[3P-0430] Effects of neonatal exposure to an anesthetic midazolam on neural stem/progenitor cell behavior in the adult mouse hippocampus

〇Hiroyoshi Doi^1,2, Taito Matsuda¹, Ken Yamaura², Kinichi Nakashima¹ (1.Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2.Department of Anesthesiology and Critical Care Medicine, Graduate school of Medical Sciences, Kyushu University)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0431] Elucidation of molecular mechanisms underlying NSC property change induced by prenatal VPA exposure

〇Shuzo Matsubara¹, Taito Matsuda¹, Hiroyoshi Doi¹, Atsuhiko Sakai¹, Kinichi Nakashima¹ (1.Dept. of Stem Cell Biol. Sci., Grad. Sch. of Med., Univ. of Kyushu)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0432] Mechanisms of maldigestion/malabsorption, hypoglycemia and death induced by glial calcineurin deficiency

〇Masahiko Tanaka¹, Umi Okura¹, Naohide Hirashima¹ (1.Dept. of Cell. Biophys., Grad. Sch. of Pharmaceut. Sci., Nagoya City Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0433(3PW-06-6)] Dopaminergic neurodegeneration triggered by exosomes derived from activated microglia.

〇Takahiro Seki¹, Yuria Hori¹, Reiho Tsutsumi¹, Yuki Kurauchi¹, Hiroshi Katsuki¹ (1.Dept. of Chemico-Pharmacol. Sci., Grad. Sch. Pharm. Sci., Kumamoto Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0434] Brain vascular endothelial cell senescence-initiated SASP-triggered activation of microglia

〇 Machiko Morimoto¹, Sayo Horibe¹, Seto Kishimoto¹, Megumi Funakoshi¹, Natsuko Watanabe¹, Narumi Sugihara¹, Kanako Sato¹, Kotaro Takasugi¹, Shoji Kawauchi², Naoto Sasaki¹, Koji Ikeda³, Noriaki Emoto³, Ken-ichi Hirata⁴, Yoshiyuki Rikitake¹ (1.Dept. Med. Pharm., Kobe Pharm. Univ., 2.Educ. Ctr. Clin. Pharm., Kobe Pharm. Univ., 3.Dept. Clin. Pharm. Sci, Kobe Pharm. Univ., 4.Div Cardiovasc. Med., Kobe Univ. Grad. Sch. Med.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0435] Neural stem cell specific ITPA deficiency causes depolarization of neurons, resulting in epileptic seizure and early death in mice

〇Daisuke Tsuchimoto¹, Yuichiro Koga¹, Yoshinori Hayashi^2,3, Nona Abolhassani¹, Yasuto Yoneshima¹, Kunihiko Sakumi¹, Hiroshi Nakanishi⁴, Shinya Toyokuni⁵, Yusaku Nakabeppu¹ (1.Div. of Neurofunc. Genomics, Med. Inst. of Bioreg., Kyushu Univ., 2.Dept. of Agi. Sci. Phar., Fac. of Dent. Sci., Kyushu Univ., 3.Dept. of Physiol., Niho Univ. Schl. of Dent., 4.Dept. of Phar., Fact. of Pharm. Sci., Yasuda Womens Univ., 5.Dept. of Pathol. Biolog. Resp., Grad. Sch. Med., Nagoya Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0436] AUTS2 is required for proper synapse development and mouse social communication

〇Hori Kei¹, Yamashiro Kunihiko⁷, Nagai Taku², Shan Wei², Egusa Saki⁷, Shimaoka Kazumi⁷, Go Yasuhiro³, Tatsumoto Shoji³, Kanno Kouta⁴, Sakamoto Asami⁷, Abe Manabu⁵, Sakimura Kenji⁵, Sohya Kazuhiro⁶, Kunugi Hiroshi⁶, Yamada Kiyofumi², Hoshino Mikio⁷ (1.Dept. of Neurochem., NCNP, Tokyo, 2.Dept. of Neuropsychopharm. Grad. Sch. of Med., Nagoya Univ, 3.Dept. of Brain Sci., Center for Novel Sci. Initiative, NIPS, Okazaki, 4.Dept. of Hum., Facult of Low, Econ & Hum., Kagoshima Univ, 5.Dept. of Cell. Neurobiol., BRI, Univ. of Niigata, 6.Dept. of Mental Dis Res., NCNP, Tokyo, 7.Dept. of Biochem. & Cell Biol., NCNP)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0437(1AW-05-9)] Modelling neurodevelopmental disorders caused by impaired ribosome biogenesis using Drosophila

〇Akari Takai¹, Tomohiro Chiyonobu¹, Ibuki Ueoka², Mizuki Yamaguchi², Ryo Tanaka², Hideki Yoshida², Masamitsu Yamaguchi² (1.Dept. of Pediatrics, Kyoto Prefectural University of Medicine, 2.Dept. of Applied Biology, Kyoto Institute of Technology)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0438] Analysis of novel Drosophila model for neurodevelopmental disorders targeting B-cell lymphoma/leukemia 11

〇Mizuki Yamaguchi¹, Akari Takai², Tomohiro Chiyonobu², Hideki Yoshida^1,3, Masamitsu Yamaguchi^1,3 (1.Dept. of Appl. Biol., Kyoto Inst. of Technol., 2.Dept. of Pediatrics, Kyoto Prefectural Univ. of Medicine, 3.Adv. Insect Res. Promotion Ctr., Kyoto Inst. of Technol.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0439(3AW-20-4)] Molecular pathophysiological protein analysis in carbonyl stress-related schizophrenia

〇Manabu Toyoshima¹, Xuguang Jiang², Tadayuki Ogawa², Tetsuo Ohnishi¹, Shogo Yoshihara², Shabeesh Balan¹, Takeo Yoshikawa¹, Nobutaka Hirokawa² (1.Lab. for Mol. Psy., CBS, RIKEN, 2.Dept. of Cell Biol. & Anat., Grad. Sch. of Med., Univ. of Tokyo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan