[2P-182] Molecular mechanisms for the expressional control of TRIM48 as a novel ASK1 regulator and its pathophysiological significance in cancer

^○Yusuke Hirata, Kenshin Nakajima, Takuya Noguchi, Atsushi Matsuzawa (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 92nd Annual Meeting of JBS

[2P-183] Identification of a chemical chaperone targeting protein aggregation under ER stress

^○Keisuke Kitakaze^1,2, Shusuke Taniuchi¹, Eri Kawano¹, Yoshimasa Hamada¹, Masato Miyake¹, Miho Oyadomari¹, Hirotatsu Kojima³, Hidetaka Kosako⁴, Tomoko Kuribara⁵, Suguru Yoshida⁵, Takamitsu Hosoya⁵, Seiichi Oyadomari¹ (1.Div. of Mol. Biol., Inst. of Adv. Med. Sci., Tokushima Univ., 2.Dept. of Pharmacol., Kawasaki Med. Sch., 3.DDI, The Univ. of Tokyo, 4.Fujii Memorial Inst. of Med. Sci., Inst. of Adv. Med. Sci., Tokushima Univ., 5.Lab. of Chem. Biosci., Inst. of Biomater. and Bioeng., TMDU)

The 92nd Annual Meeting of JBS

[2P-184] Involvement of ER-resident transmembrane transcription factor OASIS in Nuclear Envelope Stress response

^○Koji Matsuhisa¹, Masayuki Kaneko¹, Sayaka Ogawa², Atsushi Saito², Kazunori Imaizumi¹ (1.Department of Biochemistry, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, 2.Department of Stress Protein Processing, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan)

The 92nd Annual Meeting of JBS

[2P-185] Ribosome binding protein GCN1L1 controls cell cycle and is essential for embryonic development

^○Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atshushi Inose-Maruyama, Ken Itoh (Dept. Stress Res. Sci., Hirosaki Univ. Grad. Sch. of Med.)

The 92nd Annual Meeting of JBS

[2P-186] Mitochondrial Dysfunction in Skin Fibroblasts from Mitochondrial Disease Patients.

^○Asei H. Hirai, Takeshi T. Tokuyama, Shigeru Y. Yanagi (Tokyo University of Pharmacy and Life Sciences. Department of life sciences.)

The 92nd Annual Meeting of JBS

[2P-187] Impact of amino acid metabolism on macrophage inflammation

^○Kento Kurita^1,2, Hiroya Ohta¹, Ibuki Shirakawa¹, Ayaka Ito¹, Miyako Tanaka¹, Hiroshi Arima², Yoshihiro Ogawa^3,4, Takayoshi Suganami¹ (1.Research Institute of Environmental Medicine Nagoya University, 2.Department of Endocrinology and Diabetes Nagoya University, 3.Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 4.AMED-CREST)

The 92nd Annual Meeting of JBS

[2P-188] Molecular chaperone TCP regulates the stability and activity of pyruvate dehydrogenase complex

^○Koh Nakayama (Oxygen Biology, MRI, TMDU)

The 92nd Annual Meeting of JBS

[2P-189] Redox control by reactive sulfur species efflux transport system

^○Masahiro Akiyama¹, Takamitsu Unoki², Eiji Warabi³, Yasuhiro Shinkai¹, Yumi Abiko¹, Isao Ishii⁴, Yamamoto Masayuki⁵, Takaaki Akaike⁶, Yoshito Kumagai¹ (1.Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba, 2.Department of Basic Medical Sciences, National Institute for Minamata Disease, 3.Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 4.Laboratory of Health Chemistry, Showa Pharmaceutical University, 5.Medical Biochemistry, Tohoku University Graduate School of Medicine, 6.Department of Medical Biochemistry, Tohoku University Graduate School of Medicine)

The 92nd Annual Meeting of JBS

[2P-190] Protective effects of polysulfide on zinc-induced neurotoxicity

^○Hirokazu Hara, Ayane Oue, Tetsuro Kamiya, Tetsuo Adachi (Gifu Pharm. Univ.)

The 92nd Annual Meeting of JBS

[2P-191] Different concentrations of berberine result in distinct cellular localization patterns and anticancer effects in a breast cancer cell line

^○Yuki Kurashiki, Haruna Hashida, Daiki Kitaguchi, Satoshi Tanaka, Minoru Sakaguchi (Osaka University of Pharmaceutical Sciences)

The 92nd Annual Meeting of JBS