification of epigenetic regulator gene Rpd3 which genetically interacts with CMT causingf gene FIG4

〇Yuuka Muraoka¹, Hideki yoshida¹, Masamitsu Yamaguchi¹ (1.Dept. of Appli. Biol., Kyoto Inst. of Technol)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0445] Elucidation of axonal transport and axonal degeneration association

〇Itsuki Yamamoto¹, Takayuki Shimoda², Takara Kitanishi¹, Shinichi Yonekura^1,2,3 (1.Graduate School of Science and Technology, Shinshu university, 2.Faculty of Agriculture, Shinshu university, 3.Institute for Biomedical Science, Shinshu University)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0446] Characterization of pathological mutations in IP3 receptor type I and CA8 identified in hereditary ataxia

〇Hideaki Ando^1,2, Matsumi Hirose^1,3, Katsuhiko Mikoshiba^1,4 (1.Lab. for Dev. Neurobiol., CBS, RIKEN, 2.Lab. of Mol. Biomed. for Pathog., Facul. of Med., Univ. of Tokyo, 3.Collab. Res. Resources, Sch. of Med, Keio Univ., 4.SIAIS, ShanghaiTech Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0447] Functional analyses of the genetically engineered mice for the neuropathy target esterase gene

〇Minoru Kimura¹, Naoko Abe², Nami Motosugi³, Kou Sakabe³, Akira Kato³ (1.Institute of Medical Sciences, Tokai University, 2.Graduate School of Medicine, Tokai University, 3.School of Medicine, Tokai University)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0448] Ninjurin1 mediates regeneration of peripheral nerve through Schwann cell maturation of NG2positive neural precursor cells

〇Yui Tomita^1,2, Kiwamu Horiuchi^1,3, Kohei Kano^1,3, Yuri Yoshida^1,4, Takamitsu Tatsukawa^1,4, Keiichi Nakajima¹, Taiki Hayasaka^1,3, Maki Kabara¹, Naoki Nakagawa³, Naofumi Takehara³, Naoyuki Hasebe^1,3, Jun-ichi Kawabe^1,5 (1.Dept. of Cardiovascular Regeneration and Innovation, Asahikawa Medical Univ., 2.Dept. of Radiology, Asahikawa Medical Univ., 3.Dept. of Medicine, Division of Cardiovascular, Respiratory and Neurology, Asahikawa Medical Univ., 4.Dept. of Vascular Surgery, Asahikawa Medical Univ., 5.Dept. of biochemistry, Asahikawa Medical Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0449(4W-20-2)] Polarization of reactive astrocytes in response to spinal cord injury is induced by M2 macrophage mediated activation of Wnt/β-catenin pathway

〇iki sonn¹, Masaya Nakamura¹, Hideyuki Okano¹, Francois Renault-Mihara¹ (1.Dept. of Physiol., Grad. Sch. of Med., Univ. of Keio)

The 42nd Annual Meeting of the Molecular Biology Society of Japan