[4P-0547] Identification of PRPF19 as a promising target for pancreatic cancer therapy

〇Shisei Kan¹, Kimiyoshi Yano^2,3, Ryou-u Takahashi¹, Hidetoshi Tahara¹ (1.Dept. of Cell. & Mol. Biol., Grad. Sch. of Biomed. & Health Sci., Univ. of Hiroshima, 2.Dept. of Cell. & Mol. Biol., Grad. Sch. of Biomed. & Health Sci., Univ. of Hiroshima, 3.JSPS Research Fellow (DC1))

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0548] Cell line selective cell death induction by combination of angiogenesis inhibitor TNP-470 and various anticancer agents

〇Naoto Kawagoe¹, Shunji Izuta¹ (1.FAST., Kumamoto Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0549(1PW-13-8)] Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor

Kenichi Iwai^1,2,7, Tadahiro Nambu¹, Ryo Dairiki¹, Momoko Ohori¹, JIe Yu², Krissy Burke², Masamitsu Gotou³, Yukiko Yamamoto¹, Shunsuke Ebara¹, Sachio Shibata¹, Ryosuke Hibino¹, Satoru Nishizawa¹, Tohru Miyazaki¹, Misaki Homma¹, Yuya Oguro¹, Takashi Imada¹, Nobuo Cho¹, Noriko Uchiyama⁴, Akifumi Kogame⁵, Toshiyuki Takeuchi⁵, Osamu Kurasawa¹, Kazunori Yamanaka³, Huifeng Niu⁶, 〇Akihiro Ohashi^1,2,7 (1.Onc. DDU, Takeda Pharmaceutical Company Limited, 2.Onc. DDU, Takeda Pharmaceuticals International Co., 3.InteRL Lab., Takeda Pharmaceutical Company Limited, 4.Biomol. Res. Lab., Takeda Pharmaceutical Company Limited, 5.DMPK Res. Lab., Takeda Pharmaceutical Company Limited, 6.Translational & Biomarker Res., Takeda Pharmaceuticals International Co., 7.Div. Translational Genomics, EPOC, National Cancer Center)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0550] Construction of correlation network for elucidation of metabolic control mechanism in Saccharomyces cerevisiae

〇Kazuki Yamasaki¹, Masaharu Maruyama¹, Syunsuke Nishino¹, Nobuyuki Okahashi¹, Hiroshi Shimizu¹, Fumio Matsuda¹ (1.Grad. Sch.IST., Univ. of Osaka)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0551] Zebrafish gut microbiome: a new resource for drug discovery.

〇Yasuhito Shimada^1,2,3, Fumiyoshi Okazaki^2,3,4, Liqing Zang^2,5, Hiroko Nakayama^2,5, Takanobu Mitani⁶, Harutaka Sakioki⁶, Shu-ping Hui⁷, Norihiro Nishimura^2,5 (1.Dept. of Pharmacol., Mie Univ. Grad. Sch. Med., 2.Mie Univ. Zebrafish. Screen. Cent., 3.Dept. Bioinfo., Mie Univ. Ad. Sci. Res, 4.Dept. of life Sci., Mie Univ. Grad. Sch. of Bio., 5.Mie Univ. Grad. Sch, Regional Innov., 6.Mie Univ. Sch Med., 7.Hokkaido Univ. Grad. Sch, Facul Health Sci.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0552] Environmental adaptation analysis of E. coli mutator colonized in murine intestine.

〇Tomoya Tsukimi^1,2, Suguru Shigemori³, Kazuharu Arakawa^1,2,4, Takahiro Masuda^1,2, Eiji Miyauchi⁵, Kenji Nakahigashi⁶, Masaru Tomota^1,2,4, Hiroshi Ohno^5,8, Hirotada Mori⁷, Shinji Fukuda^1,2,8,9,10 (1.Ins. for Adv. Biosci., Keio Univ., 2.Grad. Sch. of Med. and Gov., Keio Univ., 3.Ins. for Biomed. Sci, Shinsyu Univ., 4.Dept. of Env. and Info., Keio Univ., 5.IMS., RIKEN, 6.Spiber Inc., 7.Div. of Biol. Sci., NAIST, 8.KISTEC, 9.Metabologenomics, Inc., 10.Transbo. Med. Res. Cen., Tsukuba Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0553] Investigation of the obesity onset via gut microbiota in androgen receptor knockout mice

〇Haruno Takahashi^1,2, Kazuki Tanaka^1,3,4, Nao Takeuchi^1,3, Nozomu Obana⁵, Masaru Tomita^1,2,3, Shinji Fukuda^1,3,4,5,6 (1.Inst. Adv. Biosci., Keio Univ., 2.Environment & Info. Studies, Keio Univ., 3.Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 4.Intestinal Microbiota Project, KISTEC-KAST, 5.Transborder Medical Research Center, Univ. of Tsukuba, 6.Metabologenomics, Inc.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0554] Functional Analysis of ASK3 in Acetaminophen Induced Liver Failure (AILF)

〇Masako Sekiguchi¹, Isao Naguro¹, Hidenori Ichijo¹ (1.Dept. of Pham. Sci., Grad. Sch. of Pham., Univ. of Tokyo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0555] Modulation of PXR target genes by vitamin K in humanized PXR mice

Kimika Watanabe¹, Halima Sultana¹, Michiya Nishikido¹, Yusuke Ohsaki¹, Michio Komai¹, 〇Hitoshi Shirakawa¹ (1.Lab. Nutrition, Grad. Sch. of Agri. Sci., Tohoku Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0556] The changes in the glucose metabolic pathway under low oxygen and low glucose conditions

〇Akihito Miyata¹, Rika Sakuma¹, Susumu Imaoka¹ (1.Dept. of Biomed. Chem., Sch. of Sci. and Tech., Kwansei Gakuin Univ. of Hyogo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan