[2P-280_2SP-03-18] A functional hotspot residue, Asn404, controls the activation in M2 muscarinic receptor (M₂R)

^○Yuya Sugiura¹, Kota Katayama^1,2, Yuji Sumii¹, Ryoji Suno³, Putri Nur Arina Binti Mohd Ariff¹, Norio Shibata¹, Hideki Kandori^1,2 (1.Grad. Sch. Eng., Nagoya Inst. Tech, 2.OptoBioTechnology Research Center., Nagoya Inst, 3.Kansai Medical University. Medical)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-281] Expression and purification of the α-isopropylmalate synthase encoded by LEU9 toward thermodynamic analysis

^○HANA KITAZUME¹, Mayuka Takebayashi², Takayuki Ohnuma², Hiroyuki Ohashi³, Atsushi Kurata², Koichi Uegaki² (1.App. Bio. Chem., Grad. Sch. of Agri, Univ.of Kindai, 2.App. Bio. Chem., Fac. of Agri., Univ. of Kindai, 3.ORIST)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-282] Allosteric inactivation mechanism of the α-isopropylmalate synthase from Saccharomyces cerevisiae

^○KENTO KIZAKI¹, Miki Huruie¹, Hana Kitazume¹, Takayuki Ohnuma², Shigeru Shimamoto³, Atsushi Kurata², Koichi Uegaki² (1.App.Bio.Chem.,Grad.Sch.of Agri.,Univ.of Kindai, 2.App.Bio.Chem.,Fac.of Agri.,Univ.of Kindai, 3.Life Sci.,Fac.of Agri.,Univ.of Kindai)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-283] Structural research on the mechanism of condensate formation of CPEB3, a protein regulates Long-term Memory

^○Harunobu Saito^1,2 (1.Dept. of Mol. Eng., Grad. Sch. of Eng., Univ. of Kyoto, 2.Dept. of App. Life Sci., Grad Sch. of Agr., Univ. of Kyoto)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-284] Structural Dynamics of Parkinson’s Disease-related Protein α-synuclein during Amyloid Fibril Formation by using Rheo-NMR

^○Kei Sato (Dept. of. Mole. Eng., Grad. Sch. of Eng., Univ. of Kyoto)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-285] Structural analysis for Cif homolog in Legionella steigerwaltii (CifLs)

^○Akira NISHIDE², Keito Hiragi¹, Takumi Baba¹, Minsoo Kim², Tsunehiro Mizushima¹ (1.Grad. Sch. of Sci., Univ. of Hyogo, 2.Med. Edu. Ctr., Kyoto Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-286] Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP

^○XIAOHAN CAI¹, Shogo Ito¹, Kentaro Noi², Michio Inoue³, Ryo Ushioda⁴, Yukinari Kato⁵, Kazuhiro Nagata⁴, Kenji Inaba³ (1.Dept. of Mol. Biol., Grad. Sch. of Life Sci., Univ. of Tohoku, 2.Dept. of Bioteh. and Life Sci., Univ. of Tokyo Agr. and Tech., 3.IMRAM, Univ. of Tohoku, 4.Faculty of Life Sci., Univ. of Kyoto Sangyo, 5.Grad. Sch. of Med., Univ. of Tohoku)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-287] GlcNAc/GalNAc-specific fibrinogen-like lectin from a marine invertebrate and its protease activity

^○Keisuke Kinoshita, Tomomitsu Hatakeyama, Hideaki Unno (Grad. Sch. of Eng., Nagasaki Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-288] Discovery and characterization of novel bifunctional drimane-type sesquiterpene synthases in marine bacteria

^○Nhu Ngoc Quynh Vo¹, Yuhta Nomura², Kiyomi Kinugasa¹, Hiroshi Takagi¹, Shunji Takahashi¹ (1.RIKEN CSRS, Nat. Prod. Biosynth. Res. Unit, 2.RIKEN CSRS, Biomol. Charact. Unit)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-289] Development of Amphipathic Thiol Compounds Promoting Oxidative Protein Folding Under High Concentration

^○Mai Kitamura¹, Takahiro Muraoka^1,2 (1.Dept. of Appl. Chem., Grad. Sch. of Eng., Tokyo University of Agriculture and Technology, 2.KISTEC)

The 46th Annual Meeting of the Molecular Biology Society of Japan