[3T17e-03] Suppression of in cellulo crystallization of human neuraminidase1 (NEU1) and application for NEU1 deficiency

^○Jun Tsukimoto¹, Yuto Horii², So-ichiro Nishioka², Toshiki Iniwa², Kohji Itoh^1,2 (1.Department of Medicinal Biotechnology, Institute for Medicinal Research, Graduate School of Pharmaceutical Science, Tokushima University., 2.Department of Medicinal Biotechnology, Institute for Medicinal Research, Graduate School of Pharmaceutical Science, Tokushima University.)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:40 PM - 2:50 PM

[3T17e-04] Development of gene therapy by utilizing AAV vector expressing modified β -Hexosaminidase B for GM2 gangliosidoses

^○Yukiya Ohnishi¹, Daisuke Tsuji^1,2, Nijiho Kamori², Shin-ichi Muramatsu³, Kohji Itoh^1,2 (1.Department of Medicinal Biotechnology, Graduate School of Biomedical Sciences, Tokushima University, 2.Faculty of Pharmaceutical Sciences, Tokushima University, 3.Department of Medicine, Jichi Medical University)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:50 PM - 3:00 PM

[3T17e-05] Gb3Cer expression is induced by leptin in kidney

^○Takahiro Nitta, Hirotaka Kanoh, Kei-ichiro Inamori, Akemi Suzuki, Jin-ichi Inokuchi (Division of Glycopathology, Tohoku Medical and Pharmaceutical University)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 3:00 PM - 3:10 PM

[3T18e-01] Development of a novel CaMKK inhibitor derived from STO-609

^○Satomi Ohtsuka¹, Yui Ozeki², Tsukasa Hujii³, Naoki Kanayama¹, Masaki Mgari¹, Teruhiko Isikawa², Hirosi Tokumitsu¹ (1.Okayama University Graduate School of Interdisciplinary Science and Engineering in Health Systems, 2.Okayama University Graduate School of Education, 3.Okayama University Faculty of Education)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:20 PM - 2:30 PM

[3T18e-02] Regulation of protein phosphatase 1H (PPM1H) activity through the hierarchical phosphorylation

^○Jin Osawa¹, Misato Nakatani¹, Saki Ueta¹, Akari Kashimura¹, Yuiko Inui¹, Kazutoshi Akizuki¹, Yasushi Shigeri², Atsuhiko Ishida³, Isamu Kameshita¹, Noriyuki Sueyoshi¹ (1.Faculty of Agriculture, Kagawa University, 2.Wakayama Medical University, 3.Graduate School of Integrated Arts and Sciences, Hiroshima University)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:30 PM - 2:40 PM

[3T18e-03] Roles of Fyn and FIP200 in the activation of Pyk2

^○Sayomi Nakamine, Shiho Okitsu, Hinako Aida, Wataru Kanashiro, Shinnosuke Arakawa, Hideyuki Yamamoto (Dept. of Biochem., Grad. Sch. of Med., Univ. of Ryukyus, Okinawa, Japan)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:40 PM - 2:50 PM

[3T18e-04] Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262

^○Saito Taro¹, Oba Toshiya¹, Shimizu Sawako¹, Akiko Asada¹, Koichi M. Iijima^2,3, Ando Kanae¹ (1.Dept Biol Sci, Tokyo Met Univ, Tokyo, Japan, 2.Dept Alzheimer's Dis Res, NCGG, Aichi, Japan, 3.Dept Exp Gerontology, Grad Sch Pharm Sci, Nagoya City Univ, Aichi, Japan)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 2:50 PM - 3:00 PM

[3T18e-05] ASK1 suppresses NOD-RIPK2 pathway to regulate inflammatory response in adipocytes

^○Saki Takayanagi, Kengo Watanabe, Hidenori Ichijo (Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 3:00 PM - 3:10 PM

[3T18e-06] Functional roles of the novel RING finger E3 ubiquitin ligase LINCR in innate immune responses

^○Takumi Yokosawa, Yuki Nada, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 92nd Annual Meeting of JBS |Fri. Sep 20, 2019 3:10 PM - 3:20 PM

[1P-001] Control of physical properties of ErbB3 by N-glycans

^○Motoko Takahashi¹, Koji Kato², Naoki Fujitani¹, Atsushi Saito¹, Yoshinao Wada³, Min Yao² (1.Department of Biochemistry, Sapporo Medical University School of Medicine, 2.Laboratory of X-ray structural biology, Faculty of Advanced Life science, Hokkaido University, 3.Department of Molecular Medicine, Research Institute of Osaka Womens and Childrens Hospital)

The 92nd Annual Meeting of JBS