[2S02m-04] Clinical development of early detection biomarker for pancreatic cancer using aberrant processing of circulating apolipoprotein A2 homodimer reflected by exocrine function of pancreas

^○Kazufumi Honda (Dept. Biomarkers Cancer Early Detection. Natl. Cancer Ctr. Res. Istit.)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 10:30 AM - 11:00 AM

[2S03m-00] Introduction

^○Masaki Okumura (Tohoku University)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 9:00 AM - 9:05 AM

[2S03m-01] Cutting-edge molecular mechanism of amyloidogenesis

^○Young-Ho Lee^1,2 (1.Division of Bioconvergence Analysis, KBSI, 2.Bio-Analytical Science, UST)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 9:05 AM - 9:23 AM

[2S03m-02] Structural and kinetic insights into molecular chaperones in protein folding

^○Tomohide Saio, Koichiro Ishimori (Department of Chemistry, Faculty of Science, Hokkaido University)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 9:23 AM - 9:42 AM

[2S03m-03] Understanding the mechanism by PDI family control proteostasis

^○Masaki Okumura¹, Kenji Inaba² (1.FRIS, Tohoku Univ., 2.IMRAM, Tohoku Univ.)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 9:42 AM - 10:00 AM

[2S03m-04] CFTR misfolding and quality control mechanism as therapeutic targets for cystic fibrosis

^○Tsukasa Okiyoneda (Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 10:00 AM - 10:19 AM

[2S03m-05] Drug Discovery targeted for ER-stress Responsive Enzyme

^○Takao Nomura¹, Takanori Matsumaru¹, Tomoki Haruyama¹, Naoyoshi Maeda¹, Masaki Okumura², Shingo Kanemura², Kenji Inaba², Yasuaki Tamura³, Katsumi Maenaka¹ (1.Faculty of Pharmaceutical Sciences, Hokkaido University, 2.Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 3.Institute for the Promotion of Business-Regional Collaboration, Hokkaido University)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 10:19 AM - 10:38 AM

[2S03m-06] The antipsychotic olanzapine targets proinsulin to endoplasmic reticulum-associated degradation by impairing proper disulfide bond formation

^○Satoshi Ninagawa¹, Tetsuya Okada¹, Hajime Umezawa¹, Tokiro Ishikawa¹, Seiji Torii², Robert Mackin³, Koshi Imami⁴, Yasushi Ishihama⁴, Takahiko Nagamine⁵, Kazutoshi Mori¹ (1.Department of Biophysics, Graduate School of Science, Kyoto University, 2.Gunma University Center for Food Science and Wellness, 3.Department of Biomedical Sciences, Creighton University School of Medicine, 4.Department of Molecular and Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 5.Sunlight Brain Research Center)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 10:38 AM - 10:57 AM

[2S03m-07] Closing Remarks

^○Young-Ho Lee (Division of Bioconvergence Analysis, KBSI)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 10:57 AM - 11:00 AM

[2S04m-00] Introduction

^○Fumika Koyano (Tokyo Metropolitan Institute of Medical Science)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 9:00 AM - 9:02 AM