[1P-0395] Systematic analysis of disease-related SNPs on Dynamin for the myopathy and neuropathy onset mechanism

Megumi Sato¹, Kenshiro Fujise², Tetsuya Takeda², 〇Motomichi Doi¹ (1.Biomedical RI, AIST, 2.Okayama Univ., Grad. Sch. Med., Dent. Pharm. Sci.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0396] Generation of fish models of pontocerebellar hypoplasia type 1

〇Kazumasa Hada¹, Kei Katou¹, Hakutarou Urushibata¹, Hiroshi Shiraishi¹, Toshikatsu Hanada¹ (1.Dept. of cell Biol., Fuc. of Med., Ooita Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0397] Common conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants

〇Riko Tabuchi¹, Takao Fujisawa¹, Hidenori Ichijo¹ (1.Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo )

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0398] Ischemia-induced DNA methylation and cell survival in cortical neurons.

〇Mayumi Asada¹, Hideki Hayashi¹, Norio Takagi¹ (1.Dept. Applied Biochem., Sch. Pharm., Tokyo Univ. Pharm. and Life Sci.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0399] The mechanism of protection due to opening potassium channel on cellular membrane against neurodegeneration with mitochondrial depolarization.

〇Hiroshi Higashi¹, Toshihiko Kinjo¹, Kyosuke Uno¹, Nobuyuki Kuramoto¹ (1.Department of Molecular Pharmacology, Setsunan University)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0400] Novel degradation pathway of intra-nuclear polyglutamine aggregates in the C. elegans nervous system

〇Xiarepa Aihemaiti^1,2, Yoichi Shinkai¹, Motomichi Doi^1,2 (1.Biomedical RI, AIST, 2.Grad. Sch. of Life & Env. sci., Univ. of Tsukuba.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0401] Essential role of calcium sensor EFCAB1 in formation of cerebral cortex

〇Akihiro Nakamura^1,2, Kenji Miyado², Mitsutoshi Yamada¹, Mamoru Tanaka¹ (1.Sch. of Med., Keio Univ., 2.National Center for Child Health and Development)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0402] The novel mechanism for the ciliary targeting of tetraspanin protein peripherin-2/rds

〇Wataru Otsu^1,2, Ya-Chu Hsu², Jen-Zen Chuang², Ching-Hwa Sung² (1.Dept. of Biomed. Res., Gifu Pharm. Univ., 2.Dept. of Ophthalmol., Weill Cornell Medical College)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0403] Potential roles of the nuclear receptor pathway in the pathogenesis of schizophrenia

〇Yuina Wada^1,2, Tetsuo Ohnishi², Balan Shabeesh², Yoshimi Iwayama², Hisako Ohba², Akiko Watanabe², Yasuko Hisano², Yayoi Nozaki², Tomoko Toyota², Shigeru Matsuoka³, Kazuya Iwamoto⁴, Tomomi Shimogori⁵, Masanari Itokawa⁶, Tetsuyuki Kobayashi¹, Takeo Yoshikawa^1,2, Motoko Maekawa^1,2 (1.Div. of Life Sci., Grad. Sch. of Humanit. and Sci., Ochanomizu Univ., 2.Lab. for Mol. Psych., RIKEN CBS, 3.Oita Univ., 4.Kumamoto Univ., 5.RIKEN CBS, 6.Tokyo Metropolitan Institute of Medical Science)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0404] Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells

〇Yusuke Sakai¹, Hidetoshi Kassai¹, Hisako Nakayama^2,5,6, Masahiro Fukaya³, Tatsuya Maeda^4,7, Kazuki Nakao¹, Kouichi Hashimoto², Hiroyuki Sakagami³, Masanobu Kano⁵, Atsu Aiba¹ (1.Lab. of Anim. Resources., Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Neurophysiol., Grad. Sch. of Biomed and Health Sci., Hiroshima Univ., 3.Dept. of Anat., Sch. of Med., Kitasato Univ., 4.Inst. of Mol. and Cel. Biosci., Univ. of Tokyo, 5.Dept. of Neurophysiol., Grad. Sch. of Med., Univ. of Tokyo, 6.Dept. of physiol., Sch. of Med., Tokyo Women's Med. Univ., 7.Dept. of Biol., Hamamatsu Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan