[4P-0588] The effect of IBD risk molecule LRRK2 on the DSS colitis in mice

〇Yuta Ishikawa¹, Fumitaka Kawakami¹, Rei Kawashima¹, Tatsunori Maekawa¹, Takafumi Ichikawa¹ (1.Dept. of Reg. Biochem. Grad. Sch. of Med. Sci., Kitasato Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0589] Elucidation of rhinitis suppression mechanism by Shinʹi

〇Takashi Sugihira¹, Seiji Mizutani¹, Tsuyoshi Ishii¹, Kazutake Fukada¹ (1.Rohto Pharmaceutical Co.,Ltd)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0590] Activation of NLRP3 infrasomes is important for placental inflammation induced by palmitic acid

〇Sayaka Shimazaki¹, Michiya Sano¹, Kumiko Tani¹, Yasuaki Kaneko¹, Tadayoshi Karasawa², Masahumi Takahashi², Hisataka Iwata¹, Takehito Kuwayama¹, Koumei Shirasuna¹ (1.Lab of Anim Reprod, Dep of Anim Sci, Tokyo Univ of Agr, 2.Div of Inflammation Research, Jichi Med Univ)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0591] Anti-connective tissue growth factor (CTGF) monoclonal antibody reduces skin fibrosis in mice models of systemic sclerosis

〇Katsunari Makino¹, Maria Trojanowska², Hironobu Ihn¹ (1.Dept. of Derm. and Plas., Kumamoto Univ., 2.Arthritis cent., Boston Univ. Sch. of Med.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0592] Metalloprotease Nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity

〇Mikiko Ohno¹, Hiroshi Matsuura², Kiyoto Nishi³, Takeru Makiyama⁴, Yasuhiko Kojitani⁴, Hirotaka Iwasaki¹, Shintaro Matsuda⁴, Eiichiro Nishi¹ (1.Dept. Pharma., Grad.Sch. of Med.,SUMS, 2.Dept. Physiol., Grad.Sch. of Med.,SUMS, 3.Dept. Anesthe., Grad.Sch. of Med.,Washington, U.S.A, 4.Dept. Cardiovasc., Grad.Sch. of Med.,Kyoto U.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0593] Biochemical characterization and molecular engineering of the minimal Cas9 from Campylobacter jejuni

〇Ryoya Nakagawa¹, Hiroshi Nishimasu¹, Osamu Nureki¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0594] Effect of surrounding environment of target cytosine in photochemical C to U transition using reversible RNA photo-cross-linking

〇Masaharu Nakano¹, Siddhant Sethi¹, Nozomi Honda¹, Shigetaka Nakamura¹, Kenzo Fujimoto¹ (1.Japan Advanced Institute of Science and Technology, School of Advanced Science and Technology)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0595] Double Nicking mediated precise point mutation in Dictyostelium

〇Hoshie Iriki¹, Ryoya Sekine¹, Tetsuya Muramoto¹ (1.Dept. of Biol., Grad. Sch. of Sci., Toho Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0596] Selection and characterization of aptamers against fibroblast growth factor (FGF) 5

〇Minami Saso¹, Ryo Amano¹, Masato Namekata², Masataka Horiuchi³, Takuya Yanagisawa¹, Kakeru Nishimoto¹, Yoichiro Tanaka⁴, Farhana Ishrat Ghani², Masakuni Yamamoto², Taiichi Sakamoto¹ (1.Chiba Inst. Tech., Dept. Life Env., 2.Advangen Inc., 3.Health Sci. Univ. Hokkaido, Fac. Pharm., 4.Yokohama Natl. Univ., Inst. Anal. Center)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0597] Characterization of aptamers that bind to the Vif - CBFβ - CUL 5 - ELOB - ELOC complex

〇Kazuyuki Kumagai¹, Takuya Suzuki¹, Yuta Sekigami¹, Keisuke Kanba¹, Li Wan², Kayoko Nagata³, Akifumi Takaori-Kondo³, Masato Katahira^2,4, Takashi Nagata^2,4, Taiichi Sakamoto¹ (1.Chiba Inst. Tech., 2.Inst. Adv. Energy, Kyoto Univ., 3.Dept. of Hematol./Oncol., Grad. Sch. of Med., Kyoto Univ., 4.Fund. Energy Sci. Dept., Grad. Sch. of Energy Sci., Kyoto Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan